Los Angeles, CA10 Active Studies

Ulcerative Colitis Clinical Trials in Los Angeles, CA

Find 10 actively recruiting ulcerative colitis clinical trials in Los Angeles, CA. Connect with local research sites and explore new treatment options.

10
Active Trials
9
Sponsors
1,995
Enrolling

Recruiting Ulcerative Colitis Studies in Los Angeles

RecruitingLos Angeles, CANCT06052059

A Study to Evaluate Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderately to Severely Active Ulcerative Colitis (MK-7240-001)

The purpose of this protocol is to evaluate the efficacy of tulisokibart in participants with moderately to severely active ulcerative colitis. Study 1's primary hypotheses are that at least 1 tulisok...

1,020 participants
Merck Sharp & Dohme LLC
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RecruitingLos Angeles, CANCT06043440

Down Syndrome Obstructive Sleep Apnea

The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) w...

230 participants
Brigham and Women's Hospital
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RecruitingLos Angeles, CANCT06254950

A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Ulcerative Colitis

The main aim of this study is to learn if TAK-279 reduces bowel inflammation and symptoms compared to placebo. Another aim is to compare any medical problems that participants have when they take TAK-...

207 participants
Takeda
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RecruitingLos Angeles, CANCT04624230

Evaluation of Oral Tofacitinib in Children Aged 2 to 17 Years Old Suffering From Moderate to Severe Ulcerative Colitis

This study, A3921210 is designed to evaluate the efficacy, safety and pharmacokinetics (PK) of tofacitinib in pediatric participants with moderately to severely active UC. In the US and EU, patients w...

120 participants
Pfizer
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RecruitingLos Angeles, CANCT05076175

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining clinical remission. Ozanimod will be administered orally to pediatric participa...

120 participants
Bristol-Myers Squibb
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RecruitingLos Angeles, CANCT05111574

Using Nivolumab Alone or With Cabozantinib to Prevent Mucosal Melanoma Return After Surgery

This phase II trial tests whether nivolumab in combination with cabozantinib works in patients with mucosal melanoma. Immunotherapy with monoclonal antibodies, such as nivolumab, may help the body's i...

99 participants
National Cancer Institute (NCI)
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RecruitingLos Angeles, CANCT05874414

Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

This is an open-label, multicenter Phase 1b/2a study to evaluate safety, pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of GNS561 in combination with trametinib in Advanced KRAS Mutated Cho...

74 participants
Genfit
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RecruitingLos Angeles, CANCT06095128

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis (UC). Another aim...

65 participants
Takeda
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RecruitingLos Angeles, CANCT06138639

A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)

This is a multicenter, open-label, non-randomized study to investigate the safety, tolerability, and efficacy of a single intravenous (IV) infusion of SGT-003 in participants with Duchenne muscular dy...

40 participants
Solid Biosciences Inc.
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RecruitingLos Angeles, CANCT06053814

NS-050/NCNP-03 in Boys With DMD (Meteor50)

This is a Phase 1/2 study of Multiple-Ascending Dose (MAD) levels for 12 weeks of treatment followed by 24 weeks of open-label treatment with a selected dose of NS-050/NCNP-03 administered once weekly...

20 participants
NS Pharma, Inc.
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About Ulcerative Colitis Clinical Trials in Los Angeles

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 10 ulcerative colitis clinical trials recruiting participants in Los Angeles, CA. These studies are seeking a combined 1,995 participants. Research is being sponsored by Merck Sharp & Dohme LLC, Brigham and Women's Hospital, Takeda and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in Los Angeles — FAQ

Are there ulcerative colitis clinical trials in Los Angeles?

Yes, there are 10 ulcerative colitis clinical trials currently recruiting in Los Angeles, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Los Angeles?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Los Angeles research site will contact you about next steps.

Are clinical trials in Los Angeles free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Los Angeles studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 10 active trials in Los Angeles are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated March 2, 2026 from ClinicalTrials.gov