San Francisco, CA7 Active Studies

Head and Neck Cancer Clinical Trials in San Francisco, CA

Find 7 actively recruiting head and neck cancer clinical trials in San Francisco, CA. Connect with local research sites and explore new treatment options.

7
Active Trials
7
Sponsors
1,746
Enrolling

Recruiting Head and Neck Cancer Studies in San Francisco

NCT06788990Recruiting

FORTIFI-HN01: A Study of Ficerafusp Alfa (BCA101) or Placebo in Combination With Pembrolizumab in First-Line PD-L1-pos, R or M HNSCC

Ficerafusp alfa is directed against two targets, Epidermal Growth Factor Receptor (EGFR) and Transforming Growth Factor beta (TGF-β). This study intends to evaluate the safety and efficacy of ficeraf...

San Francisco, CAPHASE2650 participantsBicara Therapeutics
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NCT04892173Recruiting

JNJ-90301900 (NBTXR3) Activated by Radiotherapy With or Without Cetuximab in LA-HNSCC

This is a global, open-label, randomized, 2-arm, Investigator's choice Phase 3 (Pivotal Stage) study to investigate the efficacy and safety of JNJ-90301900 (NBTXR3) / radiation therapy (RT)±cetuximab ...

San Francisco, CAPHASE3500 participantsJohnson & Johnson Enterprise Innovation Inc.
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NCT07768189Recruiting

A Study to Evaluate CRB-701 Compared to Investigator's Choice Therapy in Previously Treated Oropharyngeal Squamous Cell Carcinoma

The goal of this study is to understand whether CRB-701, a targeted form of chemotherapy called an anti-body drug conjugate, will work as a treatment for oropharyngeal (throat, tonsil) cancer. In pati...

San Francisco, CAPHASE3260 participantsCorbus Pharmaceuticals Inc.
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NCT03480971Recruiting

Treatment of Radiation and Cisplatin Induced Toxicities with Tempol

A 10 week trial to assess the ability of Tempol to prevent and/or reduce toxicities associated with cisplatin and radiation treatment in head and neck cancer patients. Over the course of the 10 week t...

San Francisco, CAPHASE2120 participantsMatrix Biomed, Inc.
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NCT06457503Recruiting

A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer

This study aims to investigate toripalimab with chemotherapy in participants with nasopharyngeal cancer....

San Francisco, CAPHASE4100 participantsCoherus Oncology, Inc.
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NCT06682442Recruiting

Induction Chemotherapy Response-Guided Radiation for EBV-Associated Nasopharyngeal Carcinoma

This clinical trial tests the effect of induction chemotherapy response-guided radiation (de-escalated intensity-modulated radiation therapy \[IMRT\]) compared to standard IMRT in patients with Epstei...

San Francisco, CANA66 participantsUniversity of California, San Francisco
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NCT06064097Recruiting

A Study Using Nivolumab, in Combination With Chemotherapy Drugs to Treat Nasopharyngeal Carcinoma (NPC)

This phase II trial tests effects of nivolumab in combination with chemotherapy drugs prior to radiation therapy patients with nasopharyngeal carcinoma (NPC). Immunotherapy with monoclonal antibodies,...

San Francisco, CAPHASE250 participantsNational Cancer Institute (NCI)
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About Head and Neck Cancer Clinical Trials in San Francisco

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 7 head and neck cancer clinical trials recruiting participants in San Francisco, CA. These studies are seeking a combined 1,746 participants. Research is being sponsored by Bicara Therapeutics, Johnson & Johnson Enterprise Innovation Inc., Corbus Pharmaceuticals Inc. and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in San Francisco — FAQ

Are there head and neck cancer clinical trials in San Francisco?

Yes, there are 7 head and neck cancer clinical trials currently recruiting in San Francisco, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 7 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated October 8, 2026 from ClinicalTrials.gov