42 Essential Tremor Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting Essential Tremor Studies in Philadelphia

NCT07133074Recruiting

Allergy Delabeling in Antibiotic Stewardship - Intervention

The overall goal of the RENEW-IN intervention is to assess the impact of a BL allergy delabeling intervention on antibiotic use and clinical outcomes in patients with a hematologic malignancy....

Philadelphia, PAPHASE43,800 participantsAbramson Cancer Center at Penn Medicine

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NCT04098445Recruiting

TRANSPIRE: Lung Injury in a Longitudinal Cohort of Pediatric HSCT Patients

Hematopoietic stem cell transplant (HSCT) is an effective but toxic therapy and pulmonary morbidity affects as many as 25% of children receiving transplant. Early pulmonary injury includes diffuse alv...

Philadelphia, PA2,000 participantsChildren's Hospital Medical Center, Cincinnati

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NCT00288119Recruiting

Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

The overall objectives of this BETRNet Research Center (RC) are: 1. to conduct a rigorous, integrated spectrum of transdisciplinary human research in Barrett's esophagus (BE) and esophageal adenocarc...

Philadelphia, PA2,000 participantsCase Western Reserve University

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NCT06980025Recruiting

Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial

This is a phase-III multi-center double-blind randomized clinical trial of 1,800 individuals with a history of prior preterm birth at less than 35 weeks gestation who are randomized to either 162 mg a...

Philadelphia, PAPHASE31,800 participantsThe George Washington University Biostatistics Center

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NCT06377033Recruiting

Using the EHR to Advance Genomic Medicine Across a Diverse Health System

Given the expansion of indications for genetic testing and our understanding of conditions for which the results change medical management, it is imperative to consider novel ways to deliver care beyo...

Philadelphia, PANA1,000 participantsUniversity of Pennsylvania

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NCT04959097Recruiting

Retinoblastoma Patient Clinical Database and Tissue Repository

Retinoblastoma (RB) is a primary eye cancer that forms in the back of the eye of infants and toddlers. Traditionally, RB is diagnosed without a biopsy; tumor can only be studied once an eye has been s...

Philadelphia, PA800 participantsChildren's Hospital Los Angeles

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NCT04064060Recruiting

A Study to Evaluate Long-term Safety in Participants Who Have Participated in Other Luspatercept (ACE-536) Clinical Trials

A Phase 3b, open-label, single-arm, rollover study to evaluate the long-term safety of luspatercept, to the following participants: * Participants receiving luspatercept on a parent protocol at the t...

Philadelphia, PAPHASE3665 participantsCelgene

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NCT06628453Recruiting

CGM for Management of Type 2 Diabetes in Pregnancy

The goal of this clinical trial is to learn if continuous glucose monitoring works better than self-monitoring of blood glucose (fingersticks) to treat type 2 diabetes in pregnancy. It will also learn...

Philadelphia, PANA564 participantsUniversity of Alabama at Birmingham

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NCT06419777Recruiting

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes

The aim of our study is to compare neonatal and maternal outcomes using different thresholds for the initiation and titration of pharmacotherapy for gestational diabetes (GDM). Our goal is to compare ...

Philadelphia, PANA430 participantsThomas Jefferson University

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NCT06419803Recruiting

Strict Versus Permissive Thresholds for Initiation of Pharmacotherapy in Gestational Diabetes (START 2)

Philadelphia, PANA430 participantsThomas Jefferson University

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NCT05215353Recruiting

A Study Comparing Music Therapy and Cognitive Behavioral Therapy for Anxiety in Cancer Survivors

The researchers are doing this study to compare how music therapy and cognitive behavioral therapy, given virtually, may be able to reduce anxiety in people who have had cancer. In addition, this stud...

