97 Interstitial Cystitis Clinical Trials in Boston, NY (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Interstitial Cystitis Studies in Boston

NCT02269592Recruiting

Study of MGUS, Smoldering Myeloma, Early MDS and CLL to Assess Molecular Events of Progression and Clinical Outcome

Blood cancers occur when the molecules that control normal cell growth are damaged. Many of these changes can be detected by directly examining parts of the cancer or cells in blood. Several alteratio...

Boston, NY10,000 participantsDana-Farber Cancer Institute

View Study Details

NCT04005976Recruiting

Montalcino Aortic Consortium: Precision Medicine for Heritable Thoracic Aortic Disease

The Montalcino Aortic Consortium (MAC) will provide the infrastructure to assemble large cohorts of patients with mutations in known heritable thoracic aortic disease (H-TAD) genes, define the phenoty...

Boston, NY5,000 participantsThe University of Texas Health Science Center, Houston

View Study Details

NCT06122896Recruiting

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

The purpose of this research is to see if adding blood-based tests and symptom review to standard-of-care pancreatic cancer screening procedures can identify cancer early among individuals with increa...

Boston, NY5,000 participantsDana-Farber Cancer Institute

View Study Details

NCT05671133Recruiting

Effectiveness and Implementation of a Clinician Decision Support System to Prevent Suicidal Behaviors

The primary aim of this project are to evaluate a comprehensive, practice-ready, and deployment-focused strategy for improving the prediction and prevention of suicide attempts among a sample of 4,000...

Boston, NY4,000 participantsMassachusetts General Hospital

View Study Details

NCT06702553Recruiting

Nitric Oxide for Reduced Intensive Support in Cardiac Surgery With Cardiopulmonary Bypass

Cardiac surgery is a procedure that is commonly performed worldwide. Despite these technological advances, cardiac surgery remains a high-risk surgery. Among post-operative complications, acute kidney...

Boston, NY3,650 participantsXijing Hospital

View Study Details

NCT01522183Recruiting

Atypical Hemolytic-Uremic Syndrome (aHUS) Registry

Post-marketing safety data on patients treated and untreated with eculizumab or ravulizumab....

Boston, NY3,000 participantsAlexion Pharmaceuticals, Inc.

View Study Details

NCT04028531Recruiting

Understanding Chronic Lymphocytic Leukemia

The purpose of this study is to collect human Chronic Lymphocytic Leukemia tissue samples and medical information, in order to find out more about the causes and biology of chronic lymphocytic leukemi...

Boston, NY2,750 participantsDana-Farber Cancer Institute

View Study Details

NCT05917652Recruiting

The Actuate-CBC Study

The study team will use implementation science to accelerate the uptake of teleconsultationfor burn patients by 1) examining the relationships between clinician perceptions of acceptability, feasibili...

Boston, NY2,183 participantsUniversity of Pennsylvania

View Study Details

NCT07280065Recruiting

REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool

The goal of the REVEAL PTSD study is to test how well the Senseye DT works as a diagnostic test for Post-traumatic Stress Disorder (PTSD) in adults 18 and older who are experiencing one or more sympto...

Boston, NY1,900 participantsSenseye, Inc.

View Study Details

NCT07194265Recruiting

A Clinical Trial Assessing the Safety and Effectiveness of the DurAVR® THV System

Prospective, randomized, controlled, multicenter, international study. Up to 1054 subjects with a severe native calcific aortic stenosis who are determined by the local Heart Team to have an indicati...

Boston, NY1,650 participantsAnteris Technologies Ltd.

View Study Details

NCT06651580Recruiting

Biospecimen Collection to Identify Gene Mutations for High Risk Pancreatic Cancer in Pediatric Patients, INSPPIRE 2 Study

This clinical trial collects blood, saliva, urine, or stool samples to help identify possible genetic mutations that may increase a person's chance at developing pancreatic cancer. Finding genetic mar...

Boston, NY1,600 participantsM.D. Anderson Cancer Center

View Study Details

NCT07610590Recruiting

guideSEQ: Genomic Understanding, Impact, Decision & Ethics in Prenatal Sequencing

This study looks at whether genome sequencing should be used more routinely during pregnancy, even when ultrasounds look normal. Genome sequencing can examine nearly all of a baby's genes and may find...

Boston, NY1,042 participantsColumbia University

View Study Details

NCT00389142Recruiting

Identifying Genetic Causes of IC/BPS

Interstitial cystitis (IC), also called Bladder Pain syndrome (BPS) is a common condition with no known cause or cure. Twin studies and family accounts have suggested that the condition may be genetic...

