45 Ulcerative Colitis Clinical Trials in Philadelphia, PA (2026)

Q: Are there ulcerative colitis clinical trials in Philadelphia?

Yes, there are 45 ulcerative colitis clinical trials currently recruiting in Philadelphia, PA.

Q: How do I join a clinical trial in Philadelphia?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you.

Q: Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Ulcerative Colitis Studies in Philadelphia

NCT00286637Recruiting

Novel Glaucoma Diagnostics

The purpose of this research is to evaluate novel technologies for the assessment of ocular structure and function, including the scanning device called Optical Coherence Tomography (OCT). We will tes...

Philadelphia, PA5,000 participantsWills Eye

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NCT05759988Recruiting

Cervical Ripening as an Outpatient Method Using the Foley (COMFORT)

A multicenter pragmatic randomized trial of nulliparous women undergoing a term (≥37 weeks) induction of labor wherein the provider intends to use a Foley catheter for cervical ripening. The investiga...

Philadelphia, PANA2,300 participantsUniversity of Pennsylvania

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NCT03487185Recruiting

Continuous Positive Airway Pressure (CPAP) for Sleep Apnea in Pregnancy

A randomized controlled trial of 1,500 women to assess whether treatment of obstructive sleep apnea with continuous positive airway pressure (CPAP) in pregnancy will result in a reduction in the rate ...

Philadelphia, PANA1,500 participantsThe George Washington University Biostatistics Center

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NCT06413927Recruiting

Driver Education Research Study

This study will test the effectiveness of different types of driver training interventions for reducing young new driver crash risk early after licensure....

Philadelphia, PANA1,300 participantsChildren's Hospital of Philadelphia

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NCT06302439Recruiting

PROPEL - A Prospective Observational Patient Registry to Evaluate ENPP1 and ABCC6 Deficiency

The purpose of this prospective registry is to characterize the natural history of ectonucleotide pyrophosphatase/phosphodiesterase1(ENPP1) Deficiency and the infantile-onset form of adenosine triphos...

Philadelphia, PA1,000 participantsInozyme Pharma

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NCT06933758Recruiting

Temple Health Chest Initiative (THCI 2.0)

Chronic obstructive pulmonary disease is highly prevalent globally, with considerable morbidity and mortality associated. In the US, it is the 4th leading cause of death, as well as contributing to si...

Philadelphia, PA1,000 participantsTemple University

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NCT07209254Recruiting

Randomized Controlled Trial of Two Mobile Health Strategies to Manage Postpartum Hypertension

A multicenter randomized trial that will compare the effectiveness of two postpartum blood pressure (BP) management strategies in improving blood pressure and cardiac function and increasing patient e...

Philadelphia, PANA770 participantsJennifer Lewey, MD, MPH

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NCT07684820Recruiting

To Evaluate the Effect of EXPD-101/FXS7553 Compared With Placebo in Patients With COPD Over 52 Weeks of Treatment

This is a Phase 2 study of the efficacy, safety, tolerability and pharmacokinetics of two doses of EXPD-101 in participants with COPD. Study participants will be randomized to receive either study dru...

Philadelphia, PAPHASE2600 participantsExpedition Therapeutics, Inc

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NCT01484678Recruiting

Magnetic Resonance Imaging and Biomarkers for Muscular Dystrophy

The purpose of this research study is to determine the potential of magnetic resonance imaging, spectroscopy, and whole body imaging to monitor disease progression and to serve as an objective outcome...

Philadelphia, PA550 participantsUniversity of Florida

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NCT06189755Recruiting

MicroRNAs as Biomarkers for Obstructive Sleep Apnea

Although obstructive sleep apnea (OSA) is a common disorder, there are no blood biomarkers for identification and management of these patients. This project will study microRNAs in order to develop an...

Philadelphia, PA500 participantsUniversity of Pennsylvania

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NCT07118306Recruiting

COPD Exacerbation Follow Up

The goal of this study is to evaluate the impact of implementing an AI-enabled clinical workflow tool (Viz COPD) on respiratory specialist follow up and clinical outcomes after an acute exacerbation....

Philadelphia, PA485 participantsViz.ai, Inc.

