5 Lupus Clinical Trials in Orlando, FL (2026)

Q: How do I join a clinical trial in Orlando?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you.

Recruiting Lupus Studies in Orlando

NCT05268289Recruiting

Study of Efficacy and Safety of LNP023 in Participants With Active Lupus Nephritis Class III-IV, +/- V

The overall purpose of this two-part study is to evaluate the efficacy, safety and tolerability of iptacopan (LNP023) in addition to standard of care treatment....

Orlando, FLPHASE2240 participantsNovartis Pharmaceuticals

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NCT07611214Recruiting

PRESERVE: LUPKYNIS in Combination With Belimumab, Obinutuzumab or Anifrolumab in Patients With Lupus Nephritis

The goal of this clinical study is to assess the efficacy and safety of LUPKYNIS® in combination with belimumab, obinutuzumab or anifrolumab at inducing rapid renal response in patients with lupus nep...

Orlando, FLPHASE4150 participantsAurinia Pharmaceuticals Inc.

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NCT06625671Recruiting

A Phase 1/2a Study of DB-2304 in Healthy Adults and SLE/CLE Participants

A Phase 1/2a Study of DB-2304 in Healthy Participants and Participants with Systemic Lupus Erythematosus or Cutaneous Lupus Erythematosus...

Orlando, FLPHASE1148 participantsDualityBio Inc.

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NCT07015983Recruiting

A Study of CC-97540 (BMS-986353), CD19-Targeted NEX-T CAR T Cells, in Participants With Active SLE Despite Immunosuppressants (Breakfree-SLE)

The purpose of this study is to evaluate the efficacy, safety and drug levels of CC-97540 in participants with active systemic lupus erythematosus (SLE) including lupus nephritis with inadequate respo...

Orlando, FLPHASE289 participantsJuno Therapeutics, Inc., a Bristol-Myers Squibb Company

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NCT06613360Recruiting

A Study of CLN-978, a Subcutaneously Administered CD19-directed T Cell Engager, in Subjects With Systemic Lupus Erythematosus

Phase 1b, open-label study of CLN-978 administered subcutaneously in patients with Moderate to Severe Systemic Lupus Erythematosus (SLE)....

Orlando, FLPHASE124 participantsCullinan Therapeutics Inc.

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About Lupus Clinical Trials in Orlando

Systemic lupus erythematosus (SLE) is a chronic autoimmune disease that can affect the joints, skin, kidneys, brain, and other organs. It is more common in women and often involves periods of flares and remission. Treatment includes antimalarials, immunosuppressants, and biologics.

There are currently 5 lupus clinical trials recruiting participants in Orlando, FL. These studies are seeking a combined 651 participants. Research is being sponsored by Novartis Pharmaceuticals, Aurinia Pharmaceuticals Inc., DualityBio Inc. and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lupus Clinical Trials in Orlando — FAQ

Are there lupus clinical trials in Orlando?

Yes, there are 5 lupus clinical trials currently recruiting in Orlando, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orlando?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you about next steps.

Are clinical trials in Orlando free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orlando studies also compensate for your time and travel.

What lupus treatments are being tested?

The 5 active trials in Orlando are testing new therapies including novel drugs, biologics, and treatment approaches for lupus.

Data updated July 19, 2026 from ClinicalTrials.gov