Boston, NY1,000 participantsBoston Children's Hospital

View Study Details

NCT06970977Recruiting

CRS Questionnaire Validation Project

The 'CRS validation project' consists of a joint effort of 32 medical centers in Europe, the USA, and South Africa to carry out the validation of 2 novel questionnaires designated to measure self-perc...

Boston, NY1,000 participantsThe European Forum for Research and Education in Allergy and Airway Diseases

View Study Details

NCT04629014Recruiting

Prospective Multisite Study of Quality of Life in Pediatric Intestinal Failure

This study proposes to quantify and describe the quality of life of children with intestinal failure, and to identify the medical and socio-economic factors that impact this quality of life, using dat...

Boston, NY750 participantsBoston Children's Hospital

View Study Details

NCT04712812Recruiting

Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia

The Registry and Natural History Study for Early Onset Hereditary Spastic Paraplegia (HSP) is focused on gathering longitudinal clinical data as well as biological samples (skin and/or blood and/or sa...

Boston, NY700 participantsBoston Children's Hospital

View Study Details

NCT05104710Recruiting

Intermuscular Coherence as a Biomarker for ALS

The specific aims of this study are to: 1. Determine if a painless and quick measurement of muscle activity using surface electrodes can help with the diagnosis of ALS. Specifically, we ask if a meas...

Boston, NY650 participantsUniversity of Chicago

View Study Details

NCT03492151Recruiting

Confocal Laser Endomicroscopy as an Imaging Biomarker for the Diagnosis of Pancreatic Cystic Lesions

The study schema is shown in Figure 4. (A) All patients referred to one of the participating academic centers for EUS evaluation of the PCL will be enrolled in the protocol if they satisfy inclusion c...

Boston, NY500 participantsOhio State University Comprehensive Cancer Center

View Study Details

NCT05581004Recruiting

A Study to Evaluate the Safety, Pharmacokinetics, and Activity of Enzelkitug as a Single Agent and in Combination With Checkpoint Inhibitor in Participants With Locally Advanced or Metastatic Solid Tumors

This is a first-in-human study to evaluate the safety, tolerability, pharmacokinetics (PK), and anti-tumor activity of enzelkitug when administered as a single agent and in combination with atezolizum...

Boston, NY450 participantsGenentech, Inc.

View Study Details

NCT06947538Recruiting

Stepped Care for Posttraumatic Stress Disorder Study

Less than 20% of people with PTSD receive any treatment. This study extends a program of research by the investigator focused on developing adaptive (stepped) interventions for PTSD. The adaptive inte...

Boston, NY428 participantsBoston Medical Center

View Study Details

NCT05485376Recruiting

Pulmonary Artery Catheter in Cardiogenic Shock Trial

The primary objective of the PACCS trial is to assess if early invasive hemodynamic assessment and ongoing management with a PAC in patients with cardiogenic shock due to acutely decompensated heart f...

Boston, NY400 participantsTufts Medical Center

View Study Details

NCT05866302Recruiting

Parametric Response Mapping (PRM) for the Detection of Chronic Lung Injury in Hematopoietic Cell Transplant Recipients

The study will have two separate patient cohorts: Cohort 1 will include patients with newly diagnosed chronic graft versus host disease (GVHD), whereas cohort 2 will include patients with newly diagno...

Boston, NY375 participantsUniversity of Michigan Rogel Cancer Center

View Study Details

NCT06910969Recruiting

Multidisciplinary Intervention for Adults With Chronic Graft-versus-host Disease

The goal of this study is to demonstrate the efficacy of a multidisciplinary group-based telehealth intervention (HORIZONS) compared to minimally enhanced usual care for improving self-management and ...

Boston, NY350 participantsMassachusetts General Hospital

View Study Details

NCT06964685Recruiting

Assessment of Support With Impella® Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock

The observational study titled "Observational Assessment of Support with Impella Best Practices in Acute Myocardial Infarction Complicated by Cardiogenic Shock (OASIS-AMICS)" aims to evaluate the safe...

Boston, NY350 participantsAbiomed Inc.

View Study Details

NCT06370182Recruiting

Safety and Effectiveness of Mechanical Thrombectomy Using the Anaconda ANA Funnel Catheter

The objective of this study is to assess the safety and effectiveness of mechanical thrombectomy (MT) using the ANA funnel catheter in its intended use, which is to facilitate the navigation and deplo...

Boston, NY327 participantsAnaconda Biomed S.L.

View Study Details

NCT06740383Recruiting

Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services

The Biomarkers/Biotypes, Course of Early Psychosis and Specialty Services (BICEPS) study aims to understand the early stages of psychotic disorders like Schizophrenia, Schizoaffective Disorder, and Bi...

