Recruiting Melanoma Studies in Orange
A Study With Combinations of Anti-LAG-3 and Anti-PD-1 Antibodies in Adult Participants With Advanced or Metastatic Melanoma (Harmony Head-to-Head)
This study is researching an experimental drug called fianlimab (also known as REGN3767), combined with another medication called cemiplimab (also known as REGN2810), called "study drugs". The study i...
Neoadjuvant Darovasertib in Primary Uveal Melanoma
This is a Phase 3, randomized, multi-center, open-label study of neoadjuvant darovasertib in subjects with primary non-metastatic uveal melanoma (OptimUM-10)...
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]
This is a randomized, controlled, multicenter, open-label Phase 3 clinical study comparing VO in combination with nivolumab versus Physician's Choice treatment for patients with unresectable Stage III...
Efficacy of Daromun Neoadjuvant Intratumoral Treatment in Clinical Stage IIIB/C Melanoma Patients
The trial aims to evaluate the efficacy of Daromun neoadjuvant treatment followed by surgery and adjuvant therapy to improve in a statistically significant manner the recurrence-free survival (RFS) of...
BiCaZO: A Study Combining Two Immunotherapies (Cabozantinib and Nivolumab) to Treat Patients With Advanced Melanoma or Squamous Cell Head and Neck Cancer, an immunoMATCH Pilot Study
This phase II trial studies the good and bad effects of the combination of drugs called cabozantinib and nivolumab in treating patients with melanoma or squamous cell head and neck cancer that may hav...
About Melanoma Clinical Trials in Orange
Melanoma is the most serious type of skin cancer, developing from the pigment-producing cells known as melanocytes. While less common than other skin cancers, melanoma is more likely to spread. Immunotherapy and targeted therapy have revolutionized melanoma treatment.
There are currently 5 melanoma clinical trials recruiting participants in Orange, CA. These studies are seeking a combined 1,816 participants. Research is being sponsored by Regeneron Pharmaceuticals, IDEAYA Biosciences, Replimune Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.
Melanoma Clinical Trials in Orange — FAQ
Are there melanoma clinical trials in Orange?
Yes, there are 5 melanoma clinical trials currently recruiting in Orange, CA. Browse the studies on this page to find one that fits.
How do I join a clinical trial in Orange?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.
Are clinical trials in Orange free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.
What melanoma treatments are being tested?
The 5 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for melanoma.
Data updated March 2, 2026 from ClinicalTrials.gov