47 Fanconi Anemia Clinical Trials in Boston, MA (2026)

Q: Are there fanconi anemia clinical trials in Boston?

Yes, there are 47 fanconi anemia clinical trials currently recruiting in Boston, MA.

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Q: Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Fanconi Anemia Studies in Boston

NCT06618586Recruiting

Get Social Media and Risk-Reduction Training

This study examines the implementation of the TodaysBaby™ mobile safe sleep intervention program in US hospitals. The main aims of this study are to examine: 1) differences in program penetration and ...

Boston, MA10,000 participantsUniversity of Virginia

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NCT07112924Recruiting

CCM OPEN HF Registry

The registry has been designed to evaluate the long-term safety and efficacy of CCM therapy in a real-world setting....

Boston, MA5,500 participantsImpulse Dynamics

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NCT06588452Recruiting

Manual Versus AI-Assisted Clinical Trial Screening Using Large-Language Models

A prospective randomized controlled trial comparing manual review and AI screening for patient eligibility determination and enrollments. A structured query will identify potentially eligible patients...

Boston, MA4,500 participantsBrigham and Women's Hospital

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NCT03480633Recruiting

Biomechanical Precision Medicine Registry for Patients With and Without Heart Failure

In this single-center, longitudinal observational study, we will comprehensively examine clinical characteristics, proteomic, metabolomic, genomic and imaging data to better understand how different h...

Boston, MA3,000 participantsMassachusetts General Hospital

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NCT04334707Recruiting

Kidney Precision Medicine Project

Acute kidney injury (AKI) and chronic kidney disease (CKD) impose a significant global health burden. Yet, no effective therapies currently exist for AKI, and only a few are available for CKD. Despit...

Boston, MA1,000 participantsIcahn School of Medicine at Mount Sinai

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NCT05873634Recruiting

HeartShare: Combining Omics, Deep Phenotyping, and Electronic Health Records for Heart Failure Subtypes and Treatment Targets

HeartShare is a comprehensive study of heart failure, a common and serious medical condition which occurs when the heart is unable to keep up with the demands of the body, resulting in shortness of br...

Boston, MA1,000 participantsNorthwestern University

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NCT06051058Recruiting

Care Transitions App for Patients With Multiple Chronic Conditions

The objective of this study is to widely implement and evaluate the Care Transitions App in a randomized controlled trial. The app the investigators designed for patients with multiple chronic conditi...

Boston, MA798 participantsBrigham and Women's Hospital

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NCT06876649Recruiting

A Master Protocol to Evaluate the Long-Term Safety of (LY3527727) Pirtobrutinib

The master protocol study J2N-MC-JZNY provides a framework to enable the evaluation of the long-term safety and efficacy of pirtobrutinib after completion of clinical studies evaluating pirtobrutinib....

Boston, MA787 participantsEli Lilly and Company

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NCT04629014Recruiting

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

This study proposes to quantify and describe the quality of life of children with intestinal failure, and to identify the medical and socio-economic factors that impact this quality of life, using dat...

Boston, MA750 participantsBoston Children's Hospital

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NCT06678841Recruiting

ELEVATE-HFpEF Clinical Study

ELEVATE-HFpEF is a prospective, randomized, controlled, double-blinded, multi-center, global, interventional pivotal study evaluating the safety and efficacy of dual chamber personalized pacing compar...

Boston, MA700 participantsMedtronic Cardiac Rhythm and Heart Failure

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NCT05407129Recruiting

Patients and Families Improving Safety in Hospitals by Actively Reporting Experiences

Hospitals ineffectively examine the safety of their processes by relying on voluntary incident reporting (VIR) by clinical staff who are overworked and afraid to report. VIR captures only 1-10% of eve...

Boston, MA656 participantsBoston Children's Hospital

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NCT06015776Recruiting

Purinergic Signaling and the Postmenopausal Heart

There is an increased risk of diastolic heart failure in post menopausal women. Estrogen plays a positive role in regulating molecular pathways in heart remodeling. Such pathways may work through puri...

Boston, MA500 participantsBeth Israel Deaconess Medical Center

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NCT06743659Recruiting

Computerized Decision Support for Identification and Management of Familial Hypercholesterolemia

The goal of this clinical trial is to learn if a computer alert can aid clinicians in identifying patients with a genetic type of high cholesterol, called Familial Hypercholesterolemia. The main quest...

