12 Colorectal Cancer Clinical Trials in Tampa, FL (2026)

Q: How do I join a clinical trial in Tampa?

Browse available studies, click one that interests you, and complete the free eligibility form. A study coordinator at the Tampa research site will contact you.

Recruiting Colorectal Cancer Studies in Tampa

NCT02328677Recruiting

ColoCare Study - Colorectal Cancer Cohort

ColoCare is an international prospective cohort study of stage I-IV colorectal cancer patients (ICD-10 C18-C20)....

Tampa, FL5,000 participantsUniversity of Utah

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NCT06445062Recruiting

Study of RAS(ON) Inhibitors in Patients With Gastrointestinal Solid Tumors

The purpose of this platform study is to evaluate the safety, tolerability, pharmacokinetics (PK), and preliminary antitumor activity of novel RAS(ON) inhibitors combined with Standard(s) of Care (SOC...

Tampa, FLPHASE11,130 participantsRevolution Medicines, Inc.

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NCT07221357Recruiting

A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer

The purpose of this study is to evaluate the safety and efficacy of pumitamig in combination with chemotherapy versus bevacizumab in combination with chemotherapy in participants with previously untre...

Tampa, FLPHASE2990 participantsBristol-Myers Squibb

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NCT06745895Recruiting

Multilevel Action Toward Colorectal Cancer and Hepatitis C Education and Screening

This innovative Multilevel Action Toward Colorectal Cancer (CRC) and Hepatitis C Virus (HCV) Education and Screening (MATCHES) intervention aims to promote concurrent HCV and CRC screening among FQHC ...

Tampa, FLNA350 participantsH. Lee Moffitt Cancer Center and Research Institute

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NCT05379595Recruiting

A Study of Amivantamab Monotherapy and in Addition to Standard-of-Care Chemotherapy in Participants With Advanced or Metastatic Colorectal Cancer

The purpose of this study is to assess the anti-tumor activity of amivantamab as a monotherapy (Cohorts A, B, and C), to assess the recommended phase 2 combination dose (RP2CD) of amivantamab when add...

Tampa, FLPHASE1225 participantsJanssen Research & Development, LLC

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NCT07659795Recruiting

A Phase 2 Study of VS-7375 in Patients With KRAS G12D-Mutated Colorectal Cancer

This study will assess the safety and efficacy of VS-7375 alone and in combination with cetuximab or panitumumab and cetuximab plus mFOLFOX in patients with metastatic KRAS G12D - mutated Colorectal C...

Tampa, FLPHASE2150 participantsVerastem, Inc.

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NCT07023289Recruiting

A Study to Assess Adverse Events and Change in Disease Activity in Adult Participants Receiving Intravenously Infused Telisotuzumab Adizutecan Alone or With Standard of Care in Participants With Post Adjuvant Circulating Tumor DNA Positive Colorectal Cancer and No Radiographic Evidence of Disease

Colorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide. The purpose of this study is to assess change in disease activity when telisotuzumab adizutecan is given alone comp...

Tampa, FLPHASE2140 participantsAbbVie

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NCT06607458Recruiting

Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease

The goal of this clinical trial is to learn if using a liver-directed therapy with high dose chemotherapy followed by approved cancer treatment to treat patients with colorectal cancer that has spread...

Tampa, FLPHASE290 participantsDelcath Systems Inc.

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NCT03692429Recruiting

alloSHRINK - Standard cHemotherapy Regimen and Immunotherapy With Allogeneic NKG2D-based CYAD-101 Chimeric Antigen Receptor T-cells

The purpose of the alloSHRINK study is to assess the safety, cell kinetics and clinical activity of CYAD-101 in patients with unresectable metastatic colorectal cancer administered after standard chem...

Tampa, FLPHASE149 participantsCelyad Oncology SA

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NCT06553885Recruiting

Ph II Study of Enfortumab Vedotin in Patients With Advanced or Metastatic CRC or HCC

This study is a multi-indication, open-label, single-treatment arm, parallel-cohort phase II study of enfortumab vedotin in adult participants with advanced or metastatic colorectal cancer (CRC) or he...

Tampa, FLPHASE240 participantsH. Lee Moffitt Cancer Center and Research Institute

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NCT04991948Recruiting

Study of Pembrolizumab Treatment After CYAD-101 With FOLFOX Preconditioning in Metastatic Colorectal Cancer

The purpose of the CYAD-101-002 study is to assess the safety and clinical activity of CYAD-101 in patients with unresectable metastatic colorectal cancer administered concurrently with FOLFOX chemoth...

Tampa, FLPHASE134 participantsCelyad Oncology SA

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NCT06380101Recruiting

Evaluating a Nonessential Amino Acid Restriction (NEAAR) Medical Food With Total Neoadjuvant Therapy for Locally Advanced Rectal Cancer (LARC)

This clinical study aims to assess feasibility, safety, tolerability, and compliance of a Nonessential Amino Acid Restriction (NEAAR) medical food in adult patients with locally advanced rectal cancer...

Tampa, FLNA30 participantsUniversity of South Florida

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About Colorectal Cancer Clinical Trials in Tampa

Colorectal cancer starts in the colon or rectum and is the third most common cancer diagnosed in both men and women. Early detection through screening significantly improves outcomes. Treatments include surgery, chemotherapy, radiation, and targeted therapies.

There are currently 12 colorectal cancer clinical trials recruiting participants in Tampa, FL. These studies are seeking a combined 8,228 participants. Research is being sponsored by University of Utah, Revolution Medicines, Inc., Bristol-Myers Squibb and 7 other organizations. Clinical trial participation is free and participants receive study-related medical care at no cost.

Colorectal Cancer Clinical Trials in Tampa — FAQ

Are there colorectal cancer clinical trials in Tampa?

Yes, there are 12 colorectal cancer clinical trials currently recruiting in Tampa, FL. Browse the studies on this page to find one that fits.

How do I join a clinical trial in Tampa?

Browse the studies listed above, click one that interests you, and complete the free eligibility form. A study coordinator at the Tampa research site will contact you about next steps.

Are clinical trials in Tampa free?

Yes, clinical trial participation is always free. Study-related treatment, medical tests, and doctor visits are provided at no cost. Many Tampa studies also compensate for your time and travel.

What colorectal cancer treatments are being tested?

The 12 active trials in Tampa are testing new therapies including novel drugs, biologics, and treatment approaches for colorectal cancer.

Data updated September 1, 2026 from ClinicalTrials.gov