New York, NY30 Active Studies

Breast Cancer Clinical Trials in New York, NY

Find 30 actively recruiting breast cancer clinical trials in New York, NY. Connect with local research sites and explore new treatment options.

30
Active Trials
13
Sponsors
5,575
Enrolling

Recruiting Breast Cancer Studies in New York

RecruitingNew York, NYNCT06757634

Phase 3 Study of Gedatolisib as First-Line Treatment for Patients With HR-Positive, HER2-Negative Advanced Breast Cancer (VIKTORIA-2)

This is a Phase 3, open-label, randomized, clinical trial evaluating the efficacy and safety of gedatolisib plus fulvestrant and CDK4/6 Inhibitors for the treatment of patients with locally advanced o...

674 participants
Celcuity Inc
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RecruitingNew York, NYNCT01603316

Food: A Three-Arm Study Examining Food Insecurity Interventions

The investigators have found that many patients getting treatment for cancer have trouble getting enough to eat, or do not always have enough money for food. When a patient has these problems it can l...

668 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT03424005

A Study Evaluating the Efficacy and Safety of Multiple Treatment Combinations in Patients With Metastatic or Locally Advanced Breast Cancer

This is an umbrella study evaluating the efficacy and safety of multiple treatment combinations in participants with metastatic or inoperable locally advanced breast cancer. The study will be perform...

580 participants
Hoffmann-La Roche
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RecruitingNew York, NYNCT06075953

DCIS: RECAST Trial Ductal Carcinoma In Situ: Re-Evaluating Conditions for Active Surveillance Suitability as Treatment

The goal of this trial is to see if active surveillance monitoring and hormonal therapy in patients diagnosed with ductal cell carcinoma in situ (DCIS), an early stage of breast cancer, can be an effe...

400 participants
QuantumLeap Healthcare Collaborative
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RecruitingNew York, NYNCT06960707

Two Versus One Week Breast Radiotherapy (RT)

This study is comparing two different radiation therapy approaches for early breast cancer to see which one is better for patients. One group will receive radiation over one week (based on the FAST-FO...

400 participants
Weill Medical College of Cornell University
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RecruitingNew York, NYNCT06144164

A Study of a Comprehensive Prevention Program to Reduce Lymphedema After Axillary Lymph Node Dissection in People With Breast Cancer

The purpose of this study to test whether a comprehensive program may help the lymph fluid to drain out of the arm and prevent lymphedema in participants with breast cancer....

285 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT06726148

Study of ECI830 Single Agent or in Combination in Patients With Advanced HR+/HER2- Breast Cancer and Other Advanced Solid Tumors

Phase I: Characterize safety and tolerability of ECI830 as a single agent and in combination with ribociclib and fulvestrant. Identify dose range for optimization/recommended dose for future studies. ...

280 participants
Novartis Pharmaceuticals
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RecruitingNew York, NYNCT04084730

Study of 3-Day Partial Breast Radiation Therapy in Women With Breast Cancer

The purpose of this study is to determine if the dose of radiation therapy that is effective in producing a treatment response, delivered over a shorter treatment period, is a safe approach that cause...

280 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT05856773

Conventionally Fractionated vs. Hypofractionated Comprehensive Nodal Irradiation for Breast Cancer Using Pencil Beam Scanning Proton Therapy

The purpose of this research study is to learn more about the effects of using proton radiation therapy delivered over a shorter course of treatment (3 weeks) compared with a longer, standard course o...

276 participants
Proton Collaborative Group
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RecruitingNew York, NYNCT06099769

A Study of Enzalutamide, Enzalutamide in Combination With Mifepristone, or Chemotherapy in People With Metastatic Breast Cancer

The researchers are doing this study to find out if the study drug, enzalutamide, alone or combined with the study drug, mifepristone, is effective in treating advanced or metastatic androgen receptor...

201 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT06172127

PHESGO Maintenance After T-DXd Short Induction for HER2+ Unresectable Locally Recurrent or Metastatic Breast Cancer

DEMETHER is a phase II trial exploring the maintenance of trastuzumab and pertuzumab fixed dose combination (FDC) for subcutaneous administration (SC, PHESGO) following trastuzumab deruxtecan (T-DXd) ...

165 participants
MedSIR
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RecruitingNew York, NYNCT03351348

Bupivacaine vs Placebo for Unilateral Mastectomy Surgical Site Post-operative Pain Control

The purpose of this study is to compare using FDA-approved bupivacaine (a numbing medicine), along with the usual medications for post-operative pain control to using the usual medications for postope...

165 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT07053085

A Study of Surgery and Radiotherapy in People With Breast Cancer

The researchers are doing this study to see if the combination of surgery, locoregional radiation therapy, SBRT (stereotactic body radiation therapy), and the usual approach is more effective in treat...

162 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT05716893

Study of Aerobic Training for People Receiving Chemotherapy for Breast Cancer

In this study, investigators will compare standard Aerobic Training/AT with adaptive Aerobic Training/AT. Standard AT will be a fixed (unchanging) amount of walking each week, while adaptive AT will a...

140 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT01766297

Phase II Protocol of Proton Therapy for Partial Breast Irradiation in Early Stage Breast Cancer

The purpose of this research study is to compare the effects (good and bad) on women and their cancer using proton radiation therapy. This study is being done to see if proton radiation therapy will ...

132 participants
Proton Collaborative Group
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RecruitingNew York, NYNCT04563507

Combined Immunotherapies in Metastatic ER+ Breast Cancer

Women with Hormone Receptor (HR)+ Human Epidermal growth factor Receptor (HER)2- metastatic breast cancer are eligible to a randomized trial. Patients receiving standard first line therapy for metasta...