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NCT06456554Recruiting

Acellular Dermal Matrix Investigation in Breast Reconstruction

Prospective, multi-center, dual-arm non-randomized clinical study in females undergoing a two-stage breast reconstruction using a pre-pectoral technique....

Philadelphia, PANA467 participantsRTI Surgical

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NCT00360646Recruiting

Drug-Induced Liver Injury (DILI) Network Retrospective

The purpose of this study is to establish retrospectively a nationwide registry of patients who have suffered drug-induced liver injury (DILI), and to collect, immortalize, and store serum, DNA, and l...

Philadelphia, PA400 participantsDuke University

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NCT05382754Recruiting

Home Apnea Testing in CHildren Trial

This clinical trial will compare home sleep apnea testing with the gold standard in-lab polysomnography in terms of 1) accuracy, 2) therapeutic decision-making, and 3) parent/child acceptability in ch...

Philadelphia, PANA317 participantsChildren's Hospital of Philadelphia

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NCT06552637Recruiting

Synchronized Diaphragmatic Stimulation in Symptomatic Heart Failure

RECOVER HF is a clinical study designed to evaluate the safety and efficacy of Synchronized Diaphragmatic Stimulation delivered using the VisONE System in the treatment of patients with heart failure....

Philadelphia, PANA270 participantsVisCardia Inc.

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NCT05050383Recruiting

DISE: Phenotyping Obstruction Patterns

Drug-induced sleep endoscopy (DISE) represents an opportunity to evaluate the upper airway in sleep-like conditions. In its current clinical form, however, DISE does not routinely determine the functi...

Philadelphia, PANA241 participantsUniversity of Pennsylvania

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NCT06043440Recruiting

Down Syndrome Obstructive Sleep Apnea

The purpose of this study is to assess whether oxygen supplementation during sleep improves working memory and other clinical and patient-reported outcomes among children who have Down Syndrome (DS) w...

Philadelphia, PAPHASE2230 participantsBrigham and Women's Hospital

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NCT05742360Recruiting

Effect of CPAP on Blood Pressure in Excessively Sleepy Obstructive Sleep Apnea Subtype

The primary objective of this study is to determine the longer-term (6 months) effect of CPAP therapy on change in 24-hour mean blood pressure (24hMBP) in OSA subjects with the excessively sleepy symp...

Philadelphia, PA227 participantsOhio State University

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NCT03373968Recruiting

Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study

This is an open label, long-term safety, tolerability, and efficacy study of GIVINOSTAT in all DMD (Duchenne's muscular dystrophy) patients who have been previously treated in one of the GIVINOSTAT st...

Philadelphia, PAPHASE2206 participantsItalfarmaco

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NCT07280468Recruiting

Endotype DIrected Treatment for OSA in Down Syndrome

Down syndrome is the most common genetic cause of intellectual disability. People with Down syndrome often have obstructive sleep apnea (OSA), a condition where people have difficulties with breathing...

Philadelphia, PAPHASE4200 participantsUniversity of Arizona

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NCT07220876Recruiting

Safety and Effectiveness of the VisiPlate Aqueous Shunt in Patients With Refractory Open-Angle Glaucoma

A Prospective, Multicenter, Single-Arm, Open-Label Clinical Trial...

Philadelphia, PANA165 participantsAvisi Technologies Inc.

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NCT04844606Recruiting

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks ...

Philadelphia, PAPHASE3150 participantsEli Lilly and Company

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NCT02469662Recruiting

Clinical Outcomes Study of the Nexel Total Elbow

The objectives of the study are to confirm safety and performance of the Zimmer Nexel Total Elbow when used in primary or revision total elbow replacement....

Philadelphia, PANA134 participantsZimmer Biomet

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NCT07071519Recruiting

A Study to Learn More About How Risankizumab Works in Young Participants With Ulcerative Colitis

Ulcerative colitis (UC) is a type of inflammatory bowel disease that causes inflammation and bleeding from the lining of the rectum and colon (large intestine). This study will assess how Risankizumab...

