13 Lupus Clinical Trials in Los Angeles, CA (2026)

Q: How do I join a clinical trial in Los Angeles?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you.

Recruiting Lupus Studies in Los Angeles

NCT05934149Recruiting

Lupus Landmark Study: A Prospective Registry and Biorepository

The purpose of the registry and biorepository is to provide a mechanism to store clinical data, linked biospecimens and molecular data to support the conduct of future research on Systemic Lupus Eryth...

Los Angeles, CA3,500 participantsLupus Research Alliance

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NCT07213908Recruiting

Comparing Two School-Based Sleep Health Interventions To Promote Sleep Quality in Youth

The goal of this clinical trial is to conduct a comparative effectiveness trial that will evaluate two school-based interventions to improve adolescent sleep health: the standard Sleep Health Educatio...

Los Angeles, CANA1,320 participantsChildren's Hospital Los Angeles

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NCT07691970Recruiting

Rollover Study for Participants Who Have Completed a Previous Clinical Study With Anifrolumab (Saphnelo) and Clinically Benefited From Continued Treatment

The purpose of this study is to provide continued access to anifrolumab to eligible participants who are continuing to derive clinical benefit from treatment at the end of a parent clinical study, as ...

Los Angeles, CAPHASE31,072 participantsAstraZeneca

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NCT05452031Recruiting

A Dyadic Sleep Health Approach for Persons With Alzheimer's Disease and Caregivers

This is a randomized controlled trial over 5 years, using Stage II of the NIH-defined stage model for behavioral intervention development. We will evaluate the efficacy of the sleep intervention progr...

Los Angeles, CANA672 participantsUniversity of California, Los Angeles

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NCT07484217Recruiting

Clinical Assessment of Response in the Treatment of Depression With Daytime Sleepiness Using Solriamfetol

CLARITY (Clinical Assessment of Response in the Treatment of Depression with Daytime Sleepiness Using Solriamfetol) is a Phase 3, double-blind, placebo-controlled, multicenter randomized withdrawal tr...

Los Angeles, CAPHASE3508 participantsAxsome Therapeutics, Inc.

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NCT05799378Recruiting

Effects of Stopping Hydroxychloroquine in Elderly Lupus Disease

Hydroxychloroquine (HCQ) is a systemic lupus erythematosus (SLE) medication that has been very effective in reducing lupus disease activity and keeping patients stable with reduced symptoms. Despite a...

Los Angeles, CAPHASE3330 participantsNYU Langone Health

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NCT05576090Recruiting

UCLA REST Study (REsearch on Sleep Techniques)

Sleep disturbance has a range of negative effects on psychosocial and biological processes important for academic and social success as well as mental and physical health among adolescents and young a...

Los Angeles, CANA240 participantsUniversity of California, Los Angeles

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NCT06043440Recruiting

Down Syndrome Obstructive Sleep Apnea

The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) w...

Los Angeles, CAPHASE2230 participantsBrigham and Women's Hospital

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NCT07175285Recruiting

A Study in Participants With Active Systemic Lupus Erythematosus With Inadequate Response to Glucocorticoids and ≥2 Immunosuppressants

The purpose of this study is to characterize the efficacy and safety of current standard of care treatment options in participants with active systemic lupus erythematosus (SLE; including lupus nephri...

Los Angeles, CA223 participantsBristol-Myers Squibb

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NCT07332481Recruiting

A Study of Enpatoran in Participants With Cutaneous Manifestations of Lupus With or Without Systemic Disease

The purpose of this global, multicenter, Phase 3 study is to evaluate the efficacy and safety of enpatoran over 24 weeks in participants with active cutaneous manifestations of lupus erythematosus wit...

Los Angeles, CAPHASE3202 participantsEMD Serono Research & Development Institute, Inc.

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NCT06996652Recruiting

An Exploratory Study of the Potential for Rational Immune System Manipulation to Prevent Emergence of Synucleinopathy Manifestations in Persons With REM Sleep Behavior Disorder (RBD)

This is a phase 2 study to assess the ability of adalimumab as compared to placebo to reduce or prevent progression of synuclein-related neurodegeneration in persons with idiopathic REM Sleep Behavior...

Los Angeles, CAPHASE2108 participantsYale University

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NCT05835310Recruiting

An Efficacy and Safety Study of Intravenous Anifrolumab to Treat Systemic Lupus Erythematosus in Pediatric Participants

A Study to evaluate the PK, PD, efficacy, and safety of Anifrolumab in children with moderate to severe active SLE...

Los Angeles, CAPHASE3100 participantsAstraZeneca

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NCT05201469Recruiting

VIBRANT: VIB4920 for Active Lupus Nephritis

This is a multi-center double-blind placebo controlled clinical trial evaluating the efficacy of VIB4920 combined with mycophenolate mofetil (MMF) and prednisone in achieving a renal response in parti...

Los Angeles, CAPHASE274 participantsNational Institute of Allergy and Infectious Diseases (NIAID)

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About Lupus Clinical Trials in Los Angeles

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, brain, and other organs. It is more common in women and often involves periods of flares and remission. Treatment includes antimalarials, immunosuppressants, and biologics.

There are currently 13 lupus clinical trials recruiting participants in Los Angeles, CA. These studies are seeking a combined 8,579 participants. Research is being sponsored by Lupus Research Alliance, Children's Hospital Los Angeles, AstraZeneca and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lupus Clinical Trials in Los Angeles — FAQ

Are there lupus clinical trials in Los Angeles?

Yes, there are 13 lupus clinical trials currently recruiting in Los Angeles, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What lupus treatments are being tested?

The 13 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for lupus.

Data updated October 17, 2026 from ClinicalTrials.gov