6 Bipolar Disorder Clinical Trials in Orange, FL (2026)

Q: How do I join a clinical trial in Orange?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you.

Recruiting Bipolar Disorder Studies in Orange

NCT07140913Recruiting

A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine

The purpose of this study is to evaluate the efficacy and safety of adjunctive KarXT for the treatment of mania in participants with Bipolar-I Disorder....

Orange, FLPHASE3424 participantsBristol-Myers Squibb

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NCT07172516Recruiting

A Randomized Study of Azetukalner Versus Placebo in Depressive Episodes Associated With Bipolar I or II Disorder (Bipolar Depression)

X-CEED is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of azetukalner in adult participants diagnosed with bipolar I or II disorder wh...

Orange, FLPHASE3400 participantsXenon Pharmaceuticals Inc.

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NCT07286175Recruiting

A Study of Brenipatide in Adult Participants With Bipolar Disorder (RENEW-Bipolar-1)

The purpose of this study is to assess the efficacy and safety of brenipatide when administered with standard of care (SoC), compared with placebo plus SoC in delaying the worsening of bipolar disorde...

Orange, FLPHASE2400 participantsEli Lilly and Company

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NCT04777357Recruiting

A Study to Assess Change in Disease Activity and Adverse Events (AEs) With Cariprazine in the Treatment of Depressive Episodes in Pediatric Participants Participants (10 to 17 Years of Age) With Bipolar I Disorder.

Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. The treatment of the depressive episodes of ...

Orange, FLPHASE3380 participantsAbbVie

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NCT07494305Recruiting

Multicenter Study to Assess the Efficacy and Safety of LB-102 in the Treatment of Adult Patients With BP1MDE.

Phase II study for patients with Bipolar 1 Disorder experiencing major depressive episode. Patient eligible for enrollment will be randomized (like flipping a coin) to either active drug (LB-102 or pl...

Orange, FLPHASE2320 participantsLB Pharmaceuticals Inc.

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NCT06696755Recruiting

A Study to Assess Adverse Events and Change in Disease Activity of Oral Icalcaprant in Adult Participants With Bipolar I or II Disorder

Bipolar disorder is a severe chronic mood disorder that affects up to 4% of the adult population and 1.8% of the pediatric population in the United States. This study will assess how safe and effectiv...

Orange, FLPHASE2195 participantsAbbVie

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About Bipolar Disorder Clinical Trials in Orange

Bipolar disorder is a mental health condition marked by extreme mood swings including emotional highs (mania or hypomania) and lows (depression). It affects about 2.8% of adults in the U.S. Treatment typically involves mood stabilizers, antipsychotics, and psychotherapy.

There are currently 6 bipolar disorder clinical trials recruiting participants in Orange, FL. These studies are seeking a combined 2,119 participants. Research is being sponsored by Bristol-Myers Squibb, Xenon Pharmaceuticals Inc., Eli Lilly and Company and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Bipolar Disorder Clinical Trials in Orange — FAQ

Are there bipolar disorder clinical trials in Orange?

Yes, there are 6 bipolar disorder clinical trials currently recruiting in Orange, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orange?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.

Are clinical trials in Orange free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.

What bipolar disorder treatments are being tested?

The 6 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for bipolar disorder.

Data updated September 1, 2026 from ClinicalTrials.gov