Recruiting Cystic Fibrosis Studies in Boston
Evaluation of VX-121/Tezacaftor/Deutivacaftor in Cystic Fibrosis (CF) Participants 1 Through 11 Years of Age
The purpose of this study is to evaluate the pharmacokinetics, safety, tolerability and efficacy of VX-121/tezacaftor/deutivacaftor (VX-121/TEZ/D-IVA) in CF participants with at least 1 triple combina...
Bionic Pancreas in CFRD
This multi-center randomized controlled trial (RCT) will compare efficacy and safety endpoints using the insulin-only configuration of the iLet Bionic Pancreas System (BP) versus a control group using...
A Study To Evaluate The Safety Of CMTX-101 In People With Cystic Fibrosis
CMTX-101 is a bacterial biofilm disrupting monoclonal antibody being developed as an adjunctive therapy to standard of care antibiotics. The goal of this clinical trial is to assess the safety and tol...
4D-710 in Adult Patients With Cystic Fibrosis
This is a Phase 1/2 multicenter, open-label, single dose trial of 4D-710 investigational gene therapy in adults with cystic fibrosis....
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients with Cystic Fibrosis
The goal of this clinical trial is to learn if drug SPL84 is safe for adult patients with cystic fibrosis (CF). It will also learn if the drug works to treat works to treat CF with a specific mutation...
A Phase 1/2 Trial of SP-101 for the Treatment of Cystic Fibrosis (CF)
This is a Phase 1/2 multicenter, open-label, single dose trial of SP-101 investigational gene therapy in adults with CF who are ineligible for or intolerant to CFTR modulator therapy....
Safety, Tolerability and Efficacy Study of ARCT-032 in People With Cystic Fibrosis
ARCT-032-02 is a Phase 2, open-label, multicenter, multiple-ascending dose study of ARCT-032 in adults with CF who are not eligible for CFTR modulator therapy or are not taking CFTR modulators due to ...
About Cystic Fibrosis Clinical Trials in Boston
Cystic fibrosis is a genetic disorder that causes thick, sticky mucus to build up in the lungs, digestive tract, and other organs. It is caused by mutations in the CFTR gene. CFTR modulator therapies have dramatically improved outcomes, along with airway clearance techniques and nutritional support.
There are currently 7 cystic fibrosis clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 492 participants. Research is being sponsored by Vertex Pharmaceuticals Incorporated, Jaeb Center for Health Research, Clarametyx Biosciences, Inc. and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.
Cystic Fibrosis Clinical Trials in Boston — FAQ
Are there cystic fibrosis clinical trials in Boston?
Yes, there are 7 cystic fibrosis clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Boston?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.
Are clinical trials in Boston free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.
What cystic fibrosis treatments are being tested?
The 7 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for cystic fibrosis.
Data updated March 2, 2026 from ClinicalTrials.gov