7 Myeloproliferative Neoplasms Clinical Trials in Birmingham, AL (2026)

Q: How do I join a clinical trial in Birmingham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you.

Recruiting Myeloproliferative Neoplasms Studies in Birmingham

NCT06479135Recruiting

Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib

This clinical trial is evaluating whether addition of navtemadlin to ruxolitinib treatment will provide more clinical benefit than ruxolitinib alone for patients with Myelofibrosis who have a suboptim...

Birmingham, ALPHASE3600 participantsKartos Therapeutics, Inc.

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NCT07623200Recruiting

A Phase 3 Study of INCA033989 Versus Best Available Therapy in Participants With Essential Thrombocythemia

This study is being conducted to evaluate INCA033989 versus best available therapy in participants with essential thrombocythemia and a CALR mutation previously treated with cytoreductive therapy....

Birmingham, ALPHASE3426 participantsIncyte Corporation

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NCT04176198Recruiting

A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis

This study is a Phase 1/2, multicenter, dose-escalation, open-label trial to assess safety, tolerability, pharmacokinetics and pharmacodynamics of nuvisertib (TP-3654) in patients with intermediate or...

Birmingham, ALPHASE1240 participantsSumitomo Pharma America, Inc.

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NCT06093672Recruiting

Study on Efficacy and Safety of Givinostat Versus Hydroxyurea in Patients With Polycythemia Vera

The goal of this clinical trial is to compare the efficacy and safety of givinostat to hydroxyurea in Jak2V617F-positive high risk polycythemia vera patients....

Birmingham, ALPHASE3220 participantsItalfarmaco

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NCT07441694Recruiting

Study of INCA036978 in Participants With Myeloproliferative Neoplasms

This study will be conducted to determine the safety, tolerability, dose-limiting toxicity (DLT)s, and maximum tolerated dose (MTD) and/or recommended dose for expansion (RDE)s of INCA036978 administe...

Birmingham, ALPHASE1218 participantsIncyte Corporation

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NCT05280509Recruiting

Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib

This study evaluates TL-895, a potent, orally-available and highly selective irreversible tyrosine kinase inhibitor for the treatment of Myelofibrosis. Participants must have MF (PMF, Post PV MF, or P...

Birmingham, ALPHASE170 participantsTelios Pharma, Inc.

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NCT05253131Recruiting

Trial of Selumetinib and Bromodomain Inhibitor With Durvalumab for Sarcomas

A multi-institutional open-label phase 1/2 trial of selumetinib in combination with ZEN-3694 and durvalumab in refractory/unresectable sarcomas including MPNST. The phase 1 portion will be separated i...

Birmingham, ALPHASE241 participantsUniversity of Alabama at Birmingham

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About Myeloproliferative Neoplasms Clinical Trials in Birmingham

Myeloproliferative neoplasms (MPNs) are blood cancers in which the bone marrow overproduces red blood cells, platelets, or white blood cells. Types include polycythemia vera, essential thrombocythemia, and myelofibrosis. Treatment depends on the specific type and risk factors.

There are currently 7 myeloproliferative neoplasms clinical trials recruiting participants in Birmingham, AL. These studies are seeking a combined 1,815 participants. Research is being sponsored by Kartos Therapeutics, Inc., Incyte Corporation, Sumitomo Pharma America, Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Myeloproliferative Neoplasms Clinical Trials in Birmingham — FAQ

Are there myeloproliferative neoplasms clinical trials in Birmingham?

Yes, there are 7 myeloproliferative neoplasms clinical trials currently recruiting in Birmingham, AL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What myeloproliferative neoplasms treatments are being tested?

The 7 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for myeloproliferative neoplasms.

Data updated October 12, 2026 from ClinicalTrials.gov