Boston, MA6 Active Studies

Ulcerative Colitis Clinical Trials in Boston, MA

Find 6 actively recruiting ulcerative colitis clinical trials in Boston, MA. Connect with local research sites and explore new treatment options.

6
Active Trials
5
Sponsors
632
Enrolling

Recruiting Ulcerative Colitis Studies in Boston

RecruitingBoston, MANCT05442567

A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)

The study is an extension of two parent studies (MLN0002-3024 \[NCT04779307\] and MLN0002-3025 \[NCT04779320\]). Participants must have participated in one of the previous studies. The purpose of this...

240 participants
Takeda
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RecruitingBoston, MANCT04844606

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks ...

150 participants
Eli Lilly and Company
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RecruitingBoston, MANCT04624230

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

This study, A3921210 is designed to evaluate the efficacy, safety and pharmacokinetics (PK) of tofacitinib in pediatric participants with moderately to severely active UC. In the US and EU, patients w...

120 participants
Pfizer
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RecruitingBoston, MANCT05784246

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Moderately to Severely or Active Ulcerative Colitis

The main purpose of this study is to investigate efficacy, pharmacokinetics and safety of the drug in pediatric participants with moderately to severely active ulcerative colitis (UC)....

60 participants
Eli Lilly and Company
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RecruitingBoston, MANCT04305145

Infliximab for Treatment of Immune Checkpoint Inhibitor Colitis

The goal of this clinical trial is to compare the safety and effectiveness of infliximab compared to steroids for the treatment of immune checkpoint inhibitor-induced colitis (ICI colitis) in patients...

42 participants
Massachusetts General Hospital
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RecruitingBoston, MANCT05642455

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

20 participants
Adaptimmune
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About Ulcerative Colitis Clinical Trials in Boston

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 6 ulcerative colitis clinical trials recruiting participants in Boston, MA. These studies are seeking a combined 632 participants. Research is being sponsored by Takeda, Eli Lilly and Company, Pfizer and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in Boston — FAQ

Are there ulcerative colitis clinical trials in Boston?

Yes, there are 6 ulcerative colitis clinical trials currently recruiting in Boston, MA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 6 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated March 2, 2026 from ClinicalTrials.gov