Philadelphia, PAPHASE3120 participantsAbbVie

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NCT07199764Recruiting

Maintenance Combinatorial Myeloid Immunotherapy for Unresectable Pancreatic Cancer

Phase II, open-label, single-arm study of CD40/Dectin-1 immunotherapy as maintenance treatment in patients with unresectable pancreatic ductal adenocarcinoma (PDA) who have not progressed following 4-...

Philadelphia, PAPHASE2100 participantsUniversity of Pennsylvania

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NCT05874414Recruiting

Combination of GNS561 and Trametinib in Patients With Advanced KRAS Mutated Cholangiocarcinoma

This is an open-label, multicenter Phase 1b/2a study to evaluate safety, pharmacokinetics (PK), pharmacodynamics (PD) and efficacy of GNS561 in combination with trametinib in Advanced KRAS Mutated Cho...

Philadelphia, PAPHASE198 participantsGenfit

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NCT03675412Recruiting

Caffeine Consumption in Glaucoma Patients and Healthy Subjects

Caffeine is the most widely consumed drinking nutrient in the world. Caffeine effects various organs and the vascular system. It decreases ocular blood flow due to vasoconstriction....

Philadelphia, PANA80 participantsWills Eye

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NCT05275972Recruiting

Descemet Endothelial Thickness Comparison Trial II

Descemet Endothelial Thickness Comparison Trial (DETECT) II is a multi-center, outcome assessor-masked, placebo-controlled clinical trial randomizing 60 patients with Fuchs endothelial dystrophy to DM...

Philadelphia, PAPHASE360 participantsStanford University

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NCT06138639Recruiting

A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)

This is a multicenter, open-label, non-randomized study to investigate the safety, tolerability, and efficacy of a single intravenous (IV) infusion of SGT-003 in participants with Duchenne muscular dy...

Philadelphia, PAPHASE160 participantsSolid Biosciences Inc.

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NCT04457154Recruiting

Pediatric Post-Approval Registry

This registry is a prospective, multi-center, single-arm study of pediatric subjects (ages 18-21 years) who are undergoing implant of the Inspire Upper Airway Stimulation (UAS) System for the treatmen...

Philadelphia, PA60 participantsInspire Medical Systems, Inc.

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NCT06789770Recruiting

Nasal vs Oral Breathing in Drug Induced Sleep vs Natural Sleep

This project will provide important new information regarding (1) the relationship between route of breathing and airway collapsibility and (2) whether route of breathing during DISE (Drug-Induced Sle...

Philadelphia, PA50 participantsUniversity of Pennsylvania

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NCT07332013Recruiting

Urinary Titin Biomarker in DMD

A universal challenge in clinical investigation of novel therapeutics is the need for quantitative, objective biomarkers that directly address the mechanisms of disease and provide information relevan...

Philadelphia, PANA50 participantsChildren's Hospital of Philadelphia

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NCT06914557Recruiting

Scrambler Therapy With Duloxetine-based Usual Care vs Duloxetine-based Usual Care for Chemotherapy-induced Peripheral Neuropathy.

The investigators hypothesize that Scrambler therapy with duloxetine, compared to duloxetine-based usual care, will result in greater improvement in CIPN as measured by the BPI-Short Form. In addition...

Philadelphia, PAPHASE250 participantsFox Chase Cancer Center

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NCT07450859Recruiting

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

This is a Phase 2 study for nuzefatide pevedotin (BT5528) in adults with a specific type of pancreatic cancer called metastatic pancreatic ductal adenocarcinoma (PDAC) that has spread and worsened aft...

Philadelphia, PAPHASE239 participantsBicycleTx Limited

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NCT07431606Recruiting

Duloxetine in Inflammatory Bowel Diseases

This open-label, prospective, single-arm pilot study investigates the use of duloxetine, a central neuromodulator, for improving psychological distress and functional impairment in adults with inflamm...

Philadelphia, PAPHASE232 participantsUniversity of Pennsylvania

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NCT07167446Recruiting

Neuroprotective Potential of Cannabidiol (CBD) in Preventing Oxaliplatin (Ox)-Induced Neuropathy

This is a pilot, prospective, randomized study evaluating the feasibility and acceptability of incorporating hemp-derived cannabidiol (CBD) supplementation to prevent oxaliplatin-induced peripheral ne...