Philadelphia, PAPHASE4368 participantsMemorial Sloan Kettering Cancer Center

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NCT05818683Recruiting

A Study of Pasritamig (JNJ-78278343) in Combination With Other Agents for Metastatic Prostate Cancer

The purpose of this study is to identify the recommended phase 2 regimen(s) RP2R(s) of pasritamig and combination regimens in Part 1 (dose escalation) and to determine safety at the putative RP2R(s) o...

Philadelphia, PAPHASE1300 participantsJanssen Research & Development, LLC

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NCT07205718Recruiting

A Study of TAK-188 in Adults With Advanced or Spreading Solid Tumors

TAK-188 is a new medicine that targets a protein called CCR8, which is found on the surface of certain cells (Tregs) inside tumors. These cells can weaken the body's ability to fight cancer. TAK-188 m...

Philadelphia, PAPHASE1223 participantsTakeda

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NCT07167004Recruiting

The GRoceries Aimed at Increasing Nutrition Study

Only 2% of Americans meet the recommended levels of whole grain consumption, despite its association with reduced risk of type 2 diabetes. This study aims to assess if consumers with prediabetes or ty...

Philadelphia, PANA216 participantsUniversity of Pennsylvania

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NCT05932589Recruiting

Neurophysiologic Biomarkers in Rett Syndrome

The goal of this observational study is to identify candidate biomarkers in individuals with Rett Syndrome (RTT). The main questions it aims to answer are: * Do these biomarkers change during clinica...

Philadelphia, PA202 participantsChildren's Hospital of Philadelphia

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NCT07444203Recruiting

Transformative Research in Diabetic Nephropathy 2.0

The goal of this observational study is to learn more about kidney health in adults with diabetic kidney disease and other groups. Researchers will study kidney tissue and other samples. They want to ...

Philadelphia, PA200 participantsUniversity of Pennsylvania

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NCT05422911Recruiting

Abiraterone, Enzalutamide, or Apalutamide in Castrate-sensitive Prostate Cancer.

The investigators have used national VHA data to demonstrate real-world efficacy of abiraterone and enzalutamide in Veterans with mCRPC. In the real-world that is the VHA, the investigators have succe...

Philadelphia, PAPHASE2192 participantsSun Pharmaceutical Industries Limited

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NCT06271512Recruiting

A Study of Participants with Β-Thalassemia Treated with Betibeglogene Autotemcel

The main aim of this study is to collect real-world longitudinal data on participants with β-thalassemia treated with betibeglogene autotemcel (beti-cel) in the post marketing setting. To assess the l...

Philadelphia, PA150 participantsGenetix Biotherapeutics Inc.

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NCT06055439Recruiting

A Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 Chimeric Antigen Receptor (CAR) T Cell Therapy

The goal of this clinical trial is to evaluate CHM-2101, an autologous CDH17 CAR T-cell therapy for the treatment of advanced gastrointestinal (GI) cancers that are relapsed or refractory to at least ...

Philadelphia, PAPHASE1135 participantsChimeric Therapeutics

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NCT07014176Recruiting

Nonhealing Diabetic Foot Ulcers Treated With Standard of Care (SOC) Alone or Standard of Care and Amnion-Intermediate-Chorion (AIC)

The purpose of this study is to determine how well our dHPT (Dehydrated Human Placental Tissue) Product and Standard of Care work when compared to Standard of Care alone in achieving complete closure ...

Philadelphia, PAPHASE4120 participantsCellution Biologics

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NCT05487846Recruiting

Peer Navigation for the Support of Metastatic Prostate Cancer Patients Undergoing Genetic Evaluation

This clinical trial evaluates whether having a trained peer navigator helps African American men with prostate cancer that has spread to other parts of the body (metastatic) understand and navigate th...

Philadelphia, PANA120 participantsThomas Jefferson University

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NCT06852365Recruiting

Combined Oral Contraceptive Pill and Resistance Starch

This study will enroll women with PCOS to study the effects of first line therapy, oral contraceptive pills, and then either 12 weeks of resistant starch or 12 weeks of placebo to explore if resistant...

