7 Colorectal Cancer Clinical Trials in Jacksonville, NC (2026)

Q: How do I join a clinical trial in Jacksonville?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you.

Recruiting Colorectal Cancer Studies in Jacksonville

NCT06445062Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

The purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibitors combined with Standard(s) of Care (SOC...

Jacksonville, NC1,130 participantsRevolution Medicines, Inc.

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NCT05410977Recruiting

Collecting Blood and Stool Samples to Detect Colorectal Cancer or Advanced Neoplasia in Lynch Syndrome Patients

This study collects blood and stool samples from patients with suspected or diagnosed Lynch syndrome to evaluate a deoxyribonucleic acid (DNA) screening technique for the detection of colorectal cance...

Jacksonville, NC950 participantsMayo Clinic

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NCT06252649Recruiting

Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation

The aim of this study is to compare progression free survival (PFS) in treatment-naïve participants with KRAS p.G12C mutated metastatic colorectal cancer (mCRC) receiving sotorasib, panitumumab and FO...

Jacksonville, NC450 participantsAmgen

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NCT06948448Recruiting

A Study to Evaluate the Safety and Efficacy of Two Dose Levels of ONO-4578 With Opdivo®, in Combination With mFOLFOX6 and Bevacizumab Versus Standard of Care in Participants With Non-MSI-H/dMMR, PD-L1 Positive Advanced Colorectal Cancer

The purpose of this study is to evaluate the safety and efficacy of two dose levels of ONO-4578 with Opdivo® when added to mFOLFOX6 and bevacizumab versus SOC as first-line treatment for advanced CRC....

Jacksonville, NC144 participantsOno Pharmaceutical Co., Ltd.

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NCT07023289Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide. The purpose of this study is to assess change in disease activity when telisotuzumab adizutecan is given alone comp...

Jacksonville, NC140 participantsAbbVie

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NCT07618273Recruiting

Smart Symptom Tracking ALEX Application for Tracking and Monitoring Gastrointestinal Health, Smart Horizons Pilot Trial

This clinical trial compares the impact of the Smart Symptom Tracking ALEX application (app) to standard symptom-tracking practices in tracking and monitoring gastrointestinal (GI) symptoms in young a...

Jacksonville, NC50 participantsMayo Clinic

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NCT04991948Recruiting

Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer

The purpose of the CYAD-101-002 study is to assess the safety and clinical activity of CYAD-101 in patients with unresectable metastatic colorectal cancer administered concurrently with FOLFOX chemoth...

Jacksonville, NC34 participantsCelyad Oncology SA

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About Colorectal Cancer Clinical Trials in Jacksonville

Colorectal cancer starts in the colon or rectum and is the third most common cancer diagnosed in both men and women. Early detection through screening significantly improves outcomes. Treatments include surgery, chemotherapy, radiation, and targeted therapies.

There are currently 7 colorectal cancer clinical trials recruiting participants in Jacksonville, NC. These studies are seeking a combined 2,898 participants. Research is being sponsored by Revolution Medicines, Inc., Mayo Clinic, Amgen and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Colorectal Cancer Clinical Trials in Jacksonville — FAQ

Are there colorectal cancer clinical trials in Jacksonville?

Yes, there are 7 colorectal cancer clinical trials currently recruiting in Jacksonville, NC. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Jacksonville?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Jacksonville research site will contact you about next steps.

Are clinical trials in Jacksonville free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Jacksonville studies also compensate for your time and travel.

What colorectal cancer treatments are being tested?

The 7 active trials in Jacksonville are testing new therapies including novel drugs, biologics, and treatment approaches for colorectal cancer.

Data updated July 13, 2026 from ClinicalTrials.gov