20 Epilepsy Clinical Trials in Boston, NY (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Epilepsy Studies in Boston

NCT06265103Recruiting

Epilepsy Learning Healthcare System (ELHS)

The Epilepsy Learning Health System (ELHS) is a quality improvement and research network to improve outcomes for people with epilepsy. The ELHS is designed as a model of value-based chronic care for e...

Boston, NY100,000 participantsEpilepsy Foundation of America

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NCT01858285Recruiting

Genetics of Epilepsy and Related Disorders

Investigators at Boston Children's Hospital are conducting research in order to better understand the genetic factors which may contribute to epilepsy and related disorders. These findings may help ex...

Boston, NY5,000 participantsBoston Children's Hospital

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NCT06275685Recruiting

Forecasting Seizures Using Intelligent Wearable Technology for Health Tracking

The goal of this interventional study is to develop a personalized seizure risk forecast tool in people with epilepsy. The main questions it aims to answer are: * can we develop a future seizure pro...

Boston, NY3,000 participantsEmpatica, Inc.

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NCT06967727Recruiting

Registry and Natural History of Epilepsy-Dyskinesia Syndromes

The Registry and Natural History of Epilepsy-Dyskinesia Syndromes is focused on gathering longitudinal clinical data as well as biological samples (blood, urine, and/or skin/tissue) from male and fema...

Boston, NY700 participantsBoston Children's Hospital

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NCT06701084Recruiting

Molecular Genetic Mechanisms of Infantile Epilepsies and the Impact of Genetic Diagnosis

The goal of this study is to discover new genetic causes of infantile epilepsies and evaluate the impact of these discoveries on infants with epilepsy and their families....

Boston, NY600 participantsBoston Children's Hospital

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NCT06585605Recruiting

A Retrospective Survey-based Multicenter Study to Delineate the Molecular and Phenotypic Spectrum of Epilepsy-dyskinesia Syndromes

The Epilepsy-Dyskinesia Study aims to advance the understanding of the clinical and molecular spectrum of epilepsy-dyskinesia syndromes, monogenic diseases that cause both movement disorders and epile...

Boston, NY500 participantsBoston Children's Hospital

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NCT04419272Recruiting

Methylphenidate for the Treatment of Epilepsy-related Cognitive Deficits

Methylphenidate (MPH) is a stimulant, FDA-approved for the treatment of attention deficit hyperactivity disorder (ADHD). It is unknown, however, if stimulants would be of benefit for memory and thinki...

Boston, NY226 participantsVA Office of Research and Development

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NCT07110337Recruiting

Diagnosing Epilepsy To EffeCT Change

The purpose of this research is to address the challenges of diagnosing and long-term management of epilepsy in participants whose seizures are not well captured by standard electroencephalography (EE...

Boston, NY210 participantsEpiminder America, Inc.

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NCT07110454Recruiting

Diagnosing Epilepsy To EffeCT Change Long-Term Follow-Up

The purpose of this research is to address the challenges of correctly monitoring, managing, and diagnosing epilepsy in participants whose seizures are not well captured by standard electroencephalogr...

Boston, NY210 participantsEpiminder America, Inc.

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NCT06934356Recruiting

Subcortical Arousal in Perceptual Awareness

The study consists of prospective enrollment of healthy participants and patients with epilepsy, as well as analysis of an existing data set. Healthy participants will be studied with fMRI, eye metric...

Boston, NY202 participantsYale University

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NCT06593951Recruiting

Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1)

The Registry and Natural History Study for Progressive Myoclonus Epilepsy Type 1 (EPM1) is focused on gathering longitudinal clinical data as well as biological samples (blood and/or urine) from male ...

Boston, NY200 participantsBoston Children's Hospital

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NCT07130786Recruiting

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

This is a randomized trial for patients with brain metastases in the primary motor cortex who have not had seizures to receive either the prophylactic anti-seizure medication levetiracetam (also known...