Philadelphia, PAPHASE2100 participantsUniversity of Pennsylvania

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NCT05878860Recruiting

ATSN-201 Gene Therapy in RS1-Associated X-linked Retinoschisis

This study will evaluate the safety and tolerability of ATSN-201 in male subjects ≥ 6 years of age with RS1-associated X-linked retinoschisis (XLRS)....

Philadelphia, PAPHASE397 participantsAtsena Therapeutics Inc.

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NCT05932680Recruiting

Limited-duration Teclistamab

This is a single-arm, non-inferiority study in which patients who have achieved a very good partial response (VGPR) or better, according to International Myeloma Working Group (IMWG) response criteria...

Philadelphia, PAPHASE275 participantsAbramson Cancer Center at Penn Medicine

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NCT07108114Recruiting

SLV-324 Treatment of Metastatic Solid Tumors

This is a Phase 1 dose-escalation study evaluating the safety, pharmacokinetics, pharmacodynamics, immunogenicity, and efficacy of SLV-324 across a range of dose levels when administered to subjects w...

Philadelphia, PAPHASE170 participantsSolve Therapeutics

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NCT07140900Recruiting

Study Evaluating the Safety, Tolerability, and Efficacy of Xaluritamig in Combination With Androgen Receptor Pathway Inhibitors in Participants With Metastatic Hormone-sensitive Prostate Cancer

The main objective of the trial is to evaluate the safety and tolerability of xaluritamig in combination with darolutamide or abiraterone....

Philadelphia, PAPHASE160 participantsAmgen

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NCT06815237Recruiting

Effects of Ketone Supplement and Alcohol on Brain Metabolism

The research study is being conducted to better understand the effects of ketones and alcohol on brain functioning and brain metabolism. Participants will be asked to undergo three identical MRI visit...

Philadelphia, PAPHASE260 participantsUniversity of Pennsylvania

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NCT06789445Recruiting

A Study to Investigate the Safety of OpCT-001 in Adults Who Have Primary Photoreceptor Disease (CLARICO)

Study OpCT-001-101 is a Phase 1/2a first-in-human, multisite, 2-part interventional study to evaluate the safety, tolerability, and the effect on clinical outcomes of OpCT-001 in up to approximately 5...

Philadelphia, PAPHASE154 participantsBlueRock Therapeutics

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NCT03646617Recruiting

Ipilumumab and Nivolumab With or Without Hypofractionated Radiotherapy in Patients With Metastatic Melanoma

The main purpose of this study is to determine the safety of combining ipilimumab and nivolumab with hypofractionated radiotherapy to a single tumor in patients with metastatic melanoma. Another purpo...

Philadelphia, PAPHASE254 participantsAbramson Cancer Center at Penn Medicine

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NCT04786262Recruiting

A Safety, Tolerability, and Efficacy Study of VX-880 in Participants With Type 1 Diabetes

This study will evaluate the safety, tolerability and efficacy of VX-880 infusion in participants with Type 1 diabetes (T1D) and impaired awareness of hypoglycemia (IAH) and severe hypoglycemia....

Philadelphia, PAPHASE352 participantsVertex Pharmaceuticals Incorporated

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NCT07567131Recruiting

Observational Study of Adults and Adolescents With Erythropoietic Protoporphyria (EPP) and X-linked Porphyria (XLP)

The purpose of this study is to collect information about the effects of EPP/XLP in adults and adolescents. This is an observational study in which participants will not receive any treatment. Study d...

Philadelphia, PA50 participantsPortal Therapeutics, Inc.

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NCT07493512Recruiting

Trial of Xaluritamig in Adults With Metastatic Castration-resistant Prostate Cancer

The primary objective of this trial is to determine the safety profile of xaluritamig at the proposed regimen in adult participants with metastatic castration-resistant prostate cancer (mCRPC)....

