14 Multiple Myeloma Clinical Trials in Middletown, CT (2026)

Q: How do I join a clinical trial in Middletown?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Middletown research site will contact you.

Recruiting Multiple Myeloma Studies in Middletown

NCT05623020Recruiting

A Study to Learn About the Effects of the Combination of Elranatamab, Daratumumab and Lenalidomide Compared With Daratumumab, Bortezomib, Lenalidomide, and Dexamethasone in Patients With Newly Diagnosed Multiple Myeloma Who Are Not Candidates for Transplant

Elranatamab is a bispecific antibody: binding of elranatamab to CD3-expressing T-cells and BCMA-expressing multiple myeloma cells causes targeted T-cell-mediated cytotoxicity. The main purpose of the ...

Middletown, CT1,116 participantsPfizer

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NCT07226609Recruiting

A Dietary Study for People With Multiple Myeloma

The purpose of the study is to find out whether a dietary intervention can affect treatment response and/or quality of life for people with newly diagnosed multiple myeloma receiving standard inductio...

Middletown, CT220 participantsMemorial Sloan Kettering Cancer Center

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NCT06679829Recruiting

A Study of Melphalan With or Without Siltuximab in People With Multiple Myeloma Having an Autologous Stem Cell Transplant

The purpose of this study is to see if siltuximab plus population pharmacokinetic (PK)-dosed melphalan works as well as the usual approach (body surface area \[BSA\]-dosed melphalan) in people with mu...

Middletown, CT215 participantsMemorial Sloan Kettering Cancer Center

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NCT06055894Recruiting

A Study of a Plant-Based Diet and Dietary Supplements in People With Smoldering Multiple Myeloma (SMM) or Monoclonal Gammopathy of Undetermined Significance (MGUS)

The researchers are going this to look at how butyrate levels change in participants' stool after they are on a plant-based diet or dietary supplements (omega-3, curcumin or probiotics) for 2 weeks. A...

Middletown, CT200 participantsMemorial Sloan Kettering Cancer Center

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NCT05640843Recruiting

A Study Comparing a Plant-Based Diet With Supplements and Placebo in People With Monoclonal Gammopathy of Undetermined Significance (MGUS) or Smoldering Multiple Myeloma (SMM)

The researchers are doing this study to look at how butyrate levels change in participants' stool after they are on a- plant-based diet for at least 12 weeks. All participants will have monoclonal gam...

Middletown, CT180 participantsMemorial Sloan Kettering Cancer Center

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NCT06976476Recruiting

Study of IgPro20 to Prevent Infection in People With Multiple Myeloma and Hypogammaglobulinemia

The main purpose of this study is to see if IgPro20 can prevent infection in people with multiple myeloma (MM) who have hypogammaglobulinemia from receiving bispecific monoclonal antibodies (BsAbs)....

Middletown, CT100 participantsMemorial Sloan Kettering Cancer Center

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NCT06232044Recruiting

Testing the Combination of Two Approved Drugs and One Experimental Drug in Patients With Relapsed or Refractory Multiple Myeloma

This phase I/II trial tests the safety, side effects, best dose, and effectiveness of iberdomide in combination with belantamab mafodotin and dexamethasone in treating patients with multiple myeloma (...

Middletown, CT88 participantsAlliance for Clinical Trials in Oncology

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NCT07099391Recruiting

A Study of Dara-RVd and Teclistamab-RVd in People With Multiple Myeloma

The purpose of this study is to find out whether Tec-RVd (teclistamab, lenalidomide, bortezomib, and dexamethasone) after 3 treatment Cycles of Dara-RVd (daratumumab, lenalidomide, bortezomib, and dex...

Middletown, CT65 participantsMemorial Sloan Kettering Cancer Center

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NCT05787574Recruiting

A Study of Treatment of Inflammation Before Stem Cell Transplant in People With a Primary Immune Regulatory Disorder (PIRD) and/or an Autoinflammatory Condition

The researchers are doing this study to find out whether emapalumab or a combination of fludarabine and dexamethasone are effective in preparing people with a primary immune regulatory disorder (PIRD)...

Middletown, CT39 participantsMemorial Sloan Kettering Cancer Center

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NCT06873815Recruiting

A Study of Fluorescein Sodium in People Undergoing Vulvectomy for Extramammary Paget's Disease (EMPD)

The researchers are doing this study to see if giving people fluorescein sodium as an IV infusion before their vulvectomy for treating extramammary Paget's disease (EMPD) can help surgeons with perfor...

Middletown, CT27 participantsMemorial Sloan Kettering Cancer Center

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NCT07454382Recruiting

A Study of Elranatamab and Cyclophosphamide in People With Multiple Myeloma

The purpose of this study is to find out whether the combination of elranatamab and cyclophosphamide is an effective treatment for people with relapsed/refractory multiple myeloma (MM) who have risk f...

Middletown, CT26 participantsMemorial Sloan Kettering Cancer Center

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NCT06083922Recruiting

A Study of CyBorD (Cyclophosphamide, Bortezomib, Dexamethasone) Plus Daratumumab in People With Monoclonal Gammopathy of Renal Significance (MGRS)

The purpose of this study is to find out whether cyclophosphamide, bortezomib, dexamethasone (CyBorD) with daratumumab SC is a safe treatment combination for MGRS-associated kidney disease including c...

Middletown, CT20 participantsMemorial Sloan Kettering Cancer Center

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NCT07105059Recruiting

A Study of Teclistamab and Mezigdomide in People With Multiple Myeloma

The researchers are doing this study to find out whether combining teclistamab and mezigdomide is a safe and effective treatment approach in people with relapsed/refractory multiple myeloma (MM)....

Middletown, CT18 participantsMemorial Sloan Kettering Cancer Center

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NCT06066346Recruiting

A Study of Talquetamab for People with Multiple Myeloma Who Have Received BCMA CAR T-Cell Therapy

The researchers are doing this study to find out whether talquetamab is an effective treatment after BCMA CAR Tcell therapy for people with relapsed or refractory multiple myeloma. All participants in...

Middletown, CT17 participantsMemorial Sloan Kettering Cancer Center

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About Multiple Myeloma Clinical Trials in Middletown

Multiple myeloma is a cancer of plasma cells in the bone marrow that produce abnormal antibodies. It can cause bone damage, kidney problems, and immune deficiency. Treatments have advanced significantly with proteasome inhibitors, immunomodulatory drugs, and CAR-T cell therapy.

There are currently 14 multiple myeloma clinical trials recruiting participants in Middletown, CT. These studies are seeking a combined 2,331 participants. Research is being sponsored by Pfizer, Memorial Sloan Kettering Cancer Center, Alliance for Clinical Trials in Oncology. Clinical trial participation is free and participants receive study-related medical care at no cost.

Multiple Myeloma Clinical Trials in Middletown — FAQ

Are there multiple myeloma clinical trials in Middletown?

Yes, there are 14 multiple myeloma clinical trials currently recruiting in Middletown, CT. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Middletown?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Middletown research site will contact you about next steps.

Are clinical trials in Middletown free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Middletown studies also compensate for your time and travel.

What multiple myeloma treatments are being tested?

The 14 active trials in Middletown are testing new therapies including novel drugs, biologics, and treatment approaches for multiple myeloma.

Data updated July 13, 2026 from ClinicalTrials.gov