Birmingham, ALABAMA6 Active Studies

Sickle Cell Disease Clinical Trials in Birmingham, ALABAMA

Find 6 actively recruiting sickle cell disease clinical trials in Birmingham, ALABAMA. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
1,092
Enrolling

Recruiting Sickle Cell Disease Studies in Birmingham

RecruitingBirmingham, ALABAMANCT06612268

A Study to Evaluate How Well Etavopivat Works in People With Sickle Cell Disease

This study is conducted to confirm whether etavopivat works well at reducing the number of Vaso-occlusive crisis VOCs (sickle cell pain crises) caused by obstructions in blood vessels in adults and ad...

408 participants
Novo Nordisk A/S
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RecruitingBirmingham, ALABAMANCT06609226

A Research Study Looking at Long-term Treatment With Etavopivat in People With Sickle Cell Disease or Thalassaemia

Etavopivat is a new medicine under development for treating blood disorders like sickle cell disease and thalassaemia. Sickle cell disease and thalassaemia are inherited blood disorders that affect ha...

325 participants
Novo Nordisk A/S
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RecruitingBirmingham, ALABAMANCT06481306

A Study to Evaluate BMS-986470 in Healthy Volunteers and Participants With Sickle Cell Disease

The purpose of this study is to evaluate the safety and tolerability, pharmacokinetics and pharmacodynamics, pH and food effect, and preliminary efficacy of BMS-986470 in healthy volunteers and partic...

184 participants
Bristol-Myers Squibb
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RecruitingBirmingham, ALABAMANCT04657822

Rollover Study for Patients With Sickle Cell Disease Who Have Completed a Prior Novartis-Sponsored Crizanlizumab Study

This is a multi-center multi-national rollover study to allow continued access to crizanlizumab for patients with sickle cell disease (SCD) who are on crizanlizumab treatment in a Novartis-sponsored s...

130 participants
Novartis Pharmaceuticals
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RecruitingBirmingham, ALABAMANCT05861453

Pharmacokinetics, Pharmacodynamics and Safety of Epeleuton in Patients with Sickle Cell Disease

To assess the pharmacokinetics, pharmacodynamics and safety of Epeleuton capsules in adult SCD patients who are aged ≥18 years....

30 participants
Afimmune
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RecruitingBirmingham, ALABAMANCT05456880

BEACON: A Study Evaluating the Safety and Efficacy of BEAM-101 in Patients With Severe Sickle Cell Disease

This is an open-label, single-arm, multicenter, Phase 1/2 study evaluating the safety and efficacy of the administration of autologous base edited CD34+ HSPCs (BEAM-101) in patients with severe SCD...

15 participants
Beam Therapeutics Inc.
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About Sickle Cell Disease Clinical Trials in Birmingham

Sickle cell disease is a group of inherited blood disorders where abnormal hemoglobin causes red blood cells to become rigid and sickle-shaped. It causes pain crises, organ damage, and shortened life expectancy. Treatment includes hydroxyurea, blood transfusions, and gene therapy.

There are currently 6 sickle cell disease clinical trials recruiting participants in Birmingham, ALABAMA. These studies are seeking a combined 1,092 participants. Research is being sponsored by Novo Nordisk A/S, Bristol-Myers Squibb, Novartis Pharmaceuticals and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Sickle Cell Disease Clinical Trials in Birmingham — FAQ

Are there sickle cell disease clinical trials in Birmingham?

Yes, there are 6 sickle cell disease clinical trials currently recruiting in Birmingham, ALABAMA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Birmingham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Birmingham research site will contact you about next steps.

Are clinical trials in Birmingham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Birmingham studies also compensate for your time and travel.

What sickle cell disease treatments are being tested?

The 6 active trials in Birmingham are testing new therapies including novel drugs, biologics, and treatment approaches for sickle cell disease.

Data updated March 2, 2026 from ClinicalTrials.gov