Boston, MA450 participantsBrigham and Women's Hospital

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NCT07422571Recruiting

Body Acceptance After Baby Intervention

The purpose of this study is to learn if a novel online single-session intervention can help improve body dissatisfaction in new moms. The active intervention condition, Body Acceptance After Baby (BA...

Boston, MA375 participantsNortheastern University

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NCT05714085Recruiting

Efficacy, Safety, and Pharmacokinetics of Vericiguat in Pediatric Participants With Heart Failure Due to Left Ventricular Systolic Dysfunction (MK-1242-036)

This study aims to compare the efficacy of vericiguat versus placebo on change in n-terminal pro-brain natriuretic peptide (NTproBNP) from baseline to Week 16 of the Base Period. The primary hypothesi...

Boston, MA342 participantsMerck Sharp & Dohme LLC

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NCT06183437Recruiting

The STOP-MED CTRCD Trial

Cancer therapy-related cardiac dysfunction (CTRCD) is when the heart's ability to pump oxygenated blood to the body is compromised. It is a side effect of cancer therapy which can occur as commonly as...

Boston, MA335 participantsDinesh Thavendiranathan

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NCT04787042Recruiting

Phase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067

This is a multiphase, multicenter study, which includes a Phase 1a open-label, dose escalation monotherapy study of ST-067 given as an SC injection with or without obinutuzumab \[Gazyva®\] pre-treatme...

Boston, MA316 participantsSimcha IL-18, Inc.

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NCT03741777Recruiting

Comparison of Residual Gastric Volume Between Children Who Drink Different Clear Oral Fluid Volume

According to the American Society of Anesthesiologists (ASA) fasting guideline for patients undergoing elective surgery, the 2-hour fasting period is suggested for clear oral fluid (including water, p...

Boston, MA288 participantsBoston Children's Hospital

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NCT04829617Recruiting

Promoting Well-being and Health in Heart Failure

The focus of this study is to test the efficacy of a 12-week, phone-delivered Positive Psychology-Motivational Interviewing (PP-MI) intervention, with additional twice weekly PP and health behavior te...

Boston, MA280 participantsMassachusetts General Hospital

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NCT06939751Recruiting

OPtimal Adult Heart Transplant Immunosuppression With MicroRNA Levels

This study aims to develop and refine a microRNA (miR) biomarker panel that can be used to phenotype net immune state after heart transplantation using circulating miRs (associated with drug doses and...

Boston, MA250 participantsInova Health Care Services

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NCT06536296Recruiting

The Impact of Music Medicine on Preterm Brain Development and Behavior

The investigators are conducting a two-site randomized control trial with the aim of defining the impact of music (M) without or with parent voice (MPV) on very preterm infants' acute and cumulative s...

Boston, MA243 participantsBrigham and Women's Hospital

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NCT06517186Recruiting

Myocardial Mechanisms in Heart Failure With Preserved Ejection Fraction

The purpose of this study is to identify changes in heart tissue structure and biological function in patients with heart failure by performing an endomyocardial biopsy (EMB or heart biopsy) during a ...

Boston, MA180 participantsNorthwestern University

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NCT06950385Recruiting

Phase 3 Trial of eRapa in Patients With Familial Adenomatous Polyposis

The main goal of this clinical trial is to learn if the drug eRapa works to slow down the progression of disease in patients diagnosed with Familial Adenomatous Polyposis (FAP). Researchers will compa...

Boston, MA168 participantsRapamycin Holdings Inc.

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NCT04862221Recruiting

TReatment for ImmUne Mediated PathopHysiology

TReatment for ImmUne Mediated PathopHysiology (TRIUMPH) is a multi-center, three arm, randomized, controlled trial of immunosuppressive therapy for children with acute liver failure. The study will de...

Boston, MA163 participantsNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

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NCT05728697Recruiting

Endoscopic Ultrasound Shear Wave Elastography in Patients With Non-alcoholic Fatty Liver Disease

The goal of this observation study is to assess whether endoscopic ultrasound shear wave elastography (EUS-SWE) may be a useful tool for liver fibrosis screening in patients with elevated body mass in...

