4 Head and Neck Cancer Clinical Trials in Scottsdale, AZ (2026)

Q: How do I join a clinical trial in Scottsdale?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Scottsdale research site will contact you.

Recruiting Head and Neck Cancer Studies in Scottsdale

NCT06496178Recruiting

A Phase 3 Study to Evaluate Petosemtamab Compared With Investigator's Choice Monotherapy in Previously Treated Head and Neck Squamous Cell Carcinoma Patients

This is a phase 3 open-label, randomized, controlled, multicenter study to compare petosemtamab vs investigator's choice monotherapy in HNSCC patients for the second- and third-line treatment of incur...

Scottsdale, AZPHASE3600 participantsMerus N.V.

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NCT05541016Recruiting

De-Escalated Adjuvant and Definitive Radiation Therapy Informed by DART 2.0 ctHPV-DNA

This phase II trial examines the use of blood-based biomarkers is to help inform decision making for treatment and radiation therapy for patients with human papillomavirus (HPV) positive oropharyngeal...

Scottsdale, AZPHASE2455 participantsMayo Clinic

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NCT06992427Recruiting

High-dose Prophylactic Gabapentin (HOPE) vs. Placebo to Prevent Opioid Use for Oral Mucositis Pain During Concurrent Chemoradiation for Head and Neck Cancer

This phase III trial tests if gabapentin can prevent the need for opiate pain medication for mouth sores (oral mucositis) in patients undergoing treatment with chemotherapy and radiation for squamous ...

Scottsdale, AZPHASE3228 participantsAlliance for Clinical Trials in Oncology

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NCT06532279Recruiting

Testing the Addition of the Drug BMX-001, a Radioprotector, or a Placebo to the Usual Chemoradiation Therapy for Patients With Head and Neck Cancer

This phase II trial compares the effectiveness of adding BMX-001 to usual symptom management versus usual symptom management alone for reducing oral mucositis in patients who are receiving chemoradiat...

Scottsdale, AZPHASE298 participantsNRG Oncology

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About Head and Neck Cancer Clinical Trials in Scottsdale

Head and neck cancers develop in the mouth, throat, larynx, sinuses, or salivary glands. HPV-related oropharyngeal cancers have been increasing in prevalence. Treatment includes surgery, radiation, chemotherapy, and immunotherapy.

There are currently 4 head and neck cancer clinical trials recruiting participants in Scottsdale, AZ. These studies are seeking a combined 1,381 participants. Research is being sponsored by Merus N.V., Mayo Clinic, Alliance for Clinical Trials in Oncology and 1 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Head and Neck Cancer Clinical Trials in Scottsdale — FAQ

Are there head and neck cancer clinical trials in Scottsdale?

Yes, there are 4 head and neck cancer clinical trials currently recruiting in Scottsdale, AZ. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Scottsdale?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Scottsdale research site will contact you about next steps.

Are clinical trials in Scottsdale free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Scottsdale studies also compensate for your time and travel.

What head and neck cancer treatments are being tested?

The 4 active trials in Scottsdale are testing new therapies including novel drugs, biologics, and treatment approaches for head and neck cancer.

Data updated July 19, 2026 from ClinicalTrials.gov