14 Ulcerative Colitis Clinical Trials in Orlando, FL (2026)

Q: How do I join a clinical trial in Orlando?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you.

Recruiting Ulcerative Colitis Studies in Orlando

NCT06586515Recruiting

MOONRAY-01, A Study of LY3962673 in Participants With KRAS G12D-Mutant Solid Tumors

The main purpose of this study is to assess safety \& tolerability and antitumor activity of LY3962673 as monotherapy and in combination with other chemotherapy agents in participants with KRAS G12D-m...

Orlando, FLPHASE1630 participantsEli Lilly and Company

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NCT06937086Recruiting

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

The main purpose of this study is to show whether in these individuals, treatment with both mirikizumab and tirzepatide, compared with treatment with mirikizumab and placebo, leads to decrease or disa...

Orlando, FLPHASE3350 participantsEli Lilly and Company

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NCT06398626Recruiting

An Observational Study of Etrasimod in Adult Patients With Moderate to Severe Ulcerative Colitis

The purpose of this observational study is to learn about the effects of etrasimod as a treatment for adult patients with moderate to severe ulcerative colitis. Patients will be treated according to s...

Orlando, FL300 participantsPfizer

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NCT06564974Recruiting

Registry Study to Observe Long-term Safety of Vamorolone (AGAMREE®) in Patients With Duchenne Muscular Dystrophy-SUMMIT

The goal of this study is to collect additional information on the safety of long-term treatment with AGAMREE® and to explore long-term clinical impact of AGAMREE® on quality of life, as assessed by s...

Orlando, FL250 participantsCatalyst Pharmaceuticals, Inc.

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NCT05547165Recruiting

Percutaneous Intervention Versus Observational Trial of Arterial Ductus in Low Weight Infants

Patent Ductus Arteriosus is a developmental condition commonly observed among preterm infants. It is a condition where the opening between the two major blood vessels leading from the heart fail to cl...

Orlando, FLNA240 participantsNationwide Children's Hospital

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NCT07296315Recruiting

Confirmatory Clinical Study in Active Ulcerative Colitis

The main goal of the study is to check if MH002 works and is safe to use. In a previous study in 45 patients with Ulcerative Colitis, MH002 was found to have favorable effects. In this study, 2 differ...

Orlando, FLPHASE2204 participantsMRM Health NV

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NCT07113522Recruiting

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

This is a Phase 2, multicenter, platform study in adult participants with IBD (moderately to severely active Crohn's Disease or Ulcerative Colitis). The primary goal of this study is to assess the saf...

Orlando, FLPHASE2140 participantsMirador Therapeutics, Inc.

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NCT05987852Recruiting

Hyperbaric Oxygen Therapy for Ulcerative Colitis (HBOT-UC)

Chronic intestinal hypoxia and accompanying mucosal inflammation is a hallmark of ulcerative colitis (UC). Hyperbaric oxygen therapy (HBOT) involves breathing 100% oxygen under increased atmospheric p...

Orlando, FLNA126 participantsNorthwestern University

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NCT05076175Recruiting

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining clinical remission. Ozanimod will be administered orally to pediatric participa...

Orlando, FLPHASE2120 participantsBristol-Myers Squibb

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NCT06696014Recruiting

Mirikizumab Real World Protocol

The goal of this observational study is to learn about how effective mirikizumab (Omvoh) is when treating patients with ulcerative colitis (UC) Does mirikizumab (Omvoh) lead to a reduction in symptom...

Orlando, FL100 participantsUniversity of North Carolina, Chapel Hill

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NCT05874414Recruiting

Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

This is an open-label, multicenter Phase 1b/2a study to evaluate safety, pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of GNS561 in combination with trametinib in Advanced KRAS Mutated Cho...

Orlando, FLPHASE198 participantsGenfit

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NCT06128018Recruiting

Comparing Endoscopic Ultrasound vs Surgical Gastrojejunostomy for Management of GOO.

The goal of this interventional study is to learn about the outcomes between two options for the management of malignant gastric outlet obstruction....

Orlando, FLNA70 participantsAdventHealth

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NCT06095128Recruiting

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis (UC). Another aim...

Orlando, FLPHASE465 participantsTakeda

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NCT05287126Recruiting

A Study to Evaluate Etrasimod Treatment in Adolescents With Ulcerative Colitis

The purpose of this study is to determine the safety, efficacy, and pharmacokinetics (PK) of etrasimod for the treatment of moderately to severely active ulcerative colitis in adolescents (≥ 12 years ...

Orlando, FLPHASE236 participantsPfizer

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About Ulcerative Colitis Clinical Trials in Orlando

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 14 ulcerative colitis clinical trials recruiting participants in Orlando, FL. These studies are seeking a combined 2,729 participants. Research is being sponsored by Eli Lilly and Company, Pfizer, Catalyst Pharmaceuticals, Inc. and 9 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in Orlando — FAQ

Are there ulcerative colitis clinical trials in Orlando?

Yes, there are 14 ulcerative colitis clinical trials currently recruiting in Orlando, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orlando?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you about next steps.

Are clinical trials in Orlando free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orlando studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 14 active trials in Orlando are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated July 19, 2026 from ClinicalTrials.gov