St Louis, MO12 Active Studies

Lymphoma Clinical Trials in St Louis, MO

Find 12 actively recruiting lymphoma clinical trials in St Louis, MO. Connect with local research sites and explore new treatment options.

12
Active Trials
11
Sponsors
3,021
Enrolling

Recruiting Lymphoma Studies in St Louis

RecruitingSt Louis, MONCT03075696

A Dose Escalation Study of Glofitamab (RO7082859) as a Single Agent and in Combination With Obinutuzumab, Administered After a Fixed, Single Pre-treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-cell Non-hodgkin's Lymphoma

This is a Phase I/II, multicenter, open-label, dose-escalation study designed to evaluate the efficacy, safety, tolerability and pharmacokinetics (PK) of a novel T-Cell bispecific (TCB), glofitamab, a...

920 participants
Hoffmann-La Roche
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RecruitingSt Louis, MONCT03888105

A Study to Assess the Anti-Tumor Activity and Safety of Odronextamab in Adult Patients With B-cell Non-Hodgkin Lymphoma Who Have Been Previously Treated With Other Cancer Therapies

This study is researching an investigational drug, odronextamab, in adult patients B-cell non-Hodgkin's lymphoma (B-NHL). The main purpose of this study is to assess the effectiveness of odronextamab...

576 participants
Regeneron Pharmaceuticals
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RecruitingSt Louis, MONCT04077723

A Study to Evaluate the Safety, Pharmacokinetics and Preliminary Anti-Tumor Activity of Englumafusp Alfa in Combination With Obinutuzumab and in Combination With Glofitamab Following a Pre-Treatment Dose of Obinutuzumab in Participants With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma

This is a phase I/II, open-label, dose-escalation study designed to evaluate the safety, tolerability, and efficacy of englumafusp alfa (RO7227166) in participants with relapsed/refractory Non-Hodgkin...

498 participants
Hoffmann-La Roche
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RecruitingSt Louis, MONCT06526793

AZD0486 as Monotherapy in Participants With Relapsed/Refractory (R/R) B-cell NHL

This is a Phase 2 global, multi-center, open-label study to assess the efficacy, safety and tolerability of AZD0486 monotherapy in adult participants with relapsed/refractory B-cell non-Hodgkin lympho...

240 participants
AstraZeneca
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RecruitingSt Louis, MONCT06088654

Phase1/2 Study of IPH6501 in Patients With Relapsed /Refractory B-Cell Non-Hodgkin Lymphoma

This is an international, first-in-human, multicenter, open-label Phase 1/2 study to evaluate the safety profile, tolerability of IPH6501, and determine the recommended phase 2 dose (RP2D) for patient...

184 participants
Innate Pharma
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RecruitingSt Louis, MONCT06238648

Epcoritamab Compared to Observation for Treating B-cell Lymphoma Patients Not in Complete Remission After CD19-directed CAR-T Therapy

This phase II trial compares epcoritamab to standard practice (observation) for the treatment of patients with B-cell lymphomas who are not in complete remission after treatment with CD19-directed chi...

120 participants
Academic and Community Cancer Research United
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RecruitingSt Louis, MONCT05643742

A Safety and Efficacy Study Evaluating CTX112 in Subjects With Relapsed or Refractory B-Cell Malignancies

This is an open-label, multicenter, Phase 1/2 study evaluating the safety and efficacy of CTX112â„¢ in subjects with relapsed or refractory B-cell malignancies....

120 participants
CRISPR Therapeutics AG
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RecruitingSt Louis, MONCT05721222

Trial of PRO1160 (GEN1160) in Relapsed or Refractory Non-Hodgkin Lymphoma (NHL) (PRO1160-001)

Brief Summary: This study will test the safety, including side effects, and determine the characteristics of a drug called GEN1160 (PRO1160) in participants with solid tumors and blood cancers. Part...

110 participants
Genmab
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RecruitingSt Louis, MONCT06634589

A Study to Investigate Safety and Effectiveness of BGB-16673 in Combination With Other Agents in Participants With Relapsed or Refractory B-Cell Malignancies

The purpose of this study is to measure the safety, preliminary antitumor activity, pharmacokinetics, and pharmacodynamics with BGB-16673 in combination with other agents in participants with relapsed...

80 participants
BeiGene
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RecruitingSt Louis, MONCT06470451

Confirmatory Study of Topical HyBryteâ„¢ vs. Placebo for the Treatment of CTCL

To evaluate the use of HyBryte, a topical photosensitizing agent, to treat patients with patch/plaque phase cutaneous T-cell lymphoma (mycosis fungoides)....

80 participants
Soligenix
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RecruitingSt Louis, MONCT05896163

A Study to Learn About the Effects of Two Study Medicines (Maplirpacept [PF-07901801] And Glofitamab) When Given Together In People With Relapsed Or Refractory Diffuse Large B Cell Lymphoma.

The purpose of this study is to learn about the effects of two study medicines (maplirpacept \[PF-07901801\] and glofitamab) when given together for the treatment of diffuse large B-cell lymphoma (DLB...

70 participants
Pfizer
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RecruitingSt Louis, MONCT06390956

Pirtobrutinib in Combination With Rituximab in Adults With Untreated Marginal Zone Lymphoma (PIONEER-MZL)

The purpose of this clinical trial is to learn if the drugs Pirtobrutinib and Rituximab are effective for the treatment of newly diagnosed marginal zone lymphoma....

23 participants
University of Utah
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About Lymphoma Clinical Trials in St Louis

Lymphoma is a cancer of the lymphatic system that affects infection-fighting cells called lymphocytes. The two main types are Hodgkin lymphoma and non-Hodgkin lymphoma. Treatment often includes chemotherapy, radiation, immunotherapy, and in some cases stem cell transplant.

There are currently 12 lymphoma clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 3,021 participants. Research is being sponsored by Hoffmann-La Roche, Regeneron Pharmaceuticals, AstraZeneca and 8 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Lymphoma Clinical Trials in St Louis — FAQ

Are there lymphoma clinical trials in St Louis?

Yes, there are 12 lymphoma clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.

How do I join a clinical trial in St Louis?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.

Are clinical trials in St Louis free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.

What lymphoma treatments are being tested?

The 12 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for lymphoma.

Data updated March 2, 2026 from ClinicalTrials.gov