102 participants
Weill Medical College of Cornell University
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RecruitingNew York, NYNCT03804944

Converting HR+ Breast Cancer Into an Individualized Vaccine

Newly diagnosed post-menopausal women with clinical stage II-III, HR+HER2- breast cancer are eligible to a randomized trial, concurrently open at five US academic institutions. Patients receiving 4 mo...

100 participants
Weill Medical College of Cornell University
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RecruitingNew York, NYNCT06840483

Study of Zelenectide Pevedotin in Participants With Advanced Breast Cancer

This is a global, multicenter, open-label study that aims to assess the efficacy and safety of zelenectide pevedotin in participants with NECTIN4-amplified recurrent, unresectable, or metastatic breas...

66 participants
BicycleTx Limited
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RecruitingNew York, NYNCT07042581

A Study of Revaree Plus in People With Breast Cancer

The purpose of this study is to find out whether Revaree Plus is effective at improving vaginal health for people who are having symptoms of vaginal dryness during breast cancer treatment....

60 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT05130801

A Study of Multiparametric MRI and pHLIP® ICG in Breast Cancer Imaging During Surgery

The purpose of this study is to find out whether pre-operative mpMRI using additional MRI sequences may improve surgical outcomes by providing more accurate information about the extent and acidity of...

55 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT05570253

A Study of SDX-7320 in Combination With Eribulin for People With Breast Cancer

The researchers are doing this study to find out whether the study drug, SDX-7320, when combined with the standard chemotherapy eribulin, is an effective treatment for people with TNBC and metabolic d...

55 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT06110793

A Study of Lenvatinib, Pembrolizumab, and Fulvestrant in People With Breast Cancer

The purpose of this study is to test whether the combination of lenvatinib, pembrolizumab, and fulvestrant is a safe and effective treatment that causes few or mild side effects in people with ER+/HER...

43 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT05095207

Abemaciclib in Combination With Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer

This is an open label multicenter, Phase IB/II Study of Abemaciclib in Combination with Bicalutamide for Androgen Receptor-positive, HER2-negative Metastatic Breast Cancer...

42 participants
Icahn School of Medicine at Mount Sinai
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RecruitingNew York, NYNCT04711824

Study of Stereotactic Radiosurgery With Olaparib Followed by Durvalumab and Physician's Choice Systemic Therapy in Subjects With Breast Cancer Brain Metastases

This study is a Phase I/II study evaluating the safety and effectiveness of focused radiation therapy (radiosurgery) together with olaparib, followed by immunotherapy, for patients with brain metastas...

41 participants
Colette Shen
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RecruitingNew York, NYNCT03449238

Pembrolizumab And Stereotactic Radiosurgery (Srs) Of Selected Brain Metastases In Breast Cancer Patients

Patients with metastatic breast cancer with at least 2 brain metastases will receive pembrolizumab every 3 weeks. Patients will undergo stereotactic radiosurgery (SRS) to one of the brain lesions. Pem...

41 participants
Weill Medical College of Cornell University
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RecruitingNew York, NYNCT05534438

A Study on Adding Precisely Targeted Radiation Therapy (Stereotactic Body Radiation Therapy) to the Usual Treatment Approach (Drug Therapy) in People With Breast Cancer

The purpose of this study is to see if using Stereotactic Body Radiation Therapy/SBRT to treat a single metastatic site where cancer has worsened may be an effective treatment for people with oligomet...

40 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT04683679

A Study of Radiation Therapy With Pembrolizumab and Olaparib or Other Radiosensitizers in Women Who Have Triple-Negative or Hormone-Receptor Positive/Her2 Negative Breast Cancer

The purpose of this study is to find out whether adding pembrolizumab, with or without olaparib, to standard radiation therapy is a safe and effective treatment for metastatic breast cancer, , and to ...

34 participants
Memorial Sloan Kettering Cancer Center
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RecruitingNew York, NYNCT04092673

Study of eFT226 in Subjects With Selected Advanced Solid Tumor Malignancies

This clinical trial is a Phase 1-2, open-label, sequential-group, dose-escalation and cohort-expansion study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and antitumor activity of Z...

30 participants
Effector Therapeutics
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RecruitingNew York, NYNCT03990896

Evaluation of Talazoparib, a PARP Inhibitor, in Patients With Somatic BRCA Mutant Metastatic Breast Cancer: Genotyping Based Clinical Trial

This research is to evaluate the effectiveness of Talazoparib as a potential treatment for metastatic breast cancer with a BRCA 1 or BRCA 2 mutation....

30 participants
Massachusetts General Hospital
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RecruitingNew York, NYNCT05892068

A Study of Tucatinib Given Before Surgery to People With HER2+ Cancers That Have Spread to the Brain

The purpose of this study to see how the brain absorbs, distributes, and gets rid of tucatinib in people who have HER2+ cancers (breast cancer, NSCLC, CRC, or GEC) that have spread to the brain, and t...

28 participants
Memorial Sloan Kettering Cancer Center
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About Breast Cancer Clinical Trials in New York

Breast cancer is a disease in which cells in the breast grow out of control. It is the most common cancer in women worldwide and can also occur in men. Treatment options include surgery, radiation, chemotherapy, hormone therapy, and targeted therapies.

There are currently 30 breast cancer clinical trials recruiting participants in New York, NY. These studies are seeking a combined 5,575 participants. Research is being sponsored by Celcuity Inc, Memorial Sloan Kettering Cancer Center, Hoffmann-La Roche and 10 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Breast Cancer Clinical Trials in New York — FAQ

Are there breast cancer clinical trials in New York?

Yes, there are 30 breast cancer clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What breast cancer treatments are being tested?

The 30 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for breast cancer.

Data updated March 2, 2026 from ClinicalTrials.gov