Philadelphia, PAPHASE140 participantsAmgen

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NCT05705024Recruiting

Efficacy of Locally Delivered Allogeneic Mesenchymal Stromal Cells

The proposed Conventional Cohort Expansion Study involves the use of Mesenchymal Stromal Cells (MSCs) are derived from the bone marrow. We previously studied the safety of subconjunctival injection of...

Philadelphia, PAPHASE238 participantsUniversity of Illinois at Chicago

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NCT06880835Recruiting

Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery

This investigator-initiated study will enroll about 30 adults 18 to 65 years of age with type 1 diabetes (T1D) who are using the Tandem t:slim X2 insulin pump or Tandem Mobi insulin pump with Control-...

Philadelphia, PANA30 participantsJaeb Center for Health Research

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NCT06587165Recruiting

Quantifying New Heart Muscle Cells

Regenerative therapies could provide new ways of treating heart failure. Unlike many organs in the human body, such as the skin and the GI tract, the ability to regenerate heart muscle decreases after...

Philadelphia, PANA30 participantsWeill Medical College of Cornell University

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NCT06535789Recruiting

Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes

Pregnant women aged 18-40 with gestational diabetes (GDM) will take part in this study. We want to see how two different insulin treatments affect their blood sugar after they eat. These women usually...

Philadelphia, PAPHASE230 participantsJaeb Center for Health Research

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NCT06643884Recruiting

Suprachoroidal Administration in Subjects With Choroidal Metastasis From Breast or Lung Primary Tumors

The primary objective is to assess the safety and tolerability of bel-sar treatment in subjects with choroidal metastasis from breast or lung primary tumors....

Philadelphia, PAPHASE224 participantsAura Biosciences

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NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

Philadelphia, PAPHASE120 participantsAdaptimmune

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NCT06364774Recruiting

ALS20-101 Lentiviral Gene Therapy for Beta Thalassemia

The main goal of this study is to find out if the blood disorder called transfusion-dependent beta thalassemia can be safely treated by modifying blood stem cells. This is done by collecting blood ste...

Philadelphia, PAPHASE112 participantsChildren's Hospital of Philadelphia

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NCT07282847Recruiting

A Study to Evaluate Safety, Tolerability, and Efficacy of AB-1009 Gene Therapy (GAA Gene) in Adult Participants With Late Onset Pompe Disease (PROGRESS-GT LOPD)

This is a single-arm, open-label, dose-escalation study to evaluate the safety, tolerability and efficacy of a single intravenous infusion of AB-1009 in adult participants with late-onset Pompe diseas...

Philadelphia, PAPHASE112 participantsAskBio Inc

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NCT07114939Recruiting

FTT PET/CT in Pancreatic Neuroendocrine Tumors

A pilot study to evaluate the expression of PARP-1 in patients with pancreatic neuroendocrine tumors will be conducted. This will be done via the use of a novel PET imaging agent, \[18F\]FluorThanatra...

Philadelphia, PAPHASE112 participantsAbramson Cancer Center at Penn Medicine

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NCT06832410Recruiting

An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant

This study will evaluate the efficacy, safety, and tolerability of VX-880 in participants with Type 1 Diabetes (TID) with a kidney transplant....

Philadelphia, PAPHASE310 participantsVertex Pharmaceuticals Incorporated

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About Essential Tremor Clinical Trials in Philadelphia

Essential tremor is one of the most common movement disorders, causing involuntary shaking, most often in the hands. It is different from Parkinson's disease, though the two can be confused. Treatment includes medications, focused ultrasound, and deep brain stimulation for severe cases.

There are currently 42 essential tremor clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 16,645 participants. Research is being sponsored by Abramson Cancer Center at Penn Medicine, Children's Hospital Medical Center, Cincinnati, Case Western Reserve University and 26 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Essential Tremor Clinical Trials in Philadelphia — FAQ

Are there essential tremor clinical trials in Philadelphia?

Yes, there are 42 essential tremor clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What essential tremor treatments are being tested?

The 42 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for essential tremor.

Data updated July 16, 2026 from ClinicalTrials.gov