15 Parkinsons Disease Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting Parkinsons Disease Studies in Philadelphia

NCT06933758Recruiting

Temple Health Chest Initiative (THCI 2.0)

Chronic obstructive pulmonary disease is highly prevalent globally, with considerable morbidity and mortality associated. In the US, it is the 4th leading cause of death, as well as contributing to si...

Philadelphia, PA1,000 participantsTemple University

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NCT06600126Recruiting

Supporting Evidence-based Responses to Emotional Needs in Emphysema

The goal of this clinical trial is to understand how a Coping Skills Training program can reduce depression and anxiety in people with chronic obstructive pulmonary disease (COPD), particularly those ...

Philadelphia, PANA750 participantsUniversity of Pennsylvania

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NCT07684820Recruiting

To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment

This is a Phase 2 study of the efficacy, safety, tolerability and pharmacokinetics of two doses of EXPD-101 in participants with COPD. Study participants will be randomized to receive either study dru...

Philadelphia, PAPHASE2600 participantsExpedition Therapeutics, Inc

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NCT07118306Recruiting

COPD Exacerbation Follow Up

The goal of this study is to evaluate the impact of implementing an AI-enabled clinical workflow tool (Viz COPD) on respiratory specialist follow up and clinical outcomes after an acute exacerbation....

Philadelphia, PA485 participantsViz.ai, Inc.

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NCT06974981Recruiting

Leveraging Lung Cancer Screening to Optimize Screening Outcomes and COPD Management: COPD in LCS Registry

The COPD in LCS Registry will identify and characterize individuals who have functional or radiographic evidence of COPD and are receiving lung cancer screening. Clinical information will be obtained ...

Philadelphia, PA420 participantsSidney Kimmel Comprehensive Cancer Center at Thomas Jefferson University

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NCT04997642Recruiting

Parkinson's Disease and Movement Disorders Clinical Database

The research database contains demographic and family history information, longitudinal information on the clinical symptoms, neuropsychological profile and treatments, stored biological samples, and ...

Philadelphia, PA250 participantsUniversity of Pennsylvania

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NCT07051707Recruiting

Evaluating the Safety and Efficacy of dNerva Lung Denervation System in Patients With COPD

The dNerva Lung Denervation System is one-time treatment intended to improve breathing in Chronic Obstructive Pulmonary Disease (COPD) patients on standard medical care. The purpose of this study is t...

Philadelphia, PANA200 participantsNuvaira, Inc.

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NCT06848530Recruiting

Neurophysiology of the Basal Ganglia, Thalamus, and Cerebellum in Patients With Movement Disorders

The research study is being conducted to better understand parts of the human brain called the cortex, basal ganglia, thalamus, and cerebellum in patients with movement disorders (such as Parkinson's ...

Philadelphia, PANA100 participantsUniversity of Pennsylvania

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NCT07265596Recruiting

Early Longitudinal Imaging in the Parkinson's Progressive Marker Initiative (PPMI) Using (18F)AV-133 (PPMI AV-133 Prodromal Imaging)

The study is a longitudinal, multi-center study to assess progression of \[18F\] AV-133 imaging in Prodromal PD participants. Participants will be followed for up to 24 months. Approximately 100 Prodr...

Philadelphia, PAPHASE2100 participantsMichael J. Fox Foundation for Parkinson's Research

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NCT07222410Recruiting

Closed Loop Oxygen Control in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Nasal High Flow in the Hospital

The trial aims to evaluate whether the Airvo 3 device in OptiO2 mode can maintain patients' SpO2 levels within the target range better than manual oxygen titration in hospitalized COPD patients with h...

Philadelphia, PANA70 participantsFisher and Paykel Healthcare

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NCT05539196Recruiting

A Post-Approval Registry for Exablate 4000 Type 1.0 and Type 1.1 for Unilateral Pallidotomy for the Treatment of Advanced, Idiopathic Parkinson's Disease With Medication-refractory Moderate to Severe Motor Complications

This registry is a prospective, multicenter, international, single arm, observational post-approval registry with follow-up at 3, 6, and 12 months, and annually for 5 years. The proposed registry will...

Philadelphia, PA60 participantsInSightec

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NCT07450859Recruiting

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

This is a Phase 2 study for nuzefatide pevedotin (BT5528) in adults with a specific type of pancreatic cancer called metastatic pancreatic ductal adenocarcinoma (PDAC) that has spread and worsened aft...

Philadelphia, PAPHASE239 participantsBicycleTx Limited

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NCT05070013Recruiting

Adaptive Neurostimulation to Restore Sleep in Parkinson's Disease (Aim 2)

Parkinson's Disease (PD) is the second most common of the age-related neurodegenerative disorders, affecting over 1,900 adults per 100,000 over the age of 80 in the US. The prevalence of sleep dysfunc...

Philadelphia, PANA20 participantsUniversity of Nebraska

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NCT07554560Recruiting

Nutrition Intervention for Pancreatic Cancer

Patients with pancreatic cancer (pancreatic ductal adenocarcinoma (PDAC) and pancreatic neuroendocrine tumor (NET)) commonly experience fat malabsorption due to exocrine pancreatic insufficiency (EPI)...

Philadelphia, PANA18 participantsChildren's Hospital of Philadelphia

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NCT06984562Recruiting

Adaptive Radiation for Locally Advanced Unresectable Pancreatic Cancer

The goal of this clinical trial is to learn if Adaptive Radiation Therapy (ART) is safe and effective in treating patients with locally advanced pancreatic cancer. The main questions the study aims t...

Philadelphia, PANA16 participantsFox Chase Cancer Center

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About Parkinsons Disease Clinical Trials in Philadelphia

Parkinson's disease is a progressive nervous system disorder that affects movement, causing tremors, stiffness, and difficulty with balance. It results from the loss of dopamine-producing neurons in the brain. Treatment includes medications, deep brain stimulation, and emerging therapies targeting disease modification.

There are currently 15 parkinsons disease clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 4,128 participants. Research is being sponsored by Temple University, University of Pennsylvania, Expedition Therapeutics, Inc and 10 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Parkinsons Disease Clinical Trials in Philadelphia — FAQ

Are there parkinsons disease clinical trials in Philadelphia?

Yes, there are 15 parkinsons disease clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What parkinsons disease treatments are being tested?

The 15 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for parkinsons disease.

Data updated July 17, 2026 from ClinicalTrials.gov