Recruiting Sarcoma Studies in St Louis
NRSTS2021, A Risk Adapted Study Evaluating Maintenance Pazopanib, Limited Margin, Dose-Escalated Radiation Therapy and Selinexor in Non-Rhabdomyosarcoma Soft Tissue Sarcoma (NRSTS)
The study participant has been diagnosed with non-rhabdomyosarcoma (NRSTS). Primary Objectives Intermediate-Risk * To estimate the 3-year event-free survival for intermediate-risk patients treated ...
Treatment of Metastatic Soft Tissue Sarcoma (STS) Patients (FIBROSARC USA)
The present study is an open-label, randomized, controlled, two-arm multi-center study of the efficacy of L19TNF treatment in combination with doxorubicin versus doxorubicin alone in metastatic leiomy...
A Multi-Institution Study of TGFβ Imprinted, Ex Vivo Expanded Universal Donor NK Cell Infusions as Adoptive Immunotherapy in Combination With Gemcitabine and Docetaxel in Patients With Relapsed or Refractory Pediatric Bone and Soft Tissue
The purpose of this study is to determine if the addition of infusions of a type of immune cell called a "natural killer", or NK cell to the sarcoma chemotherapy regimen GEM/DOX (gemcitabine and docet...
Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration
This is a single-arm, phase II study that will enroll a total of 45 subjects. All subjects will have a confirmed diagnosis of metastatic or unresectable soft tissue sarcoma or bone sarcoma. All subjec...
Trial of Ixazomib for Kaposi Sarcoma
This phase II trial studies how well ixazomib works in treating patients with Kaposi sarcoma. Ixazomib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth....
Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma
In this study, patients with soft tissue sarcoma (STS) will receive ADI-PEG 20 and ifosfamide in combination with radiation as neoadjuvant therapy. In phase I of the study, up to 5 dose levels will be...
About Sarcoma Clinical Trials in St Louis
Sarcomas are rare cancers that arise in bone and soft tissues including muscle, fat, blood vessels, and connective tissue. There are more than 70 subtypes of sarcoma. Treatment usually involves surgery combined with radiation and/or chemotherapy.
There are currently 6 sarcoma clinical trials recruiting participants in St Louis, MO. These studies are seeking a combined 423 participants. Research is being sponsored by St. Jude Children's Research Hospital, Philogen S.p.A., Nationwide Children's Hospital and 3 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.
Sarcoma Clinical Trials in St Louis — FAQ
Are there sarcoma clinical trials in St Louis?
Yes, there are 6 sarcoma clinical trials currently recruiting in St Louis, MO. Browse the studies on this page to find one that fits.
How do I join a clinical trial in St Louis?
Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the St Louis research site will contact you about next steps.
Are clinical trials in St Louis free?
Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many St Louis studies also compensate for your time and travel.
What sarcoma treatments are being tested?
The 6 active trials in St Louis are testing new therapies including novel drugs, biologics, and treatment approaches for sarcoma.
Data updated March 2, 2026 from ClinicalTrials.gov