Boston, MANCT05407441Now EnrollingIRB Ready

Rhabdoid Tumor Clinical Trial in Boston, MA

Access cutting-edge rhabdoid tumor treatment through this clinical trial at a research site in Boston. Study-provided care at no cost to qualified participants.

Sponsored by Susan Chi, MD

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Expert Care in Boston

Access rhabdoid tumor specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related rhabdoid tumor treatment provided free

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Check if you qualify for this rhabdoid tumor clinical trial in Boston, MA

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Boston

    Convenient for MA residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Boston site if eligible
  4. 4Begin participation

About This Rhabdoid Tumor Study in Boston

This research study involves a combination of three drugs given together as a possible treatment for malignant rhabdoid tumor, atypical teratoid rhabdoid tumor, epithelioid sarcoma, chordoma or other tumors that are deficient in one of two possible proteins, either INI-1 (SMARCB1) or SMARCA4. The names of the study drugs involved in this study are: * Tazemetostat (TAZVERIK) * Nivolumab (OPDIVO) * Ipilimumab (YERVOY)

Sponsor: Susan Chi, MD

Who Can Participate

Inclusion Criteria

Diagnosis: Histologically confirmed tumors at diagnosis or at relapse (as applicable):
Atypical Teratoid Rhabdoid Tumor (ATRT)
Other INI1- or SMARCA4-deficient primary CNS malignant tumors (with PI approval)
Malignant rhabdoid tumor (MRT)
Rhabdoid tumor of the kidney (RTK)
Epithelioid sarcoma
Chordoma (poorly differentiated or de-differentiated)
Other INI1- or SMARCA4-deficient malignant tumors (with PI approval)
All subjects must have had tumor assessment at original diagnosis or relapse showing either of the following: Loss of INI1 confirmed by immunohistochemistry (IHC) OR molecular confirmation of tumor bi-allelic SMARCB1 (INI1) loss or mutation when INI1 IHC is equivocal or unavailable
Loss of SMARCA4 confirmed by IHC OR molecular confirmation of tumor SMARCA4 loss or mutation (with PI approval) Reports confirming these findings (including tumor sequencing if available) will be reviewed by the Sponsor

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Boston?

Yes, this clinical trial (NCT05407441) has an active research site in Boston, MA that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Rhabdoid Tumor Treatment Options in Boston, MA

If you're searching for rhabdoid tumor treatment options in Boston, MA, this clinical trial (NCT05407441) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Boston research site is actively enrolling participants for this clinical trial. You'll receive care from experienced rhabdoid tumor specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all rhabdoid tumor clinical trials near you to find additional studies recruiting in your area.

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