Boston, MA150 participantsBrigham and Women's Hospital

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NCT07215715Recruiting

US Benchmarking Clinical Study

The goal of this observational study is to measure shear wave velocity (SWV) in patients with non-reduced left ventricular ejection fraction (LVEF) heart failure and left ventricular hypertrophy, with...

Boston, MA150 participantseMyosound SAS

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NCT05879835Recruiting

KiteLock 4% EDTA Lock Solution for the Prevention of Occlusions in Children With Intestinal Failure

A multi-site, randomized, 2-arm open-label trial to determine if 4% Tetrasodium (EDTA) catheter lock solution is more effective than heparin lock (standard of care) in preventing central venous cathet...

Boston, MA124 participantsSterileCare Inc.

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NCT05627440Recruiting

A SkeleTal Muscle Recovery Intervention With Dietary Protein in Heart Failure

Severe skeletal wasting and catabolic weight loss are highly common among patients with heart failure with reduced ejection fraction (HFrEF). This prospective randomized controlled trial will compare ...

Boston, MA120 participantsTufts Medical Center

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NCT07192952Recruiting

A Study to Learn More About How Safe Finerenone is, When it is Taken for a Longer Time With Standard Treatment, in Children and Young Adults With Heart Failure and Left Ventricular Systolic Dysfunction

Researchers are looking for a better way to treat children and young adults who have heart failure with left ventricular systolic dysfunction (LVSD). Heart failure with left ventricular systolic dysfu...

Boston, MA117 participantsBayer

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NCT07188805Recruiting

A Study to Learn More About How Well Finerenone Works, How Safe it is, and How it Moves Into, Through, and Out of the Body Compared to Placebo When Taken With Standard Treatment in Children With Heart Failure and Left Ventricular Systolic Dysfunction

Researchers are looking for a better way to treat children who have heart failure with left ventricular systolic dysfunction (LVSD). Heart failure is a serious condition where the heart is unable to p...

Boston, MA111 participantsBayer

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NCT05034432Recruiting

The PIVATAL Study -Study of Ventricular Arrhythmia (VTA) Ablation in Left Ventricular Assist Device (LVAD) Patients

To investigate the effect of VTA ablation at the time of LVAD implant to see if it can reduce the incidence of VTA after surgery...

Boston, MA100 participantsUniversity of Rochester

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NCT03549559Recruiting

Imaging Histone Deacetylase in the Heart

The overall goal of this PET-MR imaging trial is to evaluate 11C-Martinostat, a histone deacetylase targeted radioligand, in patients with aortic stenosis, individuals with diabetes, and healthy volun...

Boston, MA96 participantsMassachusetts General Hospital

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NCT06753916Recruiting

ExCrossV Multi Site Trial for Vascularized High Risk Keratoplasty

The main objective of this study is to determine the safety of Ex Vivo Cross Linking (CXL) of donor corneal tissue in participants who have undergone high-risk penetrating keratoplasty....

Boston, MA96 participantsMassachusetts Eye and Ear Infirmary

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NCT07201922Recruiting

A Study to Test Whether Nerandomilast Can Help Slow Down Changes in the Lung in People With a Family History of Pulmonary Fibrosis

This study is open to people aged 40 years or older who have at least 1 family member with pulmonary fibrosis. Pulmonary fibrosis is a condition where lung tissue becomes scarred, making it harder to ...

Boston, MA80 participantsBoehringer Ingelheim

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NCT06253104Recruiting

Changes in Skeletal Muscle Thickness in Patients With Acute Heart Failure

This study aims to determine, via skeletal muscle ultrasound (US), the extent, timing and relationship between skeletal muscle mass loss and outcomes after orthotropic heart transplantation (OHT) and ...

Boston, MA60 participantsTufts Medical Center

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NCT05674643Recruiting

Gastric Assessment of Pediatric Patients Undergoing Surgery

The goal of this pilot prospective cohort study is to examine the reproducibility of gastric volume and emptying as measured by gastric ultrasound and its correlation to a gold-standard test for gastr...

Boston, MA60 participantsBoston Children's Hospital

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NCT05236153Recruiting

Electroanatomic Interactions Between Transcatheter Pulmonary Valve Prostheses and Anatomic Isthmuses in Repaired Tetralogy of Fallot

Individuals with repaired Tetralogy of Fallot (rTOF) remain at risk for sudden cardiac death from ventricular tachycardia (VT). Transcatheter pulmonary valve replacement (TPVR) indications continue to...

