Chapel Hill, NCNCT06312683Now EnrollingIRB Ready

Pouchitis Clinical Trial in Chapel Hill, NC

Access cutting-edge pouchitis treatment through this clinical trial at a research site in Chapel Hill. Study-provided care at no cost to qualified participants.

Sponsored by University of North Carolina, Chapel Hill

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Expert Care in Chapel Hill

Access pouchitis specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related pouchitis treatment provided free

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Check if you qualify for this pouchitis clinical trial in Chapel Hill, NC

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Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to Chapel Hill

    Convenient for NC residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit Chapel Hill site if eligible
  4. 4Begin participation

About This Pouchitis Study in Chapel Hill

Although many people will develop recurrent pouchitis (inflammation of the ileal pouch-anal anastomosis or J-pouch after colectomy for ulcerative colitis) after an initial episode of pouchitis, there are currently no effective treatments to prevent recurrent pouchitis. The goal of this study is to evaluate the potential for rifaximin, an antibiotic, to prevent recurrent pouchitis after treatment for an initial episode of pouchitis. In this study, all patients will be given daily rifaximin for on

Sponsor: University of North Carolina, Chapel Hill

Who Can Participate

Inclusion Criteria

Informed consent will be obtained before any study-related procedures
Age \> 18 and \<75 years
Participants with a proven history of ulcerative colitis and history of 1,2, modified -2 or 3 stage Ileal pouch anal anastomosis (IPAA) and ileostomy takedown
Diagnosis of initial episode of pouchitis within the first 12 months after ileostomy takedown/final stage of IPAA surgery

Exclusion Criteria

Known hypersensitivity to rifaximin or its metabolites
Known Crohn's disease
History of perianal fistula
Known incontinence due to anal sphincter dysfunction
Known irritable pouch syndrome
Active ongoing pelvic infection/sepsis at baseline visit
New onset of high bowel frequency in the setting of acute pouchitis in the first 4 weeks after IPAA
Known Clostridoides difficile infection
Need for antibiotic long-term therapy (e.g. doxycycline for acne)
Known active Hepatitis B, C, HIV
Clinically significant liver disease (Primary Sclerosing Cholangit

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in Chapel Hill?

Yes, this clinical trial (NCT06312683) has an active research site in Chapel Hill, NC that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Pouchitis Treatment Options in Chapel Hