Orlando, FL9 Active Studies

Ulcerative Colitis Clinical Trials in Orlando, FL

Find 9 actively recruiting ulcerative colitis clinical trials in Orlando, FL. Connect with local research sites and explore new treatment options.

9
Active Trials
8
Sponsors
1,593
Enrolling

Recruiting Ulcerative Colitis Studies in Orlando

RecruitingOrlando, FLNCT06581328

A Study of Vedolizumab in Adults With Ulcerative Colitis or Crohn's Disease in the Community Setting

Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (inflammation), bleeding from the anus, and belly pain. The main aim of this stud...

400 participants
Takeda
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RecruitingOrlando, FLNCT06937086

Mirikizumab Administered at the Same Time as Tirzepatide in Adult Participants With Moderately to Severely Active Ulcerative Colitis and Obesity or Overweight: Phase 3b Study

The main purpose of this study is to show whether in these individuals, treatment with both mirikizumab and tirzepatide, compared with treatment with mirikizumab and placebo, leads to decrease or disa...

350 participants
Eli Lilly and Company
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RecruitingOrlando, FLNCT06588855

A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (Also Known as RO7790121) in Participants With Moderately to Severely Active Ulcerative Colitis

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with mo...

350 participants
Hoffmann-La Roche
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RecruitingOrlando, FLNCT06127043

A Study of Efficacy and Safety of Rosnilimab in Subjects with Moderate to Severe Ulcerative Colitis (ROSETTA)

ROSETTA STUDY: This study will evaluate the safety, tolerability, and efficacy of Rosnilimab in subjects with moderate to severe ulcerative colitis (UC)...

132 participants
AnaptysBio, Inc.
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RecruitingOrlando, FLNCT05076175

A Study Investigating Oral Ozanimod (RPC1063) in Pediatric Participants With Moderate to Severe Active Ulcerative Colitis

The purpose of this study is to evaluate the effectiveness and safety of ozanimod (RPC1063) in achieving and maintaining clinical remission. Ozanimod will be administered orally to pediatric participa...

120 participants
Bristol-Myers Squibb
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RecruitingOrlando, FLNCT07113522

A Phase 2 Study to Evaluate Therapies for Inflammatory Bowel Disease

This is a Phase 2, multicenter, platform study in adult participants with IBD (moderately to severely active Crohn's Disease or Ulcerative Colitis). The primary goal of this study is to assess the saf...

90 participants
Mirador Therapeutics, Inc.
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RecruitingOrlando, FLNCT06095128

A Study of Vedolizumab With Tofacitinib in Adults With Ulcerative Colitis (UC)

The main aim of this study is to learn about the effect of treatment with vedolizumab IV (vedolizumab) together with tofacitinib in adults with moderate and severe ulcerative colitis (UC). Another aim...

65 participants
Takeda
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RecruitingOrlando, FLNCT06109441

Efficacy/Safety of ALTB-268 in Subjects w/Moderately to Severely Active UC Refractory to Biologics

ALTB-268-201 is a Phase 2a, multicenter, single arm, multiple-dose, open-label study evaluating the efficacy and safety of ALTB-268 in subjects with moderately to severely active UC. The study consist...

50 participants
AltruBio Inc.
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RecruitingOrlando, FLNCT06315738

Study to Assess the Safety, Tolerability, and Preliminary Efficacy of ST266 in Infants With Necrotizing Enterocolitis

The primary objective of this study is to determine the safety and tolerability of two dose levels (0.5 mL/kg and 1.0 mL/kg) of once daily (QD) via IV route of administration of ST266 in treating pati...

36 participants
Noveome Biotherapeutics, formerly Stemnion
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About Ulcerative Colitis Clinical Trials in Orlando

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 9 ulcerative colitis clinical trials recruiting participants in Orlando, FL. These studies are seeking a combined 1,593 participants. Research is being sponsored by Takeda, Eli Lilly and Company, Hoffmann-La Roche and 5 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in Orlando — FAQ

Are there ulcerative colitis clinical trials in Orlando?

Yes, there are 9 ulcerative colitis clinical trials currently recruiting in Orlando, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Orlando?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Orlando research site will contact you about next steps.

Are clinical trials in Orlando free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Orlando studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 9 active trials in Orlando are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated March 2, 2026 from ClinicalTrials.gov