Recruiting Myelofibrosis Studies in Birmingham
Study of Navtemadlin add-on to Ruxolitinib in JAK Inhibitor-Naïve Patients With Myelofibrosis Who Have a Suboptimal Response to Ruxolitinib
This clinical trial is evaluating whether addition of navtemadlin to ruxolitinib treatment will provide more clinical benefit than ruxolitinib alone for patients with Myelofibrosis who have a suboptim...
A Phase 3 Study of Pacritinib in Patients With Primary Myelofibrosis, Post Polycythemia Vera Myelofibrosis, or Post-Essential Thrombocythemia Myelofibrosis
This study (study ID PAC203 North America; PAC303 ex-North America) is evaluating 200 mg BID of pacritinib compared to physician's choice (P/C) therapy in patients with MF and severe thrombocytopenia ...
KRT-232 Versus Best Available Therapy for the Treatment of Subjects With Myelofibrosis Who Are Relapsed or Refractory to JAK Inhibitor Treatment
This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with myelofibrosis (MF) who no longer benefit from treatment with a JAK inhibitor. Inhibition...
Study of Selinexor in Combination with Ruxolitinib in Myelofibrosis
This is a global, multicenter, 2-part study to evaluate the efficacy and safety of selinexor plus ruxolitinib in JAK inhibitor (JAKi) treatment-naïve myelofibrosis (MF) participants. The study will be...
A Study of Oral Nuvisertib (TP-3654) in Patients With Myelofibrosis
This study is a Phase 1/2, multicenter, dose-escalation, open-label trial to assess safety, tolerability, pharmacokinetics and pharmacodynamics of nuvisertib (TP-3654) in patients with intermediate or...
Study of TL-895 Combined With Ruxolitinib in JAKi Treatment-Naïve MF Subjects and Subjects With MF Who Have a Suboptimal Response to Ruxolitinib
This study evaluates TL-895, a potent, orally-available and highly selective irreversible tyrosine kinase inhibitor for the treatment of Myelofibrosis. Participants must have MF (PMF, Post PV MF, or P...
About Myelofibrosis Clinical Trials in Birmingham
Myelofibrosis is a serious bone marrow disorder that disrupts normal blood cell production, leading to extensive scarring in the bone marrow. It can cause severe anemia, weakness, and an enlarged spleen. Treatment includes JAK inhibitors, blood transfusions, and stem cell transplant.
There are currently 6 myelofibrosis clinical trials recruiting participants in Birmingham, ALABAMA. These studies are seeking a combined 2,044 participants. Research is being sponsored by Kartos Therapeutics, Inc., Swedish Orphan Biovitrum, Karyopharm Therapeutics Inc and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.
Myelofibrosis Clinical Trials in Birmingham — FAQ
Are there myelofibrosis clinical trials in Birmingham?
Yes, there are 6 myelofibrosis clinical trials currently recruiting in Birmingham, ALABAMA. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Birmingham?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.
Are clinical trials in Birmingham free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.
What myelofibrosis treatments are being tested?
The 6 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for myelofibrosis.
Data updated March 2, 2026 from ClinicalTrials.gov