11 Heart Disease Clinical Trials in San Francisco, CA (2026)

Q: How do I join a clinical trial in San Francisco?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you.

Recruiting Heart Disease Studies in San Francisco

NCT04124120Recruiting

Comparison of the Outcomes of Single vs Multiple Arterial Grafts in Women

The central hypothesis of ROMA:Women is that the use of multiple arterial grafting (MAG) will improve clinical outcomes and quality of life (QOL) compared to single arterial grafting (SAG). The speci...

San Francisco, CANA2,300 participantsWeill Medical College of Cornell University

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NCT06959524Recruiting

AGENT DCB STANCE: Safety and Effectiveness Study of AGENT Drug-Coated Balloon Compared to Standard of Care Percutaneous Coronary Intervention (PCI) Treatment for de Novo Coronary Lesions

AGENT DCB STANCE is a prospective, multicenter, open-label, 1:1 randomized controlled study designed to assess the safety and effectiveness of a treatment strategy with the AGENT Drug-Coated Balloon c...

San Francisco, CANA1,616 participantsBoston Scientific Corporation

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NCT06854458Recruiting

The Multicenter Stress Cardiac Magnetic Resonance Quantitative Perfusion Imaging in the United States Study

This research aims to investigate whether symptoms of chest pain or shortness of breath among the study population are arising due to a heart problem, particularly any reduction of blood flow to the h...

San Francisco, CANA1,000 participantsBrigham and Women's Hospital

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NCT06581484Recruiting

Improving Congenital Heart Disease Care

The theory-informed digital health intervention, called as "Empower My Congenital Health (EmpowerMyCH)" aims to activate and engage ACHD patients in building confidence toward navigating the adult hea...

San Francisco, CANA1,000 participantsUniversity of California, San Francisco

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NCT05677880Recruiting

Cerebral Autosomal Dominant Arteriopathy With Subcortical Infarcts and Leukoencephalopathy (CADASIL) Study

This is an observational study to better understand the risk factors and progression of CADASIL, a leading cause of vascular cognitive impairment and dementia (VCID). 575 participants will be enrolled...

San Francisco, CA660 participantsUniversity of Wisconsin, Madison

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NCT05918211Recruiting

Fontan Udenafil Exercise Longitudinal Assessment Trial - 2

This study will evaluate the clinical efficacy and safety of udenafil, an orally administered, potent and selective inhibitor of PDE5, versus placebo for the treatment of adolescent who have had the F...

San Francisco, CAPHASE3436 participantsMezzion Pharma Co. Ltd

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NCT06662500Recruiting

FORWARD CAD IDE Study

The FORWARD CAD IDE Study is a Prospective, Multicenter, Single-Arm, Investigational Device Exemption (IDE) Study conducted to assess the safety and effectiveness of the Shockwave Intravascular Lithot...

San Francisco, CANA408 participantsShockwave Medical, Inc.

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NCT05386173Recruiting

Effect of Fetal Aortic Valvuloplasty on Outcomes

In one of the most severe congenital heart defects, hypoplastic left heart syndrome (HLHS), the left ventricle is underdeveloped and the prognosis is worse than in most other heart defects. The underd...

San Francisco, CA200 participantsQueen Silvia Children's Hospital, Gothenburg, Sweden

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NCT05423158Recruiting

Virtual Care Strategies to Improve Participation in Cardiac Rehabilitation Among Veterans

Home-based CR (HBCR) is an alternative to traditional CR programs that has comparable efficacy in improving morbidity/mortality and increases access to critical services. There is major potential to i...

San Francisco, CAPHASE2150 participantsVA Office of Research and Development

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NCT04715568Recruiting

Secondhand Tobacco Smoke and Cardiovascular Disease

This is a double-blind randomized placebo-controlled crossover clinical trial of efficacy and safety of an FDA-approved angiotensin receptor blocker (losartan) to improve cardiopulmonary outcomes in i...

San Francisco, CAPHASE4100 participantsUniversity of California, San Francisco

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NCT07087184Recruiting

Gauging Outcomes of Total Milk Ingestion on Lipid and gControl

Atherosclerotic cardiovascular disease remains the leading cause of death for adults in the United States. The cardiovascular impact of milk consumption remains a matter of long-standing scientific de...

San Francisco, CANA100 participantsUniversity of California, San Francisco

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About Heart Disease Clinical Trials in San Francisco

Heart disease is the leading cause of death worldwide, encompassing conditions that affect the heart and blood vessels. Coronary artery disease, the most common type, occurs when arteries supplying the heart become narrowed or blocked. Risk factors include high blood pressure, high cholesterol, diabetes, and smoking.

There are currently 11 heart disease clinical trials recruiting participants in San Francisco, CA. These studies are seeking a combined 7,970 participants. Research is being sponsored by Weill Medical College of Cornell University, Boston Scientific Corporation, Brigham and Women's Hospital and 6 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Heart Disease Clinical Trials in San Francisco — FAQ

Are there heart disease clinical trials in San Francisco?

Yes, there are 11 heart disease clinical trials currently recruiting in San Francisco, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What heart disease treatments are being tested?

The 11 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for heart disease.

Data updated July 17, 2026 from ClinicalTrials.gov