13 Pancreatic Cancer Clinical Trials in Boston, NY (2026)

Q: How do I join a clinical trial in Boston?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you.

Recruiting Pancreatic Cancer Studies in Boston

NCT06271291Recruiting

Pancreatic Cancer Detection Consortium (PCDC) Prospective Cohorts

This study evaluates individuals without pancreatic cancer, but who have been determined to be at higher-than-average lifetime risk of developing pancreatic cancer to help detect pancreatic cancer or ...

Boston, NY30,000 participantsMayo Clinic

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NCT02000089Recruiting

The Cancer of the Pancreas Screening-5 CAPS5)Study

Johns Hopkins clinical research office quality assurance group will monitor and audit this study at Johns Hopkins. The Sub Investigator at each site will be responsible for internal monitoring at thei...

Boston, NY9,000 participantsJohns Hopkins University

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NCT06122896Recruiting

Prospective Screening for Pancreatic Ductal Adenocarcinoma in High-Risk Individuals

The purpose of this research is to see if adding blood-based tests and symptom review to standard-of-care pancreatic cancer screening procedures can identify cancer early among individuals with increa...

Boston, NY5,000 participantsDana-Farber Cancer Institute

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NCT05006131Recruiting

Pancreatic Cancer Screening for At-risk Individuals

The investigators' goal is to conduct a prospective multicenter study to evaluate the yield and outcomes of screening of pancreas cancer in individuals who are at-risk for pancreatic cancer. We plan t...

Boston, NY1,395 participantsBeth Israel Deaconess Medical Center

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NCT07491445Recruiting

Study of Daraxonrasib and Daraxonrasib + GnP as First-line Treatment in Patients With Metastatic Pancreatic Adenocarcinoma

The purpose of this study is to evaluate the safety and efficacy of an investigational RAS(ON) inhibitor administered as monotherapy or in combination with chemotherapy, compared with standard of care...

Boston, NY900 participantsRevolution Medicines, Inc.

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NCT07217717Recruiting

Using 18F-FAPI PET to Detect Metastatic Disease in Patients That Have Pancreatic Ductal Adenocarcinoma (PDAC)

This is a multi-site, open-label, non-randomized, single dose study to assess the clinical utility of \[¹⁸F\]FAPI-74 PET/CT in the detection of metastatic disease in individuals with pathologically co...

Boston, NY200 participantsSOFIE

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NCT06922591Recruiting

Study to Evaluate the Safety, Tolerability & Efficacy of TNG462 in Combination in PDAC & NSCLC Patients

TNG462-C102 is a Phase 1/2, open-label, multicenter study designed to determine the safety, tolerability, PK, PD, and preliminary antineoplastic activity of oral TNG462 in combination with RMC-6236 or...

Boston, NY183 participantsTango Therapeutics, Inc.

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NCT07377045Recruiting

Clinical Trial of OMTX705 in Combination With Gemcitabine/Nab-Paclitaxel and Tislelizumab in Patients With Advanced/Metastatic Pancreatic Adenocarcinoma

This is a Phase 1b dose escalation trial of OMTX705, an anti-fibroblast activation protein (FAP) antibody-drug conjugate (ADC), in combination with gemcitabine/nab-paclitaxel and tislelizumab in patie...

Boston, NY69 participantsOncomatryx Biopharma S.L.

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NCT06747845Recruiting

Maintenance Niraparib Plus Ipilimumab in Patients With Metastatic Pancreatic Adenocarcinoma Whose Disease Has Not Progressed on Platinum-Based Chemotherapy

The main goal of this study is to look at the effectiveness and anti-tumor activity (preventing growth of the tumor) of the drugs niraparib and ipilimumab, on the patients and their pancreatic cancer....

Boston, NY68 participantsAbramson Cancer Center at Penn Medicine

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NCT07047807Recruiting

PDAC-PATHWAYS: A Digital Informational and Supportive Care App for Patients Initiating Neoadjuvant Therapy for Pancreatic Ductal Adenocarcinoma

This study aims to refine and pilot test PDAC-PATHWAYS, a digital informational and supportive care app for patients who are initiating neoadjuvant therapy for pancreatic ductal adenocarcinoma (PDAC)....

Boston, NY50 participantsMassachusetts General Hospital

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NCT05356117Recruiting

Resistance Exercise Combined With Protein Supplementation in People With Pancreatic Cancer: The RE-BUILD Trial

The purpose of this research is to determine whether a virtually supervised resistance exercise (RE) intervention combined with protein supplementation (PS) is feasible in pancreatic cancer patients i...

Boston, NY45 participantsDana-Farber Cancer Institute

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NCT06850623Recruiting

Acoustic Cluster Therapy (ACT) With Chemotherapy for the Treatment of Locally Advanced Pancreatic Cancer

The purpose of the study is to assess the efficacy and safety of Acoustic Cluster Therapy (ACT) when given in addition to chemotherapy for treatment of Locally Advanced Pancreatic Cancer....

Boston, NY25 participantsEXACT Therapeutics AS

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NCT04150042Recruiting

SHARON: A Clinical Trial for Metastatic Cancer Using Chemotherapy and Patients' Own Stem Cells

The clinical trial is a phase 1, single-arm trial that will evaluate the safety of the investigational treatment on metastatic pancreatic cancer and metastatic breast cancer. The investigational treat...

Boston, NY24 participantsGeneral Oncology, Inc.

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About Pancreatic Cancer Clinical Trials in Boston

Pancreatic cancer begins in the tissues of the pancreas and is often diagnosed at an advanced stage. It is one of the most challenging cancers to treat. Clinical trials are actively investigating new approaches including immunotherapy and combination regimens.

There are currently 13 pancreatic cancer clinical trials recruiting participants in Boston, NY. These studies are seeking a combined 46,959 participants. Research is being sponsored by Mayo Clinic, Johns Hopkins University, Dana-Farber Cancer Institute and 9 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Pancreatic Cancer Clinical Trials in Boston — FAQ

Are there pancreatic cancer clinical trials in Boston?

Yes, there are 13 pancreatic cancer clinical trials currently recruiting in Boston, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Boston?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Boston research site will contact you about next steps.

Are clinical trials in Boston free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Boston studies also compensate for your time and travel.

What pancreatic cancer treatments are being tested?

The 13 active trials in Boston are testing new therapies including novel drugs, biologics, and treatment approaches for pancreatic cancer.

Data updated July 13, 2026 from ClinicalTrials.gov