Boston, NY320 participantsBeth Israel Deaconess Medical Center

View Study Details

NCT07054073Recruiting

HCMR Re-Imaging Study

This study aims to learn what might predict heart problems (like sudden death from a fast heart rhythm or heart failure) in people with a genetic condition called hypertrophic cardiomyopathy (HCM). HC...

Boston, NY314 participantsChristopher Kramer

View Study Details

NCT02860364Recruiting

Comparing Hypothermic Temperatures During Hemiarch Surgery

Hypothermic circulatory arrest is an important surgical technique, allowing complex aortic surgeries to be performed safely. Hypothermic circulatory arrest provides protection to cerebral and visceral...

Boston, NY282 participantsOttawa Heart Institute Research Corporation

View Study Details

NCT07441642Recruiting

A Study to Investigate Efficacy and Safety of FWY003 Compared With Placebo in Participants With Geographic Atrophy Secondary to Age-related Macular Degeneration

To characterize the dose response relationship of FWY003 in participants with geographic atrophy (GA) secondary to age-related macular degeneration (AMD)....

Boston, NY272 participantsNovartis Pharmaceuticals

View Study Details

NCT07214311Recruiting

Evaluation of PLG0206 in Prevention of Recurrent Infection in Patients Undergoing Debridement, Antibiotics, and Implant Retention (DAIR) for Treatment of a Periprosthetic Joint Infection (PJI) Following Knee Arthroplasty

The goal of this clinical trial is to evaluate whether the investigational drug PLG0206 can help reduce recurrence of infection in adults who have undergone total knee replacement and are receiving a ...

Boston, NY240 participantsPeptilogics

View Study Details

NCT04746677Recruiting

Safety and Efficacy of Endovascular Repair of Complex Aortic Pathology With Physician-modified Endovascular Grafts (PMEGs)

The primary objective of this study is to examine the safety and effectiveness of physician-modified endovascular grafts (PMEGs) for endovascular repair of complex aortic pathology in high-risk patien...

Boston, NY220 participantsBeth Israel Deaconess Medical Center

View Study Details

NCT05020002Recruiting

Extracellular RNA Biomarkers of Myotonic Dystrophy

Current methods of measuring the response to new treatments for muscular dystrophies involve the examination of small pieces of muscle tissue called biopsies. The investigators are interested in findi...

Boston, NY215 participantsMassachusetts General Hospital

View Study Details

NCT05361941Recruiting

Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities

This is a pivotal, prospective, multi-center, randomized, concurrent control, patient and assessor-blinded study with two arms: a treatment arm (where subjects will be treated with the EP Granules wit...

Boston, NY204 participantsElute, Inc.

View Study Details

NCT05354622Recruiting

Hereditary Spastic Paraplegia Genomic Sequencing Initiative (HSPseq)

The purpose of the HSP Sequencing Initiative is to better understand the role of genetics in hereditary spastic paraplegia (HSP) and related disorders. The HSPs are a group of more than 80 inherited n...

Boston, NY200 participantsBoston Children's Hospital

View Study Details

NCT01401998Recruiting

ARPKD Database Study

Hepato-renal fibrocystic diseases (HRFD) is a term developed that encompasses rare diseases such as Autosomal Recessive Polycystic Kidney Disease (ARPKD), and other diseases with common features (Joub...

Boston, NY200 participantsChildren's Hospital of Philadelphia

View Study Details

NCT05004051Recruiting

ViTAA Registry Pre- and Post-Operative Monitoring for Endovascular Aortic Aneurysm Repair and Serial Monitoring for AAA

This is a Prospective Registry study to collect imaging and clinical data both on patients with aortic aneurysm disease undergoing serial monitoring and on patients pre and post-endovascular repair, u...

Boston, NY200 participantsViTAA Medical Solutions

View Study Details

NCT05267665Recruiting

Family Involvement in Treatment for PTSD (FIT-PTSD): A Brief, Feasible Method for Enhancing Outcomes, Retention, and Engagement

Although effective treatments for PTSD exist, high rates of treatment dropout and sub-optimal response rates remain common. Incorporating family members in treatment represents one avenue for improvin...

Boston, NY200 participantsVA Office of Research and Development

View Study Details

NCT05998330Recruiting

LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease

The goal of this clinical trial is to evaluate whether early integration of palliative care in the care of hospitalized patients with advanced liver disease (AdvLD) can improve patients' quality of li...

