Orange, CA5 Active Studies

Colorectal Cancer Clinical Trials in Orange, CA

Find 5 actively recruiting colorectal cancer clinical trials in Orange, CA. Connect with local research sites and explore new treatment options.

5
Active Trials
5
Sponsors
1,025
Enrolling

Recruiting Colorectal Cancer Studies in Orange

RecruitingOrange, CANCT05673148

Testing the Addition of Total Ablative Therapy to Usual Systemic Therapy Treatment for Limited Metastatic Colorectal Cancer, The ERASur Study

This phase III trial compares total ablative therapy and usual systemic therapy to usual systemic therapy alone in treating patients with colorectal cancer that has spread to up to 4 body sites (limit...

364 participants
Alliance for Clinical Trials in Oncology
View Study Details
RecruitingOrange, CANCT04486378

A Phase II Clinical Trial Comparing the Efficacy of RO7198457 Versus Watchful Waiting in Patients With ctDNA-positive, Resected Stage II (High Risk) and Stage III Colorectal Cancer

This is a multi-site, open-label, Phase II, randomized, trial to compare the efficacy of RO7198457 versus watchful waiting in patients with circulating tumor DNA (ctDNA) positive, surgically resected ...

327 participants
BioNTech SE
View Study Details
RecruitingOrange, CANCT06205485

Neoadjuvant Chemotherapy, Excision And Observation vs Chemoradiotherapy For Rectal Cancer

This study is being done to answer the following questions: Is the chance of rectal cancer responding the same if chemotherapy alone is given before limited surgery compared to chemotherapy and radiat...

250 participants
Canadian Cancer Trials Group
View Study Details
RecruitingOrange, CANCT03516708

Epacadostat (INCB024360) Added to Preoperative Chemoradiation in Patients With Locally Advanced Rectal Cancer

The purpose of this research study is to evaluate epacadostat when given with routine radiation therapy and chemotherapy (capecitabine and oxaliplatin) to treat rectal cancer before routine surgery is...

49 participants
Washington University School of Medicine
View Study Details
RecruitingOrange, CANCT06730100

CBX-12 for the Treatment of Metastatic Chemotherapy-Refractory Microsatellite Stable Colorectal Cancer

This phase II trial studies how well CBX-12 works in treating patients with microsatellite stable colorectal cancer that has spread to other parts of the body (metastatic) and is no longer responding ...

35 participants
National Cancer Institute (NCI)
View Study Details

About Colorectal Cancer Clinical Trials in Orange

Colorectal cancer starts in the colon or rectum and is the third most common cancer diagnosed in both men and women. Early detection through screening significantly improves outcomes. Treatments include surgery, chemotherapy, radiation, and targeted therapies.

There are currently 5 colorectal cancer clinical trials recruiting participants in Orange, CA. These studies are seeking a combined 1,025 participants. Research is being sponsored by Alliance for Clinical Trials in Oncology, BioNTech SE, Canadian Cancer Trials Group and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Colorectal Cancer Clinical Trials in Orange — FAQ

Are there colorectal cancer clinical trials in Orange?

Yes, there are 5 colorectal cancer clinical trials currently recruiting in Orange, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orange?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.

Are clinical trials in Orange free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.

What colorectal cancer treatments are being tested?

The 5 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for colorectal cancer.

Data updated March 2, 2026 from ClinicalTrials.gov