7 Crohns Disease Clinical Trials in St Louis, MO (2026)

Q: How do I join a clinical trial in St Louis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you.

Recruiting Crohns Disease Studies in St Louis

NCT07184944Recruiting

A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease

This is a multicenter, randomized, double-blind, placebo-controlled, maintenance, Phase 3 study to evaluate the efficacy and safety of duvakitug in participants with moderately to severely active Croh...

St Louis, MOPHASE3751 participantsSanofi

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NCT04844606Recruiting

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks ...

St Louis, MOPHASE3150 participantsEli Lilly and Company

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NCT06976853Recruiting

Moving Beyond Inflammation as a Therapeutic Target for Crohn's Disease

The purpose of this research study is to evaluate what type of treatment will be beneficial for people with Crohn's disease and difficult to treat inflammation in the small bowel. Current therapies ar...

St Louis, MOPHASE260 participantsWashington University School of Medicine

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NCT06670638Recruiting

Development of a Novel Endoscopic Index and Patient-reported Outcome Measure for Clinical Trials in Participants With Permanent Ileostomy

To date, patients with Crohn's Disease (CD) and permanent ileostomies have been excluded from clinical trials for new treatments. To allow this patient population to be included in clinical trials, ou...

St Louis, MO50 participantsAlimentiv Inc.

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NCT06721962Recruiting

Treatment of Moderate to Severe Refractory Crohn's Disease

This research study is testing an investigational research product called TRX103 as a possible treatment for individuals suffering from Crohn's Disease (CD). The primary purpose of this study is to le...

St Louis, MOPHASE139 participantsTr1X, Inc.

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NCT06918808Recruiting

DB-3Q bmMSC-EVs in Patients With Perianal Fistulizing Crohn's Disease

This is a double-blind, randomized, placebo-controlled, sequential cohort, ascending dose clinical trial to evaluate the safety and determine the efficacy of ascending doses of DB-3Q for the treatment...

St Louis, MOPHASE236 participantsDirect Biologics, LLC

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NCT07368972Recruiting

Study of DISC-0974-201 in Participants With IBD and Anemia

This is a Phase 2, multicenter, randomized, double-blind placebo-controlled study of DISC-0974 to evaluate safety, tolerability, and efficacy in participants with IBD and anemia of inflammation....

St Louis, MOPHASE221 participantsDisc Medicine, Inc

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About Crohns Disease Clinical Trials in St Louis

Crohn's disease is a chronic inflammatory bowel disease that causes inflammation anywhere in the digestive tract, most commonly in the small intestine and colon. Symptoms include abdominal pain, diarrhea, fatigue, and weight loss. Treatment includes anti-inflammatory drugs, immunosuppressants, biologics, and surgery.

There are currently 7 crohns disease clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 1,107 participants. Research is being sponsored by Sanofi, Eli Lilly and Company, Washington University School of Medicine and 4 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Crohns Disease Clinical Trials in St Louis — FAQ

Are there crohns disease clinical trials in St Louis?

Yes, there are 7 crohns disease clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in St Louis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.

Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.

What crohns disease treatments are being tested?

The 7 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for crohns disease.

Data updated July 18, 2026 from ClinicalTrials.gov