Los Angeles, CA9 Active Studies

Crohns Disease Clinical Trials in Los Angeles, CA

Find 9 actively recruiting crohns disease clinical trials in Los Angeles, CA. Connect with local research sites and explore new treatment options.

9
Active Trials
6
Sponsors
3,558
Enrolling

Recruiting Crohns Disease Studies in Los Angeles

RecruitingLos Angeles, CANCT06430801

A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)

The purpose of this protocol is to evaluate the efficacy and safety of tulisokibart in participants with moderately to severely active Crohn's disease. Study 1's primary hypotheses are that at least 1...

1,200 participants
Merck Sharp & Dohme LLC
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RecruitingLos Angeles, CANCT05781152

Clinical, Imaging, and Endoscopic Outcomes of Children Newly Diagnosed With Crohn's Disease

Crohn's disease (CD) is a condition that causes inflammation (swelling, redness) of the lining and wall of the small intestine, large intestine, or both. CD may be associated with abdominal cramps/pai...

900 participants
Connecticut Children's Medical Center
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RecruitingLos Angeles, CANCT06227910

A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease

The main aim of this study is to learn whether vedolizumab and upadacitinib given together (also called dual targeted therapy or DTT) reduces bowel inflammation and ulcers in the bowel compared to ved...

396 participants
Takeda
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RecruitingLos Angeles, CANCT06257706

VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease

Transmural healing (TMH) is recognized as a potentially important measure of Crohn's disease (CD) activity but not a formal target. Observational studies suggest that TMH may be associated with better...

304 participants
Alimentiv Inc.
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RecruitingLos Angeles, CANCT06233461

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease

Crohn's disease (CD) is a long-lasting condition causing inflammation that can affect any part of the gut. The purpose of this study is to evaluate the efficacy and safety of TAK-279 versus placebo in...

268 participants
Takeda
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RecruitingLos Angeles, CANCT05660746

Precise Infliximab Exposure and Pharmacodynamic Control

Approximately 3 million people in the United States are living with inflammatory bowel disease, which includes Crohn's Disease (CD). There are limited treatment options approved for use in children an...

180 participants
Children's Hospital Medical Center, Cincinnati
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RecruitingLos Angeles, CANCT04779320

A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)

Vedolizumab is a medicine that helps to reduce inflammation and pain in the digestive system. In this study, children and teenagers with moderate to severe Crohn's disease will be treated with vedoliz...

120 participants
Takeda
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RecruitingLos Angeles, CANCT06045754

A Study of Vedolizumab Intravenous (IV) and Adalimumab or Vedolizumab and Ustekinumab in Adults With Crohn's Disease

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with adalimumab or vedolizumab (VDZ) together with ustekinumab (UST) in adults with mode...

100 participants
Takeda
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RecruitingLos Angeles, CANCT05509777

A Study of Mirikizumab (LY3074828) in Pediatric Participants With Crohn's Disease

Study participants will be screened during the platform study and randomly assigned to receive mirikizumab or another intervention. The purpose of the mirikizumab study is to evaluate efficacy, safety...

90 participants
Eli Lilly and Company
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About Crohns Disease Clinical Trials in Los Angeles

Crohn's disease is a chronic inflammatory bowel disease that causes inflammation anywhere in the digestive tract, most commonly in the small intestine and colon. Symptoms include abdominal pain, diarrhea, fatigue, and weight loss. Treatment includes anti-inflammatory drugs, immunosuppressants, biologics, and surgery.

There are currently 9 crohns disease clinical trials recruiting participants in Los Angeles, CA. These studies are seeking a combined 3,558 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Connecticut Children's Medical Center, Takeda and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Crohns Disease Clinical Trials in Los Angeles — FAQ

Are there crohns disease clinical trials in Los Angeles?

Yes, there are 9 crohns disease clinical trials currently recruiting in Los Angeles, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What crohns disease treatments are being tested?

The 9 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for crohns disease.

Data updated March 2, 2026 from ClinicalTrials.gov