San Francisco, CA8 Active Studies

Substance Use Disorder Clinical Trials in San Francisco, CA

Find 8 actively recruiting substance use disorder clinical trials in San Francisco, CA. Connect with local research sites and explore new treatment options.

8
Active Trials
4
Sponsors
4,548
Enrolling

Recruiting Substance Use Disorder Studies in San Francisco

NCT07219953Recruiting

A Study of Brenipatide in Participants With Alcohol Use Disorder

The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with Alcohol Use Disorder (AUD) and hazardous alcohol use. Participation in this study ...

San Francisco, CAPHASE31,100 participantsEli Lilly and Company
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NCT07219966Recruiting

A Study of Brenipatide in Participants With Moderate-to-Severe Alcohol Use Disorder

The purpose of this study is to see if brenipatide when compared to a placebo works and is safe for participants with moderate-to-severe Alcohol Use Disorder (AUD). Participation in this study will la...

San Francisco, CAPHASE31,100 participantsEli Lilly and Company
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NCT04375033Recruiting

A Study Comparing Oral Buprenorphine and Injectable Buprenorphine for the Treatment of Opioid Use Disorder

VA-BRAVE will determine whether a 28-day long-acting injectable sub-cutaneous (in the belly area) formulation of buprenorphine at a target dose of 300mg is superior in retaining Veterans in opioid tre...

San Francisco, CAPHASE4952 participantsVA Office of Research and Development
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NCT06323824Recruiting

Office-based Methadone Versus Buprenorphine to Address Retention in Medication for Opioid Use Disorder Treatment.

The purpose of this clinical trial is to compare the effectiveness of office-based methadone with pharmacy administration and/or dispensing to office-based buprenorphine for the treatment of opioid us...

San Francisco, CAPHASE4600 participantsYale University
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NCT07420283Recruiting

A Study of Brenipatide in Participants With Opioid Use Disorder

The purpose of this study is to see if brenipatide, when compared to placebo, is safe and effective for participants with opioid use disorder, when used with buprenorphine with or without naloxone. T...

San Francisco, CAPHASE2465 participantsEli Lilly and Company
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NCT06872190Recruiting

Using Clinical Decision Support to Provide Social Risk-Informed Care for Opioid Use Disorder in the Emergency Department

The overarching goal of this proposal is to integrate patient social risk information into an existing electronic health record (EHR)-based clinical decision support (CDS) tool (CDSv1) to facilitate e...

San Francisco, CANA300 participantsUniversity of California, San Francisco
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NCT06518785Recruiting

Ultrasound Neuromodulation of the Brain for Alcohol Use Disorder

This study aims to examine the effects of Low-Intensity Focused Ultrasound (LIFU) on brain activity in patients with alcohol use disorder....

San Francisco, CANA25 participantsUniversity of California, San Francisco
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NCT07214467Recruiting

Individualized Adaptive Deep Brain Stimulation in Opioid Use Disorder

The purpose of this study is to determine if personalized (adaptive) Deep Brain Stimulation (DBS) based upon invasive brain mapping is safe and can lead to better outcomes like reductions in craving a...

San Francisco, CANA6 participantsUniversity of California, San Francisco
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About Substance Use Disorder Clinical Trials in San Francisco

Substance use disorder is a condition where the use of substances leads to health issues, disability, and failure to meet responsibilities. It encompasses alcohol, opioid, stimulant, and other drug addictions. Treatment includes behavioral therapy, medication-assisted treatment, and support programs.

There are currently 8 substance use disorder clinical trials recruiting participants in San Francisco, CA. These studies are seeking a combined 4,548 participants. Research is being sponsored by Eli Lilly and Company, VA Office of Research and Development, Yale University and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Substance Use Disorder Clinical Trials in San Francisco — FAQ

Are there substance use disorder clinical trials in San Francisco?

Yes, there are 8 substance use disorder clinical trials currently recruiting in San Francisco, CA. Browse the studies on this page to find one that fits.

How do I join a clinical trial in San Francisco?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the San Francisco research site will contact you about next steps.

Are clinical trials in San Francisco free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many San Francisco studies also compensate for your time and travel.

What substance use disorder treatments are being tested?

The 8 active trials in San Francisco are testing new therapies including novel drugs, biologics, and treatment approaches for substance use disorder.

Data updated July 18, 2026 from ClinicalTrials.gov