4 Insomnia Clinical Trials in Philadelphia, PA (2026)

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Recruiting Insomnia Studies in Philadelphia

NCT07542756Recruiting

A SMART Approach to Evaluating the Benefits of Common Prescription and OTC Medications for Insomnia

The purpose of this study is to assess the relative effectiveness, safety, and durability of the most commonly used prescription (zolpidem, trazodone) and over-the-counter (OTC) (melatonin, diphenhydr...

Philadelphia, PA1,200 participantsUniversity of Pennsylvania

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NCT06655883Recruiting

A Study of Suvorexant (MK-4305) for the Treatment of Insomnia Disorder in Participants With Opioid Use Disorder (MK-4305-098)

People with opioid use disorder (OUD) can have trouble falling or staying asleep. Researchers want to know if suvorexant will help people with OUD fall asleep and stay asleep. The goal of this study i...

Philadelphia, PA300 participantsMerck Sharp & Dohme LLC

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NCT06963463Recruiting

Transdiagnostic Sleep and Circadian Intervention + Bright Light in Adolescents With Elevated Depression (TranS-C+BL)

The goal of this clinical trial is to adapt a sleep intervention for individuals representative of all demographic groups, including those who are at the highest risk for suicidal behavior. Sleep diff...

Philadelphia, PA90 participantsUniversity of Pittsburgh

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NCT05301543Recruiting

Insomnia Behavioral Intervention Study

This randomized pilot study (n=20) explores the effects of a behavioral intervention, that includes sleep hygiene improvements, in long-term users of sleeping pills, aiming to alleviate or stabilize s...

Philadelphia, PA20 participantsUniversity of Pennsylvania

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About Insomnia Clinical Trials in Philadelphia

Insomnia is a common sleep disorder characterized by difficulty falling asleep, staying asleep, or getting restful sleep. Chronic insomnia affects about 10% of adults and can impair daytime functioning. Treatment includes cognitive behavioral therapy for insomnia (CBT-I) and medications.

There are currently 4 insomnia clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 1,610 participants. Research is being sponsored by University of Pennsylvania, Merck Sharp & Dohme LLC, University of Pittsburgh. Clinical trial participation is free and participants receive study-related medical care at no cost.

Insomnia Clinical Trials in Philadelphia — FAQ

Are there insomnia clinical trials in Philadelphia?

Yes, there are 4 insomnia clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What insomnia treatments are being tested?

The 4 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for insomnia.

Data updated July 13, 2026 from ClinicalTrials.gov