Boston, NY150 participantsAyal A. Aizer, MD

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NCT05944692Recruiting

Epilepsy Seizure Detection With Innovative Tripolar EEG (tEEG)

Concurrent electroencephalography (EEG) and new tripolar EEG (tEEG) will be recorded from adult and pediatric patients. In some patients stereo EEG (sEEG) will also be recorded concurrently....

Boston, NY90 participantsCREmedical

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NCT05406349Recruiting

Neural Mechanisms of Spatial Representations Beyond the Self

Spatial navigation is a fundamental human behavior, and deficits in navigational functions are among the hallmark symptoms of severe neurological disorders such as Alzheimer's disease. Understanding h...

Boston, NY60 participantsBoston University Charles River Campus

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NCT07227857Recruiting

A First-in-human Study of S230815 in Pediatric Participants With KCNT1-related Developmental and Epileptic Encephalopathy

Study CL1-230815-001 (KANDLE) is a Phase Ib/II, First In Human, multicentre, open-label, multiple ascending dose study to assess the safety, tolerability, pharmacokinetics (PK) and pharmacodynamic (PD...

Boston, NY20 participantsInstitut de Recherches Internationales Servier

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NCT07145489Recruiting

Infrared Photobiomodulation in Humans With Epilepsy

Drug-resistant epilepsy represents roughly 40% of people with epilepsy. It is very challenging to stop seizures in this condition, and the treatment options are limited. This study aims to investigate...

Boston, NY13 participantsBeth Israel Deaconess Medical Center

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NCT06063850Recruiting

AMT-260 Gene Therapy Study in Adults With Unilateral Refractory Mesial Temporal Lobe Epilepsy

The main goals of this clinical study are to learn if AMT-260 is safe and tolerable and works to reduce the frequency of seizures in adults with unilateral mesial temporal lobe epilepsy (MTLE)....

Boston, NY12 participantsUniQure Biopharma B.V.

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NCT03868293Recruiting

Low Intensity Focused Ultrasound Epilepsy: A Pilot Trial

The aim of the proposed pilot study is to investigate patient tolerability and efficacy of moderate term, repeated exposure of Pulsed Low-Intensity Focused Ultrasound (PLIFUS) in patients with drug-re...

Boston, NY10 participantsBrigham and Women's Hospital

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NCT06700811Recruiting

Ketogenic Diet for Prevention of Epileptic Spasms in Infantile Onset Genetic Epilepsies

Epileptic spasms (ES) are a predominantly infantile seizure type observed frequently in certain genetic disorders. Ketogenic diet (high ratio of fat to carbohydrate/protein) is an established non-medi...

Boston, NY10 participantsHeather Olson

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NCT06388707Recruiting

A Safety, Tolerability, and Preliminary Efficacy of Low-intensity Focused Ultrasound Neuromodulation in Patients With Drug-resistant Epilepsy

This will be a prospective, open-label, single-arm, multi-center, pilot study to evaluate the safety, tolerability, and preliminary efficacy of low-intensity focused ultrasound (LIFU) neuromodulation ...

Boston, NY8 participantsNaviFUS Corporation

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About Epilepsy Clinical Trials in Boston

Epilepsy is a neurological disorder characterized by recurrent, unprovoked seizures caused by abnormal electrical activity in the brain. It affects about 50 million people worldwide. Treatment includes antiseizure medications, surgery, and neurostimulation devices.

There are currently 20 epilepsy clinical trials recruiting participants in Boston, NY. These studies are seeking a combined 111,221 participants. Research is being sponsored by Epilepsy Foundation of America, Boston Children's Hospital, Empatica, Inc. and 12 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Epilepsy Clinical Trials in Boston — FAQ

Are there epilepsy clinical trials in Boston?

Yes, there are 20 epilepsy clinical trials currently recruiting in Boston, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What epilepsy treatments are being tested?

The 20 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for epilepsy.

Data updated July 13, 2026 from ClinicalTrials.gov