16 Multiple Sclerosis Clinical Trials in Birmingham, AL (2026)

Q: How do I join a clinical trial in Birmingham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you.

Recruiting Multiple Sclerosis Studies in Birmingham

NCT06433752Recruiting

A Study Evaluating the Real World Experience of Participants Treated With BRIUMVI® (Ublituximab-xiiy) for Relapsing Multiple Sclerosis (RMS)

The purpose of this study is to evaluate safety, effiectiveness, and to gain insight into the treatment experience of participants prescribed BRIUMVI® (ublituximab-xiiy) in the real-world setting...

Birmingham, AL2,000 participantsTG Therapeutics, Inc.

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NCT06401330Recruiting

A Study Using Risk Factors to Determine Treatment for Children With Favorable Histology Wilms Tumors (FHWT)

This phase III trial studies using risk factors in determining treatment for children with favorable tissue (histology) Wilms tumors (FHWT). Wilms Tumor is the most common type of kidney cancer in chi...

Birmingham, ALPHASE31,656 participantsChildren's Oncology Group

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NCT07213804Recruiting

A Three-Part Phase 3 Study of Sofetabart Mipitecan in Participants With Platinum-Resistant (Part A) and Platinum-Sensitive (Parts B and C) Ovarian Cancer

This is a clinical study that has three parts. It is testing a potential new medicine called Sofetabart Mipitecan (Sofe-M) for people with certain types of ovarian, peritoneal, and fallopian tube canc...

Birmingham, ALPHASE31,630 participantsEli Lilly and Company

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NCT07225504Recruiting

A Study to Evaluate the Efficacy and Safety of Remibrutinib in Secondary Progressive Multiple Sclerosis

The purpose of this study is to provide efficacy and safety data for remibrutinib in patients with secondary progressive multiple sclerosis (SPMS)...

Birmingham, ALPHASE31,275 participantsNovartis Pharmaceuticals

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NCT05877963Recruiting

Study to Evaluate Safety, Efficacy and Pharmacokinetics (PK) of a Modified Regimen of Ublituximab

The primary purpose of this phase 3b study is to assess the efficacy of a modified regimen of ublituximab as measured by T1 Gadolinium (Gd)-enhancing lesions and pharmacokinetics in participants with ...

Birmingham, ALPHASE3800 participantsTG Therapeutics, Inc.

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NCT07214532Recruiting

Signatera-Guided CDK4/6 Inhibitor Therapy in Breast Cancer

The purpose of this study is to evaluate the efficacy and safety of ctDNA-guided initiation of CDK4/6 inhibitor therapy using the Signatera™ Designed on Genome test (referred to as "Signatera Genome")...

Birmingham, ALNA725 participantsNatera, Inc.

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NCT07287098Recruiting

A Study of Imlunestrant (LY3484356) in Premenopausal Women With Estrogen Receptor-Positive (ER+) Human Epidermal Growth Factor Receptor 2 Negative (HER2-) Early Breast Cancer

This study will include two groups of patients: Cohort 1 and Cohort 2. Cohort 1: will help researchers learn how a medicine called imlunestrant (LY3484356) affects a specific type of breast cancer. S...

Birmingham, ALPHASE2600 participantsEli Lilly and Company

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NCT07011914Recruiting

Care in Multiple Sclerosis (MS)

This study is structured around three main aims. In Aim 1, investigators will conduct community-based participatory research (CBPR) to develop culturally tailored methods to assess childhood adversit...

Birmingham, AL300 participantsNYU Langone Health

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NCT04322318Recruiting

A Study of Combination Chemotherapy for Patients With Newly Diagnosed DAWT and Relapsed FHWT

This phase II trial studies how well combination chemotherapy works in treating patients with newly diagnosed stage II-IV diffuse anaplastic Wilms tumors (DAWT) or favorable histology Wilms tumors (FH...

Birmingham, ALPHASE2256 participantsChildren's Oncology Group

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NCT07441694Recruiting

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

This study will be conducted to determine the safety, tolerability, dose-limiting toxicity (DLT)s, and maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE)s of INCA036978 administe...

Birmingham, ALPHASE1218 participantsIncyte Corporation

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NCT06782490Recruiting

A Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis Spasticity

The purpose of this study is to evaluate the efficacy, safety, and tolerability of BMS-986368 in participants with Multiple Sclerosis Spasticity...

Birmingham, ALPHASE2200 participantsCelgene

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NCT05004051Recruiting

ViTAA Registry Pre- and Post-Operative Monitoring for Endovascular Aortic Aneurysm Repair and Serial Monitoring for AAA

This is a Prospective Registry study to collect imaging and clinical data both on patients with aortic aneurysm disease undergoing serial monitoring and on patients pre and post-endovascular repair, u...

Birmingham, AL200 participantsViTAA Medical Solutions

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NCT06313593Recruiting

A Study to Evaluate the Safety, Tolerability of INCB160058 in Participants With Myeloproliferative Neoplasms

This study is being conducted to assess the Safety, Tolerability, and Pharmacokinetics of INCB160058 in Participants With Myeloproliferative Neoplasms....

Birmingham, ALPHASE1186 participantsIncyte Corporation

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NCT07309445Recruiting

A Study to Assess Real-World Use and Outcomes of TAR-200 for Participants With Non-Muscle Invasive Bladder Cancer (NMIBC) in the United States

The purpose of this study is to assess how well TAR-200 works in real-word by measuring the time taken from the first TAR-200 insertion to worsening of cancer or until the signs and symptoms of cancer...

Birmingham, AL150 participantsJanssen Research & Development, LLC

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NCT06220201Recruiting

A Study to Evaluate the Safety, Tolerability, Efficacy, and Drug Levels of CC-97540 in Participants With Relapsing Forms of Multiple Sclerosis, Progressive Forms of Multiple Sclerosis or Refractory Myasthenia Gravis (MG) (Breakfree-2)

The purpose of this study is to evaluate the safety, tolerability, efficacy, and drug levels of CC-97540 in participants with Relapsing Forms of Multiple Sclerosis (RMS), Progressive Forms of Multiple...

Birmingham, ALPHASE1120 participantsJuno Therapeutics, Inc., a Bristol-Myers Squibb Company

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NCT03911388Recruiting

HSV G207 in Children With Recurrent or Refractory Cerebellar Brain Tumors

This study is a clinical trial to determine the safety of inoculating G207 (an experimental virus therapy) into a recurrent or refractory cerebellar brain tumor. The safety of combining G207 with a si...

Birmingham, ALPHASE124 participantsM.D. Anderson Cancer Center

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About Multiple Sclerosis Clinical Trials in Birmingham

Multiple sclerosis (MS) is an autoimmune disease where the immune system attacks the protective covering of nerve fibers, causing communication problems between the brain and body. Symptoms vary widely and can include vision problems, fatigue, and mobility issues. Disease-modifying therapies have significantly improved outcomes.

There are currently 16 multiple sclerosis clinical trials recruiting participants in Birmingham, AL. These studies are seeking a combined 10,340 participants. Research is being sponsored by TG Therapeutics, Inc., Children's Oncology Group, Eli Lilly and Company and 9 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Multiple Sclerosis Clinical Trials in Birmingham — FAQ

Are there multiple sclerosis clinical trials in Birmingham?

Yes, there are 16 multiple sclerosis clinical trials currently recruiting in Birmingham, AL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What multiple sclerosis treatments are being tested?

The 16 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for multiple sclerosis.

Data updated July 18, 2026 from ClinicalTrials.gov