Boston, MA60 participantsBoston Children's Hospital

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NCT01788410Recruiting

MRI-Guided Cryoablation to Alleviate Pain in Head, Neck and Spine

The objective of this study is to provide pain relief to patients with facet joint disease or head and neck pain related to compression of a nerve root. The goal is to provide palliative care with sup...

Boston, MA50 participantsBrigham and Women's Hospital

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NCT07202000Recruiting

EXercise and Activin Inhibition to Modulate InflammatioN Effects on Heart Failure and Cognition (EXAMINE-HFC)

The goal of this clinical trial is to learn if therapy with activin ligand-trap biological therapy (an investigational drug) combined with exercise training can improve exercise capacity and cognitive...

Boston, MA48 participantsMassachusetts General Hospital

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NCT07184476Recruiting

Assessment of Microvascular Circulation in the Pediatric Cardiac Surgery Patient

The pediatric cardiac surgery patient endures a tremendous number of physiologic alterations during surgery and cardiopulmonary bypass (CPB) that lasts well into the recovery period. Most of the hemod...

Boston, MA40 participantsBoston Children's Hospital

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NCT05919680Recruiting

A Study of NST-6179 in Subjects With Intestinal Failure-Associated Liver Disease (IFALD).

This is a phase 2a, multicenter, randomized, double-blind, placebo-controlled study to evaluate the safety, tolerability, pharmacokinetics (PK), and pharmacodynamics (PD) of NST-6179 in subjects with ...

Boston, MA36 participantsNorthSea Therapeutics B.V.

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NCT04899102Recruiting

Intermittent Fasting for NAFLD in Adults

NAFLD is a growing threat to public health. Currently, there is a significant need for highly effective treatments for NAFLD. Non-obese NAFLD (BMI\<30kg/m2) is an increasingly recognized condition, so...

Boston, MA25 participantsMassachusetts General Hospital

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NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

Boston, MA20 participantsAdaptimmune

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NCT06972069Recruiting

Tolerance Through Mixed Chimerism (Sip-Tego)

This is an open-label, single-institution study to assess the safety and the efficacy of the Sip-Tego regimen for the induction of donor-specific immunologic unresponsiveness to a renal allograft. The...

Boston, MA12 participantsTatsuo Kawai, MD, PhD

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NCT05452720Recruiting

MASA Valve Early Feasibility Study

The MASA Valve Early Feasibility Study (MVEFS) multi-site interventional clinical trial within the United States of America with each center following a common protocol.The objective of the trial is t...

Boston, MA10 participantsPECA Labs

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NCT06147336Recruiting

A Multi-center, National, Open-label, Prospective Study to Evaluate the Performance of the V-Lap™ System

The objective of this study is to evaluate the safety and performance of the V-LAP System in subjects with New York Heart Association (NYHA) functional class II and III HF, irrespective of left ventri...

Boston, MA10 participantsVectorious Medical Technologies Ltd.

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NCT07476183Recruiting

Assessing the Safety, Tolerability, and Efficacy of APR-2020 in Pediatric and Adolescent Subjects With RPS19 Deficient Diamond-Blackfan Anemia

Brief summary The goal of this clinical trial is to learn if APR-2020 is safe and can help treat Diamond-Blackfan Anemia (DBA) in adolescents and children. The main questions it aims to answer are: ...

Boston, MA4 participantsApriligen, Inc.

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About Fanconi Anemia Clinical Trials in Boston

Fanconi anemia is a rare genetic disorder that affects bone marrow, reducing production of all types of blood cells and increasing cancer susceptibility. It is associated with physical abnormalities and organ defects. Treatment includes blood transfusions, growth factors, and stem cell transplant.

There are currently 47 fanconi anemia clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 34,160 participants. Research is being sponsored by University of Virginia, Impulse Dynamics, Brigham and Women's Hospital and 27 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Fanconi Anemia Clinical Trials in Boston — FAQ

Are there fanconi anemia clinical trials in Boston?

Yes, there are 47 fanconi anemia clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What fanconi anemia treatments are being tested?

The 47 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for fanconi anemia.

Data updated July 13, 2026 from ClinicalTrials.gov