Phoenix, AZ7 Active Studies

Depression Clinical Trials in Phoenix, AZ

Find 7 actively recruiting depression clinical trials in Phoenix, AZ. Connect with local research sites and explore new treatment options.

7
Active Trials
6
Sponsors
2,545
Enrolling

Recruiting Depression Studies in Phoenix

RecruitingPhoenix, AZNCT06029439

Study to Assess the Safety and Effectiveness of NMRA-335140-501

This is a 52-week open-label extension (OLE) study that will evaluate the safety, tolerability, and effectiveness of NMRA-335140 in participants with major depressive disorder (MDD). Participants who ...

1,000 participants
Neumora Therapeutics, Inc.
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RecruitingPhoenix, AZNCT06775379

A Randomized Study of Azetukalner Versus Placebo in Major Depressive Disorder

X-NOVA2 is a Phase 3, multicenter, randomized, double-blind, placebo-controlled study to evaluate the clinical efficacy, safety, and tolerability of azetukalner as a monotherapy in adult participants ...

450 participants
Xenon Pharmaceuticals Inc.
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RecruitingPhoenix, AZNCT05922878

Study of ALTO-300 in MDD

The purpose of this study is to determine efficacy differences between ALTO-300 and placebo, used adjunctively to an antidepressant, related to patient characteristics....

321 participants
Alto Neuroscience
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RecruitingPhoenix, AZNCT06633016

Study of ABX-002 for the Adjunctive Treatment of Major Depressive Disorder (AMPLIFY)

The goal of this clinical trial is to learn if ABX-002 added to an existing antidepressant treatment will benefit depression symptoms in adults with moderate to severe major depressive disorder who ha...

230 participants
Autobahn Therapeutics, Inc.
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RecruitingPhoenix, AZNCT06564818

"A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder"

The purpose of this study is to examine the efficacy, safety, and tolerability of CYB003 compared to matching placebo as adjunctive treatment in participants with MDD....

220 participants
Cybin IRL Limited
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RecruitingPhoenix, AZNCT06656416

ALTO-100 in Bipolar Disorder With Depression (BD-D)

The purpose of this study is to assess antidepressant efficacy differences between ALTO-100 and placebo during the Double-Blind period in patients with bipolar disorder I or II with current major depr...

200 participants
Alto Neuroscience
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RecruitingPhoenix, AZNCT06785012

A Study to Explore the Efficacy of JNJ-89495120 in the Treatment of Major Depressive Disorder

The purpose of this study is to evaluate how well JNJ-89495120 works (anti-depressant effects) and how well it is tolerated as compared to placebo on reducing the symptoms of depression in participant...

124 participants
Janssen Research & Development, LLC
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About Depression Clinical Trials in Phoenix

Depression (major depressive disorder) is a common and serious mood disorder that negatively affects how you feel, think, and handle daily activities. It affects over 280 million people globally. Treatment includes psychotherapy, antidepressant medications, and brain stimulation therapies.

There are currently 7 depression clinical trials recruiting participants in Phoenix, AZ. These studies are seeking a combined 2,545 participants. Research is being sponsored by Neumora Therapeutics, Inc., Xenon Pharmaceuticals Inc., Alto Neuroscience and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Depression Clinical Trials in Phoenix — FAQ

Are there depression clinical trials in Phoenix?

Yes, there are 7 depression clinical trials currently recruiting in Phoenix, AZ. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Phoenix?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Phoenix research site will contact you about next steps.

Are clinical trials in Phoenix free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Phoenix studies also compensate for your time and travel.

What depression treatments are being tested?

The 7 active trials in Phoenix are testing new therapies including novel drugs, biologics, and treatment approaches for depression.

Data updated March 2, 2026 from ClinicalTrials.gov