NCT06936202 · Arizona State University
Effects of Spirulina Supplementation on Mental Health in Healthy Adults
What this study is about
Spirulina platensis is a form of cyanobacteria, a blue-green algae, and is a superfood most known for being rich in protein, vitamins and minerals, and healthful phytochemicals. Spirulina supports brain health through neuroprotection offered by its antioxidants, anti-inflammatory properties, and hormone regulation.
View original scientific description
Spirulina platensis is a form of cyanobacteria, a blue-green algae, and is a superfood most known for being rich in protein, vitamins and minerals, and healthful phytochemicals. Spirulina supports brain health through neuroprotection offered by its antioxidants, anti-inflammatory properties, and hormone regulation. The aim of this study is to supplement healthy adults from a campus community with 3g of spirulina, daily, for 8 weeks to improve mood and mental acuity in comparison to receiving a placebo.
Interventions
OTHER
Spirulina capsules
active intervention
OTHER
Placebo
no active ingredient
Primary outcome measures
POMS (profile of mood states questionnaire)
Time frame: conducted at baseline and at week 8 (study's end)
A validated measure consisting of 65 brief phrases, asking how they have personally felt over the last week, including today. The participants were asked to carefully rate their response on a 5-point Likert scale, ranging from 'not at all' to 'extremely'.
Trail Making Test
Time frame: conducted at baseline and at week 8 (study's end)
The TMT consists of two iterations - versions A and B - and brief samples of each will be provided for the participant to practice prior to the longer, scored version. This is a timed paper and pencil test requiring the participant to connect a series of numbers and/or letters that are randomly arranged.
Who can participate
This study lists these criteria on ClinicalTrials.gov. A study coordinator reviews eligibility during screening — this page does not determine whether you qualify.
Inclusion criteria
- healthy adults
- no underlying chronic disease or acute conditions
- no autoimmune conditions
- do not consume alcohol in excess, smoke, use recreational drugs
- does not follow restrictive diets
- will be recruited from the ASU university campus.
Exclusion criteria
- not have been clinically diagnosed with depression
- not taking antidepressants, anxiety, or stress medications, or any other medications
- drugs, or supplements that could influence mental capacities
- not pregnant or breastfeeding
- not a competitive athlete
Where
- Phoenix, Arizona
Related conditions & keywords
Frequently asked questions
What is a clinical trial?
A clinical trial is a research study that tests new medical treatments, drugs, devices, or procedures to determine their safety and effectiveness. Trials are carefully designed and monitored to protect participants while advancing medical knowledge.
Is it safe to participate?
Clinical trials follow strict safety guidelines and ethical standards. Trials must be reviewed and approved, and participants are closely monitored by medical professionals throughout the study. You can withdraw at any time if you choose.
Will I be compensated?
Many clinical trials offer compensation for your time, travel expenses, and inconvenience. The specific compensation varies by study and will be discussed during the screening process. All study-related medical care is typically provided at no cost to participants.
Will I receive a placebo instead of treatment?
When effective treatment exists, participants typically receive either the standard treatment plus the study intervention, or the standard treatment plus placebo. You would not be denied effective care. Placebos are primarily used when no proven treatment is available, or in addition to standard care. Your trial consent form will clearly explain what treatments you may receive.
Can I leave a trial if I change my mind?
Absolutely. Participation in clinical trials is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty or loss of benefits to which you are otherwise entitled.
How long does a clinical trial last?
Trial duration varies widely depending on the study design and purpose. Some trials last just a few weeks, while others may continue for months or years. The study coordinator will provide specific timeline information during your screening call.
Data: ClinicalTrials.gov · synced Aug 19, 2025 · Source of record for eligibility and locations