Boston, NY200 participantsMassachusetts General Hospital

View Study Details

NCT06119698Recruiting

Improving Health for Older Adults With Pain Through Engagement

The goal of this project is to conduct a randomized, hybrid type 1 effectiveness-implementation trial (N=200) to evaluate the effectiveness and implementation of a 10-week mind-body and walking progra...

Boston, NY200 participantsMassachusetts General Hospital

View Study Details

NCT07217717Recruiting

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of \[¹⁸F\]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically co...

Boston, NY200 participantsSOFIE

View Study Details

NCT06237335Recruiting

A Phase 2 Study Evaluating Safety and Tolerability of RCT2100 (CFTR mRNA) in Healthy Participants and in Participants With CF

This is the first-in-human study with RCT2100 and is designed to provide safety and tolerability data for future clinical studies....

Boston, NY192 participantsReCode Therapeutics

View Study Details

NCT06549348Recruiting

Radiation Free Study

This is a prospective, randomized, unblinded, multi-center study. Sites were selected from different geographies (EU and US) with different clinical practice to ensure the results are more generalizab...

Boston, NY182 participantsPhilips Clinical & Medical Affairs Global

View Study Details

NCT07023614Recruiting

A Trial to Evaluate the Efficacy and Safety of Ninerafaxstat in Patients With Symptomatic Non-obstructive Hypertrophic Cardiomyopathy

FORTITUDE-HCM is a global, multicenter, double-blind, parallel-group, placebo-controlled Phase 2b study that will assess the efficacy and safety of ninerafaxstat compared to placebo on top of Standard...

Boston, NY165 participantsImbria Pharmaceuticals, Inc.

View Study Details

NCT02998710Recruiting

Natural History Study of Homocystinuria Caused by Cystathionine Beta-Synthase Deficiency (ACAPPELLA)

The purpose of the study is to characterize the clinical course of homocystinuria in pediatric and adult patients aged 1 to 65 years under current clinical management practices...

Boston, NY150 participantsTravere Therapeutics, Inc.

View Study Details

NCT06239116Recruiting

A Study of RM-718 in Healthy Subjects and Patients With MC4R Pathway Impairment

The purpose of this study is to evaluate the safety, tolerability, and PK of RM-718 in healthy subjects with obesity and in patients with MC4R Pathway Impairment...

Boston, NY150 participantsRhythm Pharmaceuticals, Inc.

View Study Details

NCT07078383Recruiting

A Study to Evaluate the Safety and Effectiveness of the Rapidlink Device When Used in Patients Undergoing an Open Surgical Procedure to Repair the Aorta

The Goal of this Clinical Study is to evaluate the safety and effectiveness of the Rapidlink device in the repair or replacement of the supra-aortic vessels during open surgical repair of aortic disea...

Boston, NY150 participantsVascutek Ltd.

View Study Details

NCT04689646Recruiting

Mind Body Syndrome Therapy for Chronic Pain

The goal of this study is to determine if a mind-body intervention can help people suffering from chronic back pain. The study is a randomized, partially blinded trial examining the effectiveness of a...

Boston, NY150 participantsBeth Israel Deaconess Medical Center

View Study Details

NCT06781983Recruiting

Safety and Tolerability of IPH4502 in Patients With Advanced Solid Tumors

This is a first-in-human, open-label, multicenter, Phase 1 study to evaluate the safety, tolerability and preliminary efficacy of IPH4502 and to determine the recommended Phase 2 dose (RP2D) in advanc...

Boston, NY145 participantsInnate Pharma

View Study Details

NCT06240728Recruiting

A Study of NPX887 for Participants With Solid Tumors Known to Express B7-H7/HHLA2

NPX887 is a human, antagonistic immunoglobulin G1 (IgG1) monoclonal antibody targeting B7-H7 (HHLA2) that may potentiate an anti-tumor immune response. The goal of this first-in-human study is to lear...

Boston, NY144 participantsNextPoint Therapeutics, Inc.

View Study Details

NCT06067841Recruiting

A Study to Assess BMS-986460 in Participants With Metastatic Castration-resistant Prostate Cancer

The purpose of this study is to assess the safety, tolerability, and preliminary efficacy of BMS-986460 in men with Metastatic Castration-resistant Prostate Cancer....

Boston, NY140 participantsBristol-Myers Squibb

View Study Details

NCT05934565Recruiting

Mindful Steps 2.0: Promoting Physical Activity in Patients With COPD and HF

The goal of this fully-remote randomized controlled trial is to test the efficacy of Mindful Steps in facilitating physical activity compared to usual standard of care among 136 patients with COPD and...

