8 Chronic Lymphocytic Leukemia Clinical Trials in Rochester, MN (2026)

Q: How do I join a clinical trial in Rochester?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you.

Recruiting Chronic Lymphocytic Leukemia Studies in Rochester

NCT07509151Recruiting

Surovatamig as Consolidation Therapy in Participants With Chronic Lymphocytic Leukaemia or Small Lymphocytic Lymphoma With Unmutated Immunoglobulin Heavy Chain Variable (IGHV)

The purpose of this study is to evaluate the therapeutic benefit and safety of subcutaneous (SC) Surovatamig monotherapy as consolidation therapy in patients with Chronic Lymphocytic Leukaemia (CLL)/ ...

Rochester, MNPHASE3420 participantsAstraZeneca

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NCT05091424Recruiting

A Study Evaluating the Safety, Efficacy, and Pharmacokinetics of Mosunetuzumab and a Combined Regimen of Mosunetuzumab and Venetoclax in Participants With Relapsed or Refractory Chronic Lymphocytic Leukemia

This study will assess the safety, tolerability, pharmaokinetics, and preliminary efficacy of mosunetuzumab (Lunsumio) monotherapy in participants with relapsed or refractory (R/R) chronic lymphocytic...

Rochester, MNPHASE1332 participantsHoffmann-La Roche

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NCT06876662Recruiting

A Study of (LY3527727) Pirtobrutinib in Participants With Previously Treated Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma or Non-Hodgkin Lymphoma

Study J2N-MC-JZ01 (JZ01) is an individual-study appendix (ISA) under master protocol J2N-MC-JZNY, and represents participants from the completed originator study, clinical study LOXO-BTK-18001/J2N-OX-...

Rochester, MNPHASE4279 participantsEli Lilly and Company

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NCT03516617Recruiting

Acalabrutinib With or Without Obinutuzumab in Treating Patients With Early-Stage Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma

This phase II trials studies how well acalabrutinib with or without obinutuzumab works in treating patients with early-stage chronic lymphocytic leukemia or small lymphocytic lymphoma. Acalabrutinib m...

Rochester, MNPHASE2120 participantsMayo Clinic

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NCT07271667Recruiting

A Study of Emavusertib + An Approved Bruton Tyrosine Kinase Inhibitor (BTKi) in Participants With Chronic Lymphocytic Leukemia (CLL) and Other B-cell Malignancies

The primary objective of the study for Cohort 1 and Cohort 2 is to assess the anticancer activity of emavusertib in combination with zanubrutinib in participants with CLL....

Rochester, MNPHASE2108 participantsCuris, Inc.

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NCT06151730Recruiting

Evaluation of Hypertension Management and Cardiovascular Adverse Event Prevention in Patients With B-cell Malignancies Undergoing Treatment With Bruton Tyrosine Kinase Inhibitors, the HALT Study

This study evaluates the incidence and management of new and worsening high blood pressure in patients with B-cell cancers on BTKi treatment....

Rochester, MN100 participantsMayo Clinic

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NCT05876923Recruiting

The Effects of Exercise on Immune Phenotype of Indolent Non-Hodgkin Lymphoma and Chronic Lymphocytic Leukemia Patients

This clinical trial studies the effect of short-term (acute) and long-term (chronic) exercise on immune characteristics and function (phenotype) of patients with indolent non-Hodgkin lymphoma (NHL) an...

Rochester, MNNA70 participantsMayo Clinic

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NCT06536452Recruiting

Hematopoiesis in MBL and CLL Versus Healthy Age-Matched Control Subjects

This study evaluates hematopoiesis to determine how MBL/CLL affected bone marrow responds to fight off infections in the body....

Rochester, MN50 participantsMayo Clinic

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About Chronic Lymphocytic Leukemia Clinical Trials in Rochester

Chronic lymphocytic leukemia (CLL) is a slow-growing cancer of the blood and bone marrow that affects B lymphocytes. It is the most common type of adult leukemia. Treatment options include targeted therapies, chemotherapy, and immunotherapy.

There are currently 8 chronic lymphocytic leukemia clinical trials recruiting participants in Rochester, MN. These studies are seeking a combined 1,479 participants. Research is being sponsored by AstraZeneca, Hoffmann-La Roche, Eli Lilly and Company and 2 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Chronic Lymphocytic Leukemia Clinical Trials in Rochester — FAQ

Are there chronic lymphocytic leukemia clinical trials in Rochester?

Yes, there are 8 chronic lymphocytic leukemia clinical trials currently recruiting in Rochester, MN. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Rochester?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Rochester research site will contact you about next steps.

Are clinical trials in Rochester free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Rochester studies also compensate for your time and travel.

What chronic lymphocytic leukemia treatments are being tested?

The 8 active trials in Rochester are testing new therapies including novel drugs, biologics, and treatment approaches for chronic lymphocytic leukemia.

Data updated October 18, 2026 from ClinicalTrials.gov