4 Head and Neck Cancer Clinical Trials in Pittsburgh, PA (2026)

Q: How do I join a clinical trial in Pittsburgh?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you.

Recruiting Head and Neck Cancer Studies in Pittsburgh

NCT06305676Recruiting

Biomarker Approach to Screening for the Early Detection of HPV-related Oropharyngeal Cancer (BASH OPC)

Investigators seek to determine the sensitivity and specificity of a combined HPV 16 DNA and host gene methylation oral biomarker panel to distinguish early Oropharyngeal Cancer (OPC) cases from contr...

Pittsburgh, PA400 participantsH. Lee Moffitt Cancer Center and Research Institute

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NCT07423078Recruiting

Window of Opportunity in Preserving Laryngeal Function Trial

This trial will study the safety and tolerability and disease survival rates in adult patients with recurrent/metastatic (R/M) HNSCC when treated with carboplatin or cisplatin, paclitaxel, and toripal...

Pittsburgh, PA87 participantsMatthew Spector

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NCT07156227Recruiting

Testing the Addition of an Anti-Cancer Drug, Camonsertib, to Radiation Therapy for Recurrent Head and Neck Squamous Cell Carcinoma

This phase I trial tests the safety, side effects, and best dose of camonsertib in combination with stereotactic body radiation therapy in controlling disease in patients with head and neck squamous c...

Pittsburgh, PA39 participantsNational Cancer Institute (NCI)

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NCT06052839Recruiting

Pulsed Dose Chemotherapy Plus Pembrolizumab in Recurrent/Metastatic HNSCC

The rationale for the new sequence of pulsed dose chemotherapy proposed in this trial is based on the hypotheses that current standard dosing of chemotherapy plus pembrolizumab ultimately suppresses t...

Pittsburgh, PA15 participantsDan Zandberg

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About Head and Neck Cancer Clinical Trials in Pittsburgh

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 4 head and neck cancer clinical trials recruiting participants in Pittsburgh, PA. These studies are seeking a combined 541 participants. Research is being sponsored by H. Lee Moffitt Cancer Center and Research Institute, Matthew Spector, National Cancer Institute (NCI) and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Pittsburgh — FAQ

Are there head and neck cancer clinical trials in Pittsburgh?

Yes, there are 4 head and neck cancer clinical trials currently recruiting in Pittsburgh, PA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Pittsburgh?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Pittsburgh research site will contact you about next steps.

Are clinical trials in Pittsburgh free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Pittsburgh studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 4 active trials in Pittsburgh are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated July 13, 2026 from ClinicalTrials.gov