Boston, NY136 participantsBeth Israel Deaconess Medical Center

View Study Details

NCT06879041Recruiting

A Phase I Study of [225Ac]-AZD2284 in Patients With Metastatic Castration-Resistant Prostate Cancer

The main purpose of the study is to assess the safety and tolerability of AZD2284, AZD2287, and AZD2275....

Boston, NY136 participantsAstraZeneca

View Study Details

NCT06827990Recruiting

GORE® Ascending Stent Graft in the Treatment of De Novo Type A Aortic Dissections

To assess the safety and effectiveness of the ASG device in the treatment of de novo Type A aortic dissections....

Boston, NY112 participantsW.L.Gore & Associates

View Study Details

NCT05304286Recruiting

Psychophysical and Neural Mechanisms Contributing to Chronic Post-Surgical Pain in Adolescents and Adults

The current project will (1) enhance our understanding of the neurobiology of chronic post-surgical pain (CPSP); (2) provide a metric to follow patients with CPSP in the clinic; (3) provide a metric f...

Boston, NY110 participantsMassachusetts General Hospital

View Study Details

NCT05921201Recruiting

Preventing Depression of Chinese American Adolescents by RRE

The goal of this clinical trial is to test if a culturally sensitive mobile health application (Relax, Reflect, Empower-RRE) is feasible and effective in promoting psychological wellbeing and reducing...

Boston, NY110 participantsNortheastern University

View Study Details

NCT06950034Recruiting

A Phase 1 Study of STX-0712 in Patients With Advanced Hematological Malignancies (CMML and AML)

This is a first-in-human, multicenter, open-label, phase 1 study to evaluate the safety, PK, PD and preliminary efficacy of STX-0712 in patients with advanced CMML and AML for whom there are no furthe...

Boston, NY105 participantsSolu Therapeutics, Inc

View Study Details

NCT05490225Recruiting

Access Cannulation Trial II

This is a pivotal, interventional, prospective, single-arm, open-label, multi-site clinical investigation intended to support FDA clearance of the study device based on the safety and efficacy of the ...

Boston, NY100 participantsVoyager Biomedical

View Study Details

NCT06138873Recruiting

Ablation-Index Guided Scar-Mediated Ventricular Tachycardia Ablation in Patients With Ischemic Cardiomyopathy

Over the last decade, radiofrequency catheter ablation (RFCA) has become an established treatment for ventricular arrhythmias (VA). Due to the challenging nature of visualizing lesion formation in rea...

Boston, NY100 participantsRush University Medical Center

View Study Details

NCT07265557Recruiting

Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients

This is a single-center, pilot randomized controlled trial designed to evaluate the feasibility of a definitive trial comparing opioid-free discharge prescriptions to usual care (which includes opioid...

Boston, NY100 participantsMassachusetts General Hospital

View Study Details

NCT05970562Recruiting

Project 4: Ambulatory Biofeedback and Voice Therapy for Patients With Vocal Hyperfunction

Vocal hyperfunction (VH) is the most commonly treated class of voice disorders by speech-language pathologists and voice therapy is the primary curative treatment. Patients and clinicians report that ...

Boston, NY100 participantsMassachusetts General Hospital

View Study Details

NCT07250061Recruiting

Self-Help Cognitive Processing Therapy (CPT)/Women Veterans Network (WoVeN) Study

Posttraumatic stress disorder (PTSD) can have significant impairment on aspects of mental well-being (MWB) including functioning, loneliness, physical health, and quality of life. There are several ev...

Boston, NY100 participantsBoston University

View Study Details

NCT05996627Recruiting

Belumosudil for the Pre-emptive Treatment of Patients With Chronic Graft Versus Host Disease

This phase II trial compares the effect of belumosudil to a placebo in treating patients with chronic graft versus host disease. Chronic graft versus host disease remains a major complication of stem ...

Boston, NY82 participantsFred Hutchinson Cancer Center

View Study Details

NCT06925542Recruiting

A Safety and Efficacy Study Evaluating CTX112 in Adult Subjects With Refractory Autoimmune Disease

This is a single-arm, open-label, multicenter, ascending dose Phase 1 study evaluating the safety and preliminary efficacy of CTX112 in adult subjects with refractory autoimmune diseases, including ac...

Boston, NY80 participantsCRISPR Therapeutics

View Study Details

NCT07071324Recruiting

CF Wellness Program

This study is a pilot randomized control trial (RCT; N=80) comparing the Cystic Fibrosis Wellness Program (CFWP) to usual care (UC) to evaluate (1) Intervention Adherence (completion of the CFWP Coach...

