Boston, MASSACHUSETTS6 Active Studies

Liver Cancer Clinical Trials in Boston, MASSACHUSETTS

Find 6 actively recruiting liver cancer clinical trials in Boston, MASSACHUSETTS. Connect with local research sites and explore new treatment options.

6
Active Trials
6
Sponsors
5,929
Enrolling

Recruiting Liver Cancer Studies in Boston

RecruitingBoston, MASSACHUSETTSNCT06084234

National Liver Cancer Screening Trial

The National Liver Cancer Screening Trial is an adaptive randomized phase IV Trial comparing ultrasound-based versus biomarker-based screening in 5500 patients with cirrhosis from any etiology or pati...

5,500 participants
University of Texas Southwestern Medical Center
View Study Details
RecruitingBoston, MASSACHUSETTSNCT03186898

Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

This phase III trial studies how well radiation therapy with protons works compared with photons in treating patients with liver cancer. Radiation therapy, such as photon therapy, uses high energy x-r...

186 participants
NRG Oncology
View Study Details
RecruitingBoston, MASSACHUSETTSNCT06777316

A Study of an FGFR2/3 Inhibitor (CGT4859) in Patients With Cholangiocarcinoma and Other Advanced Solid Tumors

This is an open-label, phase 1/2 study evaluating the safety, tolerability, pharmacokinetic (what the body does to the drug), pharmacodynamic (what the drug does to the body), and antitumor activity o...

110 participants
Cogent Biosciences, Inc.
View Study Details
RecruitingBoston, MASSACHUSETTSNCT06040099

A US Study to Evaluate Transarterial Radioembolization (TARE) in Combination With Durvalumab and Bevacizumab Therapy in People With Unresectable Hepatocellular Carcinoma Amenable to TARE

The purpose of this study is to measure the efficacy and safety of durvalumab intravenous (IV) solution plus bevacizumab IV solution after transarterial radioembolization (Yttrium 90 glass microsphere...

100 participants
AstraZeneca
View Study Details
RecruitingBoston, MASSACHUSETTSNCT04134559

Checkpoint Inhibition In Pediatric Hepatocellular Carcinoma

This research study is studying an immunotherapy drug (pembrolizumab or KEYTRUDA) as a possible treatment for pediatric hepatocellular carcinoma or hepatocellular neoplasm not otherwise specified (HCN...

18 participants
Allison O'Neill, MD
View Study Details
RecruitingBoston, MASSACHUSETTSNCT04634357

ET140203 T Cells in Pediatric Subjects With Hepatoblastoma, HCN-NOS, or Hepatocellular Carcinoma

Open-label, dose escalation, multi-center, Phase I/II clinical trial to assess the safety/tolerability and determine the recommended Phase II Dose (RP2D) of ET140203 T-cells in pediatric subjects who ...

15 participants
Eureka Therapeutics Inc.
View Study Details

About Liver Cancer Clinical Trials in Boston

Liver cancer most commonly presents as hepatocellular carcinoma (HCC) and is often associated with chronic liver disease or hepatitis. It is one of the fastest-growing causes of cancer death. Treatment options include surgery, liver transplant, ablation, and systemic therapies.

There are currently 6 liver cancer clinical trials recruiting participants in Boston, MASSACHUSETTS. These studies are seeking a combined 5,929 participants. Research is being sponsored by University of Texas Southwestern Medical Center, NRG Oncology, Cogent Biosciences, Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Liver Cancer Clinical Trials in Boston — FAQ

Are there liver cancer clinical trials in Boston?

Yes, there are 6 liver cancer clinical trials currently recruiting in Boston, MASSACHUSETTS. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What liver cancer treatments are being tested?

The 6 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for liver cancer.

Data updated March 2, 2026 from ClinicalTrials.gov