22 Ulcerative Colitis Clinical Trials in St Louis, MO (2026)

Q: Are there ulcerative colitis clinical trials in St Louis?

Yes, there are 22 ulcerative colitis clinical trials currently recruiting in St Louis, MO.

Q: How do I join a clinical trial in St Louis?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you.

Q: Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatments, medical tests, and doctor visits are provided at no cost.

Recruiting Ulcerative Colitis Studies in St Louis

NCT06456554Recruiting

Acellular Dermal Matrix Investigation in Breast Reconstruction

Prospective, multi-center, dual-arm non-randomized clinical study in females undergoing a two-stage breast reconstruction using a pre-pectoral technique....

St Louis, MONA467 participantsRTI Surgical

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NCT03373968Recruiting

Givinostat in Duchenne's Muscular Dystrophy Long-term Safety and Tolerability Study

This is an open label, long-term safety, tolerability, and efficacy study of GIVINOSTAT in all DMD (Duchenne's muscular dystrophy) patients who have been previously treated in one of the GIVINOSTAT st...

St Louis, MOPHASE2206 participantsItalfarmaco

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NCT07644559Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Pancreatic Cancer

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab in patients with metastatic KRAS G12D - mutated Pancreatic Cancer...

St Louis, MOPHASE2180 participantsVerastem, Inc.

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NCT05685485Recruiting

Tied Tube Trial in Glaucoma Surgery

The aim of this study is to assess whether delaying early flow through the Ahmed tube shunt may improve the post-operative surgical outcomes and provide a more predictable outcome. To assess this the ...

St Louis, MO152 participantsWashington University School of Medicine

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NCT04844606Recruiting

A Master Protocol (AMAZ): A Study of Mirikizumab (LY3074828) in Pediatric Participants With Ulcerative Colitis or Crohn's Disease (SHINE-ON)

The main purpose of this study is to evaluate the long-term efficacy of mirikizumab in pediatric participants with ulcerative colitis (UC) or Crohn's disease (CD). The study will last about 172 weeks ...

St Louis, MOPHASE3150 participantsEli Lilly and Company

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NCT06571669Recruiting

BOOM-IBD2 Pivotal Clinical Trial

Ulcerative colitis is a long-lasting condition that causes swelling and sores in the large intestine. This study tests whether a small device placed under the skin can help reduce bowel urgency in peo...

St Louis, MONA137 participantsBoomerang Medical

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NCT06710756Recruiting

Lead-212 PSV359 Therapy for Patients With Solid Tumors

Phase I/IIa image-guided, alpha-particle therapy study of \[203Pb\]Pb-PSV359 and \[212Pb\]Pb-PSV359 in patients with solid tumors that are known to be Fibroblast Activation Protein (FAP)-positive....

St Louis, MOPHASE1112 participantsPerspective Therapeutics

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NCT04626674Recruiting

A Gene Transfer Therapy Study to Evaluate the Safety of and Expression From Delandistrogene Moxeparvovec (SRP-9001) in Participants With Duchenne Muscular Dystrophy (DMD) - Non-Ambulatory Cohort

Cohort 8 (non-ambulatory participants) is currently enrolling new participants. Enrollment for Cohorts 1 through 7 has been completed. This is an open-label gene transfer therapy study evaluating the...

St Louis, MOPHASE183 participantsSarepta Therapeutics, Inc.

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NCT06830109Recruiting

Nasal Obstruction With Oxymetazoline and Corticosteroids

This study aims to examine the efficacy and safety of commination oxymetazoline/intranasal steroids for long-term management of chronic nasal obstruction that is recalcitrant to the current standard o...

St Louis, MOPHASE280 participantsWashington University School of Medicine

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NCT06904378Recruiting

ONT01 and Gemcitabine/Nab-paclitaxel as Second Line Therapy for Metastatic Pancreatic Ductal Adenocarcinoma

The investigators hypothesize that CD11b agonism reprograms the tumor microenvironment (TME) to overcome resistance to checkpoint immunotherapy in pancreatic ductal adenocarcinoma (PDAC). Therefore, t...

St Louis, MOPHASE161 participantsWashington University School of Medicine

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NCT06138639Recruiting

A Study of SGT-003 Gene Therapy in Duchenne Muscular Dystrophy (INSPIRE DUCHENNE)

This is a multicenter, open-label, non-randomized study to investigate the safety, tolerability, and efficacy of a single intravenous (IV) infusion of SGT-003 in participants with Duchenne muscular dy...

St Louis, MOPHASE160 participantsSolid Biosciences Inc.

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NCT07074288Recruiting

Obstructive Sleep Apnea Non-PAP Outcomes and Viable Alternatives

OSANOVA is a non-randomized clinical trial which aims to compare outcomes of mandibular advancement device (MAD) and hypoglossal nerve stimulation (HGNS) therapies in moderate-to-severe OSA patients w...