Boston, NY80 participantsJohns Hopkins University

View Study Details

NCT07227207Recruiting

A Study of TSRA-196 in Adults With PiZZ Alpha-1 Antitrypsin Deficiency (AATD)

This is a Phase 1/2, open-label, multi-center, dose escalation (Part 1), dose expansion (Part 2), and single repeat dose (Part 3) study to evaluate the safety, tolerability, efficacy, and PK/PD parame...

Boston, NY72 participantsTessera Therapeutics, Inc.

View Study Details

NCT06994676Recruiting

A Study of CBX-250 in Participants With Relapsed or Refractory Myeloid Leukemias

Study CBX-250-001 is a Phase 1, open-label, dose-escalation study of CBX-250 in participants with relapsed/refractory AML, HR-MDS, CMML, and CML. Participants aged ≥ 12 years are planned to be enrolle...

Boston, NY72 participantsCrossbow Therapeutics, Inc.

View Study Details

NCT07118722Recruiting

Mindfulness-based Cognitive Therapy vs the Health Enhancement Program for Chronic Pain and Depression; The Quiet Focus Study

The goal of this clinical trial is to pilot a randomized controlled trial comparing an adaptation of mindfulness-based cognitive therapy to the health enhancement program for chronic pain and depressi...

Boston, NY60 participantsMassachusetts General Hospital

View Study Details

NCT04833140Recruiting

Estrogen Administration for the Treatment of NASH in Postmenopausal Women

Non-alcoholic fatty liver disease (NAFLD) is a growing epidemic in the United States. Despite this, the treatment options remain limited. Preclinical and preliminary clinical data suggest that estroge...

Boston, NY60 participantsMassachusetts General Hospital

View Study Details

NCT07031323Recruiting

OnTrackCF: Engagement, Feasibility, and Acceptability Study

This is a multi-site, nonrandomized study using mixed methods approach to evaluate the feasibility, acceptability, and user engagement of OnTrackCF for adults with Cystic Fibrosis (AWCF)....

Boston, NY60 participantsBoston Children's Hospital

View Study Details

NCT06674109Recruiting

SAVE-Care (Sodium Glucose Cotransporter-2 Inhibitors [SGLT2i] As Novel Gout Care) Trial

SAVE-Care (Sodium Glucose Cotransporter-2 inhibitors \[SGLT2i\] As Novel Gout Care) Trial is a double-blind randomized placebo-controlled trial (RCT) designed to assess the effect of empagliflozin on ...

Boston, NY60 participantsMassachusetts General Hospital

View Study Details

NCT06703489Recruiting

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

Sphere-9 VT EFS is a prospective, multi-center, non-randomized, unblinded feasibility study. Adult subjects with recurrent, sustained, scar-related monomorphic ventricular tachycardia will be enrolled...

Boston, NY60 participantsMedtronic Cardiac Ablation Solutions

View Study Details

NCT05422794Recruiting

Testing the Addition of Anti-Cancer Drug, ZEN003694 (ZEN-3694) and PD-1 Inhibitor (Pembrolizumab), to Standard Chemotherapy (Nab-Paclitaxel) Treatment in Patients With Advanced Triple-Negative Breast Cancer

This phase Ib trial tests the safety and tolerability of ZEN003694 in combination with an immunotherapy drug called pembrolizumab and the usual chemotherapy approach with nab-paclitaxel for the treatm...

Boston, NY57 participantsNational Cancer Institute (NCI)

View Study Details

NCT07270185Recruiting

Measuring Outcomes With Validated Exercise

Physical activity and its intensity level is a critical determinant of health. Digital Health Technologies, such as wearable accelerometers (wrist-worn watch-like devices), can provide researchers and...

Boston, NY54 participantsBoston University

View Study Details

NCT06088303Recruiting

Enhancing PTSD Treatment Outcomes by Improving Patient-Provider Communication

The purpose of this clinical trial is to learn whether existing treatments for posttraumatic stress disorder (PTSD) can be improved. Two treatments for PTSD, cognitive processing therapy (CPT) and pro...

Boston, NY54 participantsBoston University

View Study Details

NCT05587127Recruiting

Exposure-Based CBT for Avoidant/Restrictive Food Intake in Functional Dyspepsia

Randomized controlled trial of an exposure-based behavioral treatment (CBT) in adults with functional dyspepsia who meet criteria for avoidant/restrictive food intake disorder (ARFID) with weight loss...

Boston, NY50 participantsMassachusetts General Hospital

View Study Details

NCT06991205Recruiting

Web-based Mind-body Program to Improve Resilience Among Risky Substance Users With Persistent Upper Extremity Pain

The investigator aims to conduct a feasibility randomized controlled trial (RCT) (N=50) to test the feasibility, acceptability, and credibility of an asynchronous web-based mind-body intervention (Too...

