5 Diffuse Large B-Cell Lymphoma Clinical Trials in Orange, CA (2026)

Q: How do I join a clinical trial in Orange?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you.

Recruiting Diffuse Large B-Cell Lymphoma Studies in Orange

NCT06091865Recruiting

A Study to Compare How Well Odronextamab Combined With Chemotherapy Works and How Safe it is Against Rituximab Combined With Chemotherapy, in Adult Patients With Previously Untreated Diffuse Large B-cell Lymphoma

This study is researching an experimental drug called odronextamab, referred to as study drug, when used in combination with chemotherapy. The study is focused on patients with Diffuse Large B-cell Ly...

Orange, CAPHASE3904 participantsRegeneron Pharmaceuticals

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NCT07188558Recruiting

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

This Phase 3 study compares rondecabtagene autoleucel (ronde-cel), a dual-targeting CD19/CD20 CAR T-cell therapy, with investigator's choice of CD19 CAR T-cell therapy in patients with relapsed or ref...

Orange, CAPHASE3400 participantsLyell Immunopharma, Inc.

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NCT05633615Recruiting

Testing Drug Treatments After CAR T-cell Therapy in Patients With Relapsed/Refractory Diffuse Large B-cell Lymphoma

This phase II trial tests whether mosunetuzumab and/or polatuzumab vedotin helps benefit patients who have received chemotherapy (fludarabine and cyclophosphamide) followed by chimeric antigen recepto...

Orange, CAPHASE2396 participantsSWOG Cancer Research Network

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NCT05952024Recruiting

Study of Acalabrutinib and Rituximab in Untreated Elderly and/or Frail Patients With DLBCL

The study will measure the safety, tolerability, and efficacy with acalabrutinib in combination with rituximab in treatment-naïve elderly and/or frail patients with diffuse large B-cell lymphoma (DLBC...

Orange, CAPHASE280 participantsAstraZeneca

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NCT05905328Recruiting

Study of CTO1681 for the Prevention and Treatment of CRS in DLBCL Patients Receiving CAR T-Cell Therapy

This is an interventional study to evaluate the use of CTO1681 in preventing or reducing CAR T-cell-induced toxicities like cytokine release syndrome (CRS). This study will enroll adult patients with ...

Orange, CAPHASE154 participantsCytoAgents, Inc.

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About Diffuse Large B-Cell Lymphoma Clinical Trials in Orange

Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma, accounting for about 30% of cases. It is an aggressive lymphoma that grows rapidly. Treatment usually involves chemoimmunotherapy, with CAR-T cell therapy for relapsed cases.

There are currently 5 diffuse large b-cell lymphoma clinical trials recruiting participants in Orange, CA. These studies are seeking a combined 1,834 participants. Research is being sponsored by Regeneron Pharmaceuticals, Lyell Immunopharma, Inc., SWOG Cancer Research Network and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Diffuse Large B-Cell Lymphoma Clinical Trials in Orange — FAQ

Are there diffuse large b-cell lymphoma clinical trials in Orange?

Yes, there are 5 diffuse large b-cell lymphoma clinical trials currently recruiting in Orange, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orange?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.

Are clinical trials in Orange free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.

What diffuse large b-cell lymphoma treatments are being tested?

The 5 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for diffuse large b-cell lymphoma.

Data updated October 16, 2026 from ClinicalTrials.gov