17 Ulcerative Colitis Clinical Trials in Durham, NC (2026)

Q: How do I join a clinical trial in Durham?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you.

Recruiting Ulcerative Colitis Studies in Durham

NCT07609394Recruiting

Duchenne Electronic Health Record Study

This study aims to collect retrospective and prospective, long-term data of patients with dystrophinopathy (including Duchenne, Becker, and female carriers) through electronic transfer. At select clin...

Durham, NC2,500 participantsThe Duchenne Registry

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NCT07216521Recruiting

Intent of Surgery for IPMN

This multicenter retrospective observational cohort study seeks to: 1. Classify surgical intent in patients with resected Intraductal Papillary Mucinous Neoplasms (IPMN) and quantify the proportion o...

Durham, NC2,000 participantsNYU Langone Health

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NCT07198113Recruiting

COMPARE - Pediatric Inflammatory Bowel Disease (PIBD)

The purpose of the study is to compare the clinical effectiveness and safety of newer inflammatory bowel disease (IBD) medications in anti-tumor necrosis factor (TNF) refractory patients with pediatri...

Durham, NC1,100 participantsUniversity of North Carolina, Chapel Hill

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NCT07674758Recruiting

Modeling Mortality in Duchenne Muscular Dystrophy Cardiomyopathy: Identification of Surrogate Outcome Measures for DMD Drug Trials

Dystrophin associated heart dysfunction is a leading cause of death in patients with Duchenne and Becker Muscular dystrophy (DMD/BMD) and Duchenne and Becker muscular dystrophy carriers (MDC); however...

Durham, NC1,000 participantsVanderbilt University Medical Center

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NCT05046600Recruiting

Registry of Arthrex Hand and Wrist Products

A Multi-Center, Prospective Registry to Evaluate the Continued Safety and Effectiveness of Hand and Wrist Products...

Durham, NC650 participantsArthrex, Inc.

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NCT07127978Recruiting

A Study Evaluating the Real-World Experience of Givinostat in Patients With Duchenne Muscular Dystrophy

This is a prospective observational study conducted to evaluate safety, tolerability, and functional outcomes of patients with DMD newly initiating oral givinostat or having started therapy within 6 m...

Durham, NC300 participantsITF Therapeutics LLC

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NCT07298356Recruiting

Automated Applanation Tonometry - Updated

Goldmann Applanation Tonometry (GAT) is considered the clinical gold standard for eye pressure measurements and yet it is known to be a subjective measurement with limited repeatability and limited po...

Durham, NCNA200 participantsDuke University

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NCT03190837Recruiting

A Long-term Follow-up Study of Gaucher Disease

The study aims are to: a) identify the long-term natural history of Gaucher disease, b) evaluate long-term treatment efficacy of enzyme replacement therapy (ERT) and substrate reduction therapy (SRT),...

Durham, NC200 participantsDuke University

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NCT02127398Recruiting

Stool Transplants to Treat Refractory Clostridium Difficile Colitis

It has been shown that restoration of the normal makeup of the bowel bacterial population is the most effective way to treat recurrent colitis due to Clostridium difficile. Restoration of the normal b...

Durham, NCPHASE277 participantsDuke University

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NCT04457154Recruiting

Pediatric Post-Approval Registry

This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatmen...

Durham, NC60 participantsInspire Medical Systems, Inc.

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NCT07223944Recruiting

A Gaucher Disease Gene Therapy Trial With FLT201

This study is a Phase 3, non-randomized, multicenter, efficacy and safety study in adult patients with Gaucher disease Type 1, on stable treatment with enzyme replacement therapy (ERT) or substrate re...

Durham, NCPHASE345 participantsSpur Therapeutics

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NCT07031336Recruiting

Photon-counting CT in Chest Imaging

Purpose and objective: This project aims to evaluate photon-counting computed tomography (PCCT) quantitative accuracy using COPDGene subjects. The goal is to establish acquisition protocols for PCCT s...

Durham, NCNA40 participantsDuke University

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NCT07264790Recruiting

Assessment of Topical Minoxidil on Intraoperative Flap Perfusion and Cutaneous Flap Viability in Breast Recon

The purpose of the study is to determine whether pharmacologic delay using minoxidil in patients undergoing bilateral risk reducing mastectomy with reconstruction could achieve improvement in flap per...

Durham, NCPHASE125 participantsDuke University

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NCT07024615Recruiting

A Study of ASP2138 Given Before Surgery, Then Chemotherapy After Surgery, in People With Pancreatic Ductal Cancer

Some people with pancreatic ductal cancer (PDAC) have a protein called Claudin 18.2 (CLDN18.2) in their tumor. ASP2138 is thought to work by binding to CLDN18.2 and a protein on a type of immune cell ...

Durham, NCPHASE125 participantsAstellas Pharma Global Development, Inc.

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NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

Durham, NCPHASE120 participantsAdaptimmune

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NCT05487599Recruiting

A Clinical Trial of PR001 (LY3884961) in Patients With Peripheral Manifestations of Gaucher Disease (PROCEED)

Study J3Z-MC-OJAE is a Phase 1/2, multicenter, open-label, dose-finding study of LY3884961 evaluating the safety and tolerability in adults with peripheral manifestations of GD. Up to 3 dose levels o...

Durham, NCPHASE115 participantsPrevail Therapeutics

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NCT07037836Recruiting

Inhaled Treprostinil (Tyvaso Nebulizer) For COPD Patients With Hypoxemia

The goal of this clinical trial is to evaluate whether inhaled Treprostinil (Tyvaso) can improve oxygen delivery and blood flow in the lungs in adults (age ≥40) with chronic obstructive pulmonary dise...

Durham, NCPHASE210 participantsBastiaan Driehuys

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About Ulcerative Colitis Clinical Trials in Durham

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 17 ulcerative colitis clinical trials recruiting participants in Durham, NC. These studies are seeking a combined 8,267 participants. Research is being sponsored by The Duchenne Registry, NYU Langone Health, University of North Carolina, Chapel Hill and 10 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in Durham — FAQ

Are there ulcerative colitis clinical trials in Durham?

Yes, there are 17 ulcerative colitis clinical trials currently recruiting in Durham, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Durham?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Durham research site will contact you about next steps.

Are clinical trials in Durham free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Durham studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 17 active trials in Durham are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated July 18, 2026 from ClinicalTrials.gov