Orange, FL7 Active Studies

Depression Clinical Trials in Orange, FL

Find 7 actively recruiting depression clinical trials in Orange, FL. Connect with local research sites and explore new treatment options.

7
Active Trials
6
Sponsors
2,469
Enrolling

Recruiting Depression Studies in Orange

RecruitingOrange, FLNCT06966401

Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

This study will evaluate the long-term safety and tolerability of NBI-1065845 as an adjunctive treatment in participants with MDD....

600 participants
Neurocrine Biosciences
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RecruitingOrange, FLNCT05711940

Efficacy, Safety, and Tolerability of Two Administrations of COMP360 in Participants With TRD

Efficacy, Safety, and Tolerability of two administrations of COMP360 in participants with treatment-resistant depression (TRD)...

568 participants
COMPASS Pathways
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RecruitingOrange, FLNCT06775379

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

X-NOVA2 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy in adult participants ...

450 participants
Xenon Pharmaceuticals Inc.
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RecruitingOrange, FLNCT06058013

Study to Assess the Effects of Oral NMRA-335140 Versus Placebo in Participants With Major Depressive Disorder

This is a randomized, double-blind, placebo-controlled, multicenter study to evaluate the effects of NMRA-335140 (formerly BTRX-335140) on symptoms of depression in participants with Major Depressive ...

332 participants
Neumora Therapeutics, Inc.
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RecruitingOrange, FLNCT06786624

Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)

The study will evaluate the efficacy of NBI-1065845 compared with placebo as an adjunctive treatment in participants with MDD on improving symptoms of depression....

200 participants
Neurocrine Biosciences
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RecruitingOrange, FLNCT06836063

Study to Evaluate Efficacy and Safety of Ropanicant in MDD Patients

The primary objective is to evaluate the efficacy of Ropanicant at two different dosage levels compared to placebo in patients with Major Depressive Disorder (MDD)....

195 participants
Suven Life Sciences Limited
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RecruitingOrange, FLNCT06785012

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

The purpose of this study is to evaluate how well JNJ-89495120 works (anti-depressant effects) and how well it is tolerated as compared to placebo on reducing the symptoms of depression in participant...

124 participants
Janssen Research & Development, LLC
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About Depression Clinical Trials in Orange

Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.

There are currently 7 depression clinical trials recruiting participants in Orange, FL. These studies are seeking a combined 2,469 participants. Research is being sponsored by Neurocrine Biosciences, COMPASS Pathways, Xenon Pharmaceuticals Inc. and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Depression Clinical Trials in Orange — FAQ

Are there depression clinical trials in Orange?

Yes, there are 7 depression clinical trials currently recruiting in Orange, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orange?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orange research site will contact you about next steps.

Are clinical trials in Orange free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orange studies also compensate for your time and travel.

What depression treatments are being tested?

The 7 active trials in Orange are testing new therapies including novel drugs, biologics, and treatment approaches for depression.

Data updated March 2, 2026 from ClinicalTrials.gov