5 Lupus Clinical Trials in Durham, NC (2026)

Q: How do I join a clinical trial in Durham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you.

Recruiting Lupus Studies in Durham

NCT00512694Recruiting

Duke Lupus Registry

Lupus is a systemic autoimmune disease that can present with many varied symptoms, including joint pain, fevers, kidney disease, and rashes. Lupus can affect anyone, but it is most common in younger w...

Durham, NC1,000 participantsDuke University

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NCT06458075Recruiting

Intervention to Improve Communication and Medication Adherence in Lupus

CO-LEAD is an intervention to improve patient-provider communication and medication adherence among patients with systemic lupus erythematosus (SLE). The purpose of this study is to optimize the cult...

Durham, NCNA480 participantsDuke University

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NCT06581198Recruiting

A Study of Rapcabtagene Autoleucel in Systemic Lupus Erythematosus (SLE) Patients With Active, Refractory Lupus Nephritis (LN)

The purpose of this study is to evaluate the efficacy and safety of rapcabtagene autoleucel (administered once following lymphodepletion) versus Standard of Care (SOC) in patients with systemic lupus ...

Durham, NCPHASE2179 participantsNovartis Pharmaceuticals

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NCT07085104Recruiting

A Study to Investigate the Safety and Preliminary Efficacy of ALLO-329, an Allogeneic CAR T-cell Therapy, in Adults With Autoimmune Disease

This is a first-in-human, single-arm, open-label study evaluating the safety, tolerability, and preliminary efficacy of ALLO-329 in adults with autoimmune diseases: systemic lupus erythematosus (SLE) ...

Durham, NCPHASE166 participantsAllogene Therapeutics

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NCT04457154Recruiting

Pediatric Post-Approval Registry

This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatmen...

Durham, NC60 participantsInspire Medical Systems, Inc.

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About Lupus Clinical Trials in Durham

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, brain, and other organs. It is more common in women and often involves periods of flares and remission. Treatment includes antimalarials, immunosuppressants, and biologics.

There are currently 5 lupus clinical trials recruiting participants in Durham, NC. These studies are seeking a combined 1,785 participants. Research is being sponsored by Duke University, Novartis Pharmaceuticals, Allogene Therapeutics and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lupus Clinical Trials in Durham — FAQ

Are there lupus clinical trials in Durham?

Yes, there are 5 lupus clinical trials currently recruiting in Durham, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What lupus treatments are being tested?

The 5 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for lupus.

Data updated July 19, 2026 from ClinicalTrials.gov