19 Sarcoma Clinical Trials in New York, NY (2026)

Q: How do I join a clinical trial in New York?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you.

Recruiting Sarcoma Studies in New York

NCT01109394Recruiting

Comprehensive Omics Analysis of Pediatric and Adult Solid Tumors and Establishment of a Repository for Related Biological Studies

Background: \- Laboratory investigators who are studying common childhood cancers are interested in developing a tissue repository to collect and store blood, serum, tissue, urine, or tumors of child...

New York, NY6,035 participantsNational Cancer Institute (NCI)

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NCT00579566Recruiting

Novel Biochemical and Molecular Determinants for Soft Tissue Sarcoma

The purpose of this study is to study normal and sarcoma cells. To study these cells we need to have human tissue. You will be having or have already had a procedure to remove tissue. We would like to...

New York, NY3,000 participantsMemorial Sloan Kettering Cancer Center

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NCT03442465Recruiting

Assessment of Healing and Function After Reconstruction Surgery for Bone Sarcomas

The purpose of this study is to look at the amount of function that returns in participants that have reconstruction with bone graft or artificial device and in participants who have tumor surgery plu...

New York, NY300 participantsMemorial Sloan Kettering Cancer Center

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NCT06797999Recruiting

First-in-Human Study of ADCE-D01 in Soft Tissue Sarcoma

The goal of this clinical trial is to learn about the safety, tolerability and efficacy of ADCE-D01....

New York, NYPHASE1270 participantsAdcendo ApS

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NCT05653388Recruiting

Metastatic Leiomyosarcoma Biomarker Protocol

Leiomyosarcoma (LMS) is one of the most prevalent soft tissue sarcomas (STS) and can occur in various sites including soft tissue, uterus and retroperitoneal large vessels. Metastatic disease occurs i...

New York, NY200 participantsUniversity of Michigan Rogel Cancer Center

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NCT04577014Recruiting

Retifanlimab (Anti-PD-1 Antibody) With Gemcitabine and Docetaxel in Patients With Advanced Soft Tissue Sarcoma

This study is being done to find out whether the study drug Retifanlimab, a monoclonal antibody against the PD-1 protein, combined with gemcitabine and docetaxel, is a safe and effective treatment for...

New York, NYPHASE198 participantsMemorial Sloan Kettering Cancer Center

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NCT06021626Recruiting

A Study of CRD3874-SI in People With Solid Tumors

This study will test the safety of a study drug called CRD3874-SI. The researchers will test different doses of CRD3874-SI to find the highest dose that causes few or mild side effects in participants...

New York, NYPHASE181 participantsMemorial Sloan Kettering Cancer Center

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NCT05918640Recruiting

Lurbinectedin in FET-Fused Tumors

The purpose of this study is to find out if a drug called lurbinectedin (the "study drug") is safe and effective at treating people with recurrent or relapsed solid tumors, including Ewing sarcoma....

New York, NYPHASE163 participantsChildren's Hospital of Philadelphia

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NCT05734066Recruiting

Study of Lurbinectedin Monotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Ewing Sarcoma

This study is conducted in two phases. The phase 1 portion of the study evaluates the safety, tolerability, pharmacokinetics (PK), recommended phase 2 dose (RP2D), and effectiveness of lurbinectedin m...

New York, NYPHASE160 participantsJazz Pharmaceuticals

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NCT06129903Recruiting

Study Assessing the Effects of Early Psychiatric Referral on Mental Health and Quality of Life in People With Sarcoma

The purpose of this study is to investigate the feasibility of early access to mental healthcare during sarcoma treatment as well as to assess the association between early access to psychiatric care ...

New York, NYNA60 participantsMemorial Sloan Kettering Cancer Center

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NCT06843967Recruiting

A Study of Mirdametinib in Combination With Palbociclib in People With Liposarcoma

The purpose of this study is to find out whether mirdametinib in combination with palbociclib is an effective and safe treatment for people with metastatic, recurrent, and unresectable liposarcoma. Th...