Boston, NY50 participantsJafar Bakhshaie

View Study Details

NCT06552052Recruiting

A Retrospective and Prospective Natural History of Genetic Vasculopathies

This study will combine retrospective review of medical records from patients with ACTA2 and ongoing collection of clinical data using standardized instruments and intervals on an observational basis ...

Boston, NY50 participantsMassachusetts General Hospital

View Study Details

NCT06949007Recruiting

Yoga for Persistent Post-Surgical Pain (PPSP)

The overall goal of this project is to complete a pilot feasibility randomized controlled trial (RCT) to inform a future fully-powered translational study evaluating yoga for management and resolution...

Boston, NY50 participantsBrigham and Women's Hospital

View Study Details

NCT03750513Recruiting

LET Optimized IMPT in Treating Pediatric Patients With Ependymoma

This phase I trial studies the side effects of linear energy transfer (LET) optimized image modulated proton therapy (IMPT) in treating pediatric patients with ependymoma. Radiation therapy such as LE...

Boston, NY48 participantsM.D. Anderson Cancer Center

View Study Details

NCT06503367Recruiting

Observation Study in Patients Age 0-5 Years With LAMA2-related Congenital Muscular Dystrophy

The goal of this observational study is to understand how young children with LAMA2-related dystrophy move and change over time. We will also learn about how this condition impacts other body systems....

Boston, NY44 participantsNationwide Children's Hospital

View Study Details

NCT04789148Recruiting

Effects of Intranasal Oxytocin in Patients With Arginine-vasopressin Deficiency

This is a randomized, double-blind, placebo-controlled crossover pilot study of single-dose intranasal oxytocin (6 IU and 24 IU) vs. placebo in adult men and women (aged 18 years and above) with argin...

Boston, NY40 participantsElizabeth Austen Lawson

View Study Details

NCT05779423Recruiting

Cryoablation+Ipilimumab+Nivolumab in Melanoma

The aim of this study is to find out whether the combination of two approved drugs, ipilimumab and nivolumab, in combination with cryoablation are safe and effective for participants who have an unres...

Boston, NY37 participantsMassachusetts General Hospital

View Study Details

NCT07137416Recruiting

Testing the Safety of the Combination of Anti-Cancer Drugs CX-5461 (Pidnarulex) and Trastuzumab Deruxtecan (T-DXd) for Human Epidermal Growth Factor Receptor 2 (HER2)-Positive Solid Tumors and Breast Cancer

This phase I trial tests the safety, side effects, and best dose of pidnarulex in combination with trastuzumab deruxtecan in treating patients with breast cancer and other solid tumors that express va...

Boston, NY36 participantsNational Cancer Institute (NCI)

View Study Details

NCT06109909Recruiting

Pilot Study of Neurofeedback for Photosensitivity in Mild Traumatic Brain Injury

The goal of this study is to complete a pilot study testing the feasibility and acceptability of low-intensity pulse-based transcranial stimulation (LIP-tES) neurofeedback intervention for reducing ph...

Boston, NY36 participantsVA Office of Research and Development

View Study Details

NCT04943848Recruiting

rHSC-DIPGVax Plus Checkpoint Blockade for the Treatment of Newly Diagnosed DIPG and DMG

This is a phase I, open label, plus expansion clinical trial evaluating the safety and tolerability of rHSC-DIPGVax in combination with BALSTILIMAB and ZALIFRELIMAB. rHSC-DIPGVax is an off-the-shelf n...

Boston, NY36 participantsAnn & Robert H Lurie Children's Hospital of Chicago

View Study Details

NCT06216704Recruiting

Skeletal Health and Bone Marrow Composition in Adolescents With Cystic Fibrosis

The investigators will be evaluating bone marrow composition via magnetic resonance imaging in adolescents diagnosed with cystic fibrosis (CF) compared to healthy, matched controls. The investigators ...

Boston, NY36 participantsMassachusetts General Hospital

View Study Details

NCT05711615Recruiting

Testing Low-Dose Common Chemotherapy (Liposomal Doxorubicin) in Combination With an Anti-Cancer Drug, Peposertib, in Advanced Sarcoma

This phase I trial tests the safety, side effects, and best dose of combination therapy with liposomal doxorubicin and peposertib in treating patients with sarcoma that has spread from where it first ...

