NCT06837181 · Jaeb Center for Health Research
Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM)
(SPeCTRuM)
What this study is about
This conducted at multiple hospitals cross-sectional study will include a diverse population of adolescents and adults with CF. The overall Aim is to describe prevalence of diabetes microvascular complications and macrovascular surrogates in people with established CFRD.
View original scientific description
This multicenter cross-sectional study will include a diverse population of adolescents and adults with CF. The overall Aim is to describe prevalence of diabetes microvascular complications and macrovascular surrogates in people with established CFRD.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- Written informed consent (and assent when applicable) obtained from participant or participant's legally authorized representative
- For Adults: Must be able to consent on one own's behalf (i.e., cannot lack cognitive capacity to consent due to the required patient-reported outcomes)
- Be willing and able to adhere to the study protocol requirements
- Age ≥ 12 years at time of enrollment
- CF diagnosis based on two CF causing mutations and/or positive sweat test according to CFF diagnostic criteria
- CFRD diagnosis ≥ 5 years at time of enrollment
Exclusion criteria
- History of any illness or condition that, in the opinion of the investigator might confound the results of the study or pose an additional risk to the subject
- History of transplant
- Pregnancy reported by participant at time of consent or at any point during active study participation Pulse Wave Velocity Exclusion Criteria:
- Erratic, accelerated or mechanically controlled irregular heart rhythms including arrhythmias
- Carotid or aortic valve stenosis
- Peripheral artery disease or leg artery disease
- Generalized constriction or localized spasm of muscular conduit arteries such as seen immediately after hypothermic cardiopulmonary bypass surgery or accompanying Raynaud's phenomena or intense cold.
- Possible exclusions based on investigator medical provider assessment (additional precautions may be followed to allow inclusion):
- Pressure reading should not be conducted on a limb where there is intravenous access, arterio-venous shunt, or where circulation is compromised.
- Pressure reading should not be conducted on the side of the body that a mastectomy was done.
Where
- Birmingham, Alabama
- Los Angeles, California
- Palo Alto, California
- San Diego, California
- Aurora, Colorado
- Miami, Florida
- Atlanta, Georgia
- Iowa City, Iowa
- New Orleans, Louisiana
- Boston, Massachusetts
- Minneapolis, Minnesota
- Albuquerque, New Mexico
And 6 more locations — see the full list below.
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Feb 10, 2026 · Source of record for eligibility and locations