St Louis, MONA60 participantsWashington University School of Medicine

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NCT06648434Recruiting

MK2 Inhibitor in Combination With mFOLFIRINOX for Untreated Metastatic Pancreatic Ductal Adenocarcinoma

The investigators hypothesize that MK2 inhibition may improve efficacy of mFOLFIRINOX chemotherapy for patients with pancreatic ductal adenocarcinoma (PDAC)....

St Louis, MOPHASE151 participantsWashington University School of Medicine

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NCT07287189Recruiting

Phase 2 Study of SAT-3247 in Pediatric Ambulatory Patients

Phase 2a trial of SAT-3247 in ambulatory DMD patients aged ≥ 7 and \< 10 years. The trial will study two doses of SAT-3247 in a randomized, double-blind, placebo-controlled weekday regimen for 12 week...

St Louis, MOPHASE251 participantsSatellos Bioscience, Inc.

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NCT07450859Recruiting

A Study of Nuzefatide Pevedotin (BT5528) in Patients With Metastatic Pancreatic Ductal Adenocarcinoma (PDAC)

This is a Phase 2 study for nuzefatide pevedotin (BT5528) in adults with a specific type of pancreatic cancer called metastatic pancreatic ductal adenocarcinoma (PDAC) that has spread and worsened aft...

St Louis, MOPHASE239 participantsBicycleTx Limited

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NCT06835387Recruiting

Study of NALIRIFOX in Advanced Unresectable Small Bowel Tumors

The study regimen will be administered on an outpatient basis and all medications are administered intravenously (IV). Subjects will receive treatment on Day 1 and Day 15 of each 28-day cycle consisti...

St Louis, MOPHASE236 participantsTiago Biachi de Castria

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NCT07492420Recruiting

MedCline Investigational Study for the Treatment of Mild OSA With Positional Therapy

The purpose of this study is to evaluate the safety and effectiveness of the MedCline Sleep System in reducing symptoms related to mild OSA....

St Louis, MONA35 participantsAmenity Health, Inc.

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NCT07132307Recruiting

Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through Mandibular Advancement

The purpose of this study is to evaluate the effectiveness, feasibility, and safety of mandibular advancement devices (MAD) for treating severe obstructive sleep apnea (OSA) in patients who are CPAP i...

St Louis, MONA30 participantsWashington University School of Medicine

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NCT07368972Recruiting

Study of DISC-0974-201 in Participants With IBD and Anemia

This is a Phase 2, multicenter, randomized, double-blind placebo-controlled study of DISC-0974 to evaluate safety, tolerability, and efficacy in participants with IBD and anemia of inflammation....

St Louis, MOPHASE221 participantsDisc Medicine, Inc

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NCT05642455Recruiting

SPEARHEAD-3 Pediatric Study

This is a pediatric basket study to investigate the safety and efficacy of afamitresgene autoleucel in HLA-A\*02 eligible and MAGE-A4 positive subjects aged 2-17 years of age with advanced cancers....

St Louis, MOPHASE120 participantsAdaptimmune

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NCT04318717Recruiting

Pembrolizumab and Hypofractionated Radiation Therapy for the Treatment of Mucosal Melanoma

This is an open-label, single center, one cohort, non-randomized, phase II study. The aim is to evaluate the efficacy and safety of the combination of hypofractionated radiotherapy (HRT) and pembroliz...

St Louis, MOPHASE220 participantsWashington University School of Medicine

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NCT07429240Recruiting

PBGENE-DMD Phase 1/2a Safety and Preliminary Efficacy Study in Duchenne Muscular Dystrophy (FUNCTION-DMD)

The purpose of this Phase 1/2a trial is to evaluate the safety, tolerability, and preliminary efficacy of PBGENE-DMD in patients with DMD harboring mutations amenable to excision of exons 45-55. Given...

St Louis, MOPHASE118 participantsPrecision BioSciences, Inc.

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About Ulcerative Colitis Clinical Trials in St Louis

Ulcerative colitis is a chronic inflammatory bowel disease that causes inflammation and ulcers in the innermost lining of the colon and rectum. It typically presents with bloody diarrhea, abdominal pain, and urgency. Treatment includes aminosalicylates, corticosteroids, immunosuppressants, and biologics.

There are currently 22 ulcerative colitis clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 2,069 participants. Research is being sponsored by RTI Surgical, Italfarmaco, Verastem, Inc. and 13 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Ulcerative Colitis Clinical Trials in St Louis — FAQ

Are there ulcerative colitis clinical trials in St Louis?

Yes, there are 22 ulcerative colitis clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in St Louis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.

Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.

What ulcerative colitis treatments are being tested?

The 22 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for ulcerative colitis.

Data updated July 18, 2026 from ClinicalTrials.gov