5 Traumatic Brain Injury Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting Traumatic Brain Injury Studies in Philadelphia

NCT07455136Recruiting

A Study to Develop a Blood-based Test for Aiding the Diagnosis/Prognosis of Traumatic Brain Injury in Adults and for Monitoring the Development of Secondary Events in Patients Diagnosed With Traumatic Brain Injury

The study is intended to cover two purposes: first, to develop a blood-based biomarker test for aiding the diagnosis of traumatic brain injury (TBI) in adult participants and for prognosis of outcome ...

Philadelphia, PA2,000 participantsHoffmann-La Roche

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NCT05741411Recruiting

Facilitating Access to Specialty Treatment

The goal of this hybrid implementation-effectiveness study is to evaluate the effectiveness (hastened recovery times) and feasibility (fidelity in connecting to concussion specialty care) of a novel m...

Philadelphia, PANA210 participantsChildren's Hospital of Philadelphia

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NCT05782244Recruiting

Sildenafil for Microvasculopathy in Chronic TBI

Traumatic Cerebral Vascular Injury (TCVI) is a common consequence of traumatic brain injury (TBI), including mild TBI (mTBI). TCVI is associated with poor recovery after TBI in animal models. TCVI can...

Philadelphia, PAPHASE2160 participantsUniversity of Pennsylvania

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NCT07282691Recruiting

Validation of Clinical Outcome Measures Specific to mTBI-Related Oculomotor Disorders

The specific aim of this project is to validate clinical tests to be used as outcome measures in studies of mTBI-related vision problems....

Philadelphia, PA150 participantsSalus University

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NCT05725993Recruiting

Longitudinal Assessment of Traumatic Microvascular Injury-2

The goal of this observational study is to learn about changes in the brain of patients over the first 3 years following a traumatic brain injury (TBI). The main question it aims to answer are: \- Ho...

Philadelphia, PA110 participantsUniversity of Pennsylvania

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About Traumatic Brain Injury Clinical Trials in Philadelphia

Traumatic brain injury (TBI) results from a violent blow or jolt to the head or body that disrupts normal brain function. Effects can range from mild concussions to severe cognitive impairment. Treatment depends on severity and may include rehabilitation, medication, and surgery.

There are currently 5 traumatic brain injury clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 2,630 participants. Research is being sponsored by Hoffmann-La Roche, Children's Hospital of Philadelphia, University of Pennsylvania and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Traumatic Brain Injury Clinical Trials in Philadelphia — FAQ

Are there traumatic brain injury clinical trials in Philadelphia?

Yes, there are 5 traumatic brain injury clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What traumatic brain injury treatments are being tested?

The 5 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for traumatic brain injury.

Data updated July 17, 2026 from ClinicalTrials.gov