Recruiting Head and Neck Cancer Studies in Irvine
Testing What Happens When an Immunotherapy Drug (Pembrolizumab) is Given by Itself Compared to the Usual Treatment of Chemotherapy With Radiation After Surgery for Recurrent Head and Neck Squamous Cell Carcinoma
This phase II trial studies the effect of pembrolizumab alone compared to the usual approach (chemotherapy \[cisplatin and carboplatin\] plus radiation therapy) after surgery in treating patients with...
A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer
This study aims to investigate toripalimab with chemotherapy in participants with nasopharyngeal cancer....
Activity and Safety of Danvatirsen and Pembrolizumab in HNSCC
Open-label, Phase II, randomized, controlled study evaluating the efficacy and safety of danvatirsen in combination with pembrolizumab compared with pembrolizumab alone as first-line treatment of pati...
Testing Nivolumab and Ipilimumab Immunotherapy With or Without the Targeted Drug Cabozantinib in Recurrent, Metastatic, or Incurable Nasopharyngeal Cancer
This phase II trial tests how well nivolumab and ipilimumab immunotherapy with or without cabozantinib works in treating patients with nasopharyngeal cancer that has come back (after a period of impro...
About Head and Neck Cancer Clinical Trials in Irvine
Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.
There are currently 4 head and neck cancer clinical trials recruiting participants in Irvine, CALIFORNIA. These studies are seeking a combined 419 participants. Research is being sponsored by National Cancer Institute (NCI), Coherus Oncology, Inc., Flamingo Therapeutics NV. Clinical trial participation is free and participants receive study-related medical care at no cost.
Head and Neck Cancer Clinical Trials in Irvine — FAQ
Are there head and neck cancer clinical trials in Irvine?
Yes, there are 4 head and neck cancer clinical trials currently recruiting in Irvine, CALIFORNIA. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Irvine?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Irvine research site will contact you about next steps.
Are clinical trials in Irvine free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Irvine studies also compensate for your time and travel.
What head and neck cancer treatments are being tested?
The 4 active trials in Irvine are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.
Data updated March 2, 2026 from ClinicalTrials.gov