Boston, NY30 participantsNational Cancer Institute (NCI)

View Study Details

NCT07220369Recruiting

Gut Mini-Pill Study

The purpose of this proof-of-concept study in humans is to determine if a noninvasive, ingestible device, called a "mini-pill", can collect gastrointestinal (GI) luminal content samples from 2 differe...

Boston, NY30 participantsTufts University

View Study Details

NCT06810167Recruiting

Assessing Tenapanor as a Treatment of CF-related Constipation.

Tenapanor is the newest FDA-approved drug for IBS with constipation (IBS-C). This study seeks to understand tenapanor as a treatment for cystic fibrosis-related constipation (CFrC) in CF patients. Par...

Boston, NY25 participantsMassachusetts General Hospital

View Study Details

NCT07024615Recruiting

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

Some people with pancreatic ductal cancer (PDAC) have a protein called Claudin 18.2 (CLDN18.2) in their tumor. ASP2138 is thought to work by binding to CLDN18.2 and a protein on a type of immune cell ...

Boston, NY25 participantsAstellas Pharma Global Development, Inc.

View Study Details

NCT06848140Recruiting

Using Non-invasive Brain Stimulation to Treat Word Finding Difficulty in Chronic Traumatic Brain Injury

The purpose of this study is to learn more about how brain stimulation affects word finding problems in people who have a traumatic brain injury (TBI). The type of brain stimulation used is called tra...

Boston, NY24 participantsBeth Israel Deaconess Medical Center

View Study Details

NCT07112378Recruiting

A Study of Dupilumab in Small Children With an Allergic Condition of the Esophagus (Food Pipe): Eosinophilic Esophagitis

This study is researching an experimental drug called dupilumab (called "study drug"). The study is focused on children with active eosinophilic esophagitis (EoE; an inflammatory disease of the esopha...

Boston, NY20 participantsRegeneron Pharmaceuticals

View Study Details

NCT05335434Recruiting

Intraoral Photobiomodulation Therapy to Prevent Oral Mucositis in Patients Undergoing Hematopoietic Cell Transplantation

This is a single center pilot study evaluating intraoral photobiomodulation for the prevention of oral mucositis in patients undergoing myeloablative allogeneic hematopoietic cell transplantation (all...

Boston, NY20 participantsDana-Farber Cancer Institute

View Study Details

NCT03922555Recruiting

ASTX727 in Recurrent/Progressive Non-enhancing IDH Mutant Gliomas

this research study is evaluating the highest dose of ASTX727 that can be administered safely to recurrent/progressive non-enhancing IDH mutant gliomas patients....

Boston, NY18 participantsMassachusetts General Hospital

View Study Details

NCT06611501Recruiting

Glycemic Regulation as Endometriosis Adjunct Treatment

The goal of this pilot trial is to learn if a novel non-hormonal treatment, metformin hydrochloride, works to treat pelvic pain in young women with endometriosis. The main questions it aims to answer ...

Boston, NY14 participantsBoston Children's Hospital

View Study Details

NCT07287397Recruiting

Study is to Assess the Safety and Tolerability of VTx-002 in Participants With ALS

PIONEER-ALS is a Phase 1/2, multicenter, open-label, ascending dose, uncontrolled, first-in-human study that will evaluate the safety, tolerability and effects on clinical and biomarker endpoints of i...

Boston, NY12 participantsVector Y Therapeutics

View Study Details

NCT07357428Recruiting

Connect-One: Early Feasibility Study of Connexus® Brain-Computer Interface (BCI)

The Connect-One Study is an early feasibility study to obtain preliminary device safety information for the Connexus Brain-Computer Interface (BCI). The Connexus BCI is intended to be used as: (1) an ...

Boston, NY2 participantsParadromics

View Study Details

About Interstitial Cystitis Clinical Trials in Boston

Interstitial cystitis/bladder pain syndrome is a chronic condition causing bladder pressure, bladder pain, and sometimes pelvic pain. It primarily affects women and can significantly impact quality of life. Treatment includes dietary changes, bladder instillations, oral medications, and neuromodulation.

There are currently 97 interstitial cystitis clinical trials recruiting participants in Boston, NY. These studies are seeking a combined 56,883 participants. Research is being sponsored by Dana-Farber Cancer Institute, The University of Texas Health Science Center, Houston, Massachusetts General Hospital and 60 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Interstitial Cystitis Clinical Trials in Boston — FAQ

Are there interstitial cystitis clinical trials in Boston?

Yes, there are 97 interstitial cystitis clinical trials currently recruiting in Boston, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What interstitial cystitis treatments are being tested?

The 97 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for interstitial cystitis.

Data updated July 13, 2026 from ClinicalTrials.gov