New York, NYPHASE154 participantsMemorial Sloan Kettering Cancer Center

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NCT07297979Recruiting

Evaluation of Xaluritamig in Adults, Adolescents and Children With Relapsed or Refractory Ewing Sarcoma (EWS)

The main objectives of this trial are to determine the recommended dose for expansion of xaluritamig (dose confirmation part only) and to determine the safety and tolerability of xaluritamig in adult,...

New York, NYPHASE150 participantsAmgen

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NCT07477457Recruiting

A Study of Gefitinib, Trametinib, Disulfiram, and Sunitinib in Addition to Standard Chemotherapy in People With Osteosarcoma

The researchers are doing this study to find out whether adding gefitinib, trametinib, disulfiram, and sunitinib to standard chemotherapy is a more effective treatment approach for people with osteosa...

New York, NYPHASE245 participantsMemorial Sloan Kettering Cancer Center

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NCT04305691Recruiting

Trial of Ixazomib for Kaposi Sarcoma

This phase II trial studies how well ixazomib works in treating patients with Kaposi sarcoma. Ixazomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth....

New York, NYPHASE241 participantsAIDS Malignancy Consortium

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NCT05755113Recruiting

A Clinical Study to Investigate the Efficacy of Intratumoral Tigilanol Tiglate in Soft Tissue Sarcoma

A Phase IIa open label study evaluating the preliminary efficacy of intratumoural tigilanol tiglate in advanced and/or metastatic soft tissue sarcoma of the extremities and body wall....

New York, NYPHASE240 participantsQBiotics Group Limited

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NCT07089992Recruiting

A Study of Pembrolizumab in People With Ultra-Rare Sarcomas

The purpose of the study is to find out if pembrolizumab is a useful treatment that causes few or mild side effects in people with ultra-rare sarcoma. The researchers will also study how the immune sy...

New York, NYPHASE232 participantsMemorial Sloan Kettering Cancer Center

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NCT07156565Recruiting

Actinium Therapy for Late-stage Aggressive Sarcomas

The goal of this clinical trial is to learn about the safety of drug \[Ac225\]RTX-2358 and the diagnostic imaging agent \[Cu64\]LNTH-1363S. Additionally Ratio Therapeutics will learn if \[Ac225\]RTX-2...

New York, NYPHASE130 participantsRatio Therapeutics, Inc.

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NCT04332874Recruiting

A Study of Pembrolizumab Plus Local Chemotherapy Using Isolated Limb Infusion (ILI) for Patients With Sarcoma in the Arm or Leg

The purpose of this study is to find out whether giving the study drug pembrolizumab in combination with the chemotherapy drugs melphalan and dactinomycin, delivered directly to the affected arm or le...

New York, NYPHASE230 participantsMemorial Sloan Kettering Cancer Center

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NCT07516925Recruiting

A Study of Ivonescimab in People With Leiomyosarcoma

The purpose of this study is to find out if Ivonescimab is an effective and safe treatment that causes few or mild side effects for people with advanced/unresectable leiomyosarcoma....

New York, NYPHASE220 participantsMemorial Sloan Kettering Cancer Center

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About Sarcoma Clinical Trials in New York

Sarcomas are rare cancers that arise in bone and soft tissues including muscle, fat, blood vessels, and connective tissue. There are more than 70 subtypes of sarcoma. Treatment usually involves surgery combined with radiation and/or chemotherapy.

There are currently 19 sarcoma clinical trials recruiting participants in New York, NY. These studies are seeking a combined 10,509 participants. Research is being sponsored by National Cancer Institute (NCI), Memorial Sloan Kettering Cancer Center, Adcendo ApS and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Sarcoma Clinical Trials in New York — FAQ

Are there sarcoma clinical trials in New York?

Yes, there are 19 sarcoma clinical trials currently recruiting in New York, NY. Browse the studies on this page to find one that fits.

How do I join a clinical trial in New York?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the New York research site will contact you about next steps.

Are clinical trials in New York free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many New York studies also compensate for your time and travel.

What sarcoma treatments are being tested?

The 19 active trials in New York are testing new therapies including novel drugs, biologics, and treatment approaches for sarcoma.

Data updated July 16, 2026 from ClinicalTrials.gov