Philadelphia, PAEARLY_PHASE130 participantsFox Chase Cancer Center

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NCT06433050Recruiting

Sodium Glucose Co-transporter (SGLT) Inhibitors in Nonobstructive Hypertrophic Cardiomyopathy

The goal of this clinical trial is to learn if sotagliflozin, a dual SGLT1 and SGLT2 inhibitor, works to treat symptomatic, nonobstructive hypertrophic cardiomyopathy (noHCM) in adult patients. It wil...

Philadelphia, PAEARLY_PHASE126 participantsUniversity of Pennsylvania

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NCT06008626Recruiting

Clinical Trial of the Cryosa System for the Treatment of Obstructive Sleep Apnea

This is a prospective, multicenter, non-randomized single-arm safety and performance study to collect data to evaluate the safety of the Cryosa procedure to treat obstructive sleep apnea (OSA) in pati...

Philadelphia, PANA25 participantsCryosa, Inc.

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NCT07645573Recruiting

18F-FTHA IMAGING OF THE INTESTINAL AND CENTRAL LYMPHATIC SYSTEM

The project will be performed over a period of approximately two years. In the first year the \[18F\]FTHA tracer will be developed, optimized, and tested on normal volunteers. During the second year, ...

Philadelphia, PAEARLY_PHASE125 participantsUniversity of Pennsylvania

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NCT05996003Recruiting

NS-089/NCNP-02-201 in Boys With Duchenne Muscular Dystrophy (DMD)

This is a Phase 2, open-label, multi-center, 2-part study of NS-089/NCNP-02 administered by weekly IV infusion to ambulant boys aged ≥4 to \<15 years with DMD due to mutations amenable to exon 44 skip...

Philadelphia, PAPHASE220 participantsNS Pharma, Inc.

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NCT07228221Recruiting

Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma

The Investigators will investigate the efficacy of combining the standalone iStent infinite and iDose that are minimally invasive surgical and drug depot options are a safe and effective alternative t...

Philadelphia, PAPHASE420 participantsJonathon Myers

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NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

Philadelphia, PAPHASE120 participantsAdaptimmune

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NCT07554560Recruiting

Nutrition Intervention for Pancreatic Cancer

Patients with pancreatic cancer (pancreatic ductal adenocarcinoma (PDAC) and pancreatic neuroendocrine tumor (NET)) commonly experience fat malabsorption due to exocrine pancreatic insufficiency (EPI)...

Philadelphia, PANA18 participantsChildren's Hospital of Philadelphia

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NCT06984562Recruiting

Adaptive Radiation for Locally Advanced Unresectable Pancreatic Cancer

The goal of this clinical trial is to learn if Adaptive Radiation Therapy (ART) is safe and effective in treating patients with locally advanced pancreatic cancer. The main questions the study aims t...

Philadelphia, PANA16 participantsFox Chase Cancer Center

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NCT05734196Recruiting

The ENERGY Study: Evaluation of Safety and Tolerability of INZ-701 in Infants With ENPP1 Deficiency or ABCC6 Deficiency

The primary purpose of Study INZ701-104 (the ENERGY study) is to assess the safety and tolerability of INZ-701 in infants with ENPP1 Deficiency or with ABCC6 Deficiency....

Philadelphia, PAPHASE116 participantsInozyme Pharma

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About Ulcerative Colitis Clinical Trials in Philadelphia

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 45 ulcerative colitis clinical trials recruiting participants in Philadelphia, PA. These studies are seeking a combined 19,027 participants. Research is being sponsored by Wills Eye, University of Pennsylvania, The George Washington University Biostatistics Center and 28 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in Philadelphia — FAQ

Are there ulcerative colitis clinical trials in Philadelphia?

Yes, there are 45 ulcerative colitis clinical trials currently recruiting in Philadelphia, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Philadelphia?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Philadelphia research site will contact you about next steps.

Are clinical trials in Philadelphia free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Philadelphia studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 45 active trials in Philadelphia are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated July 16, 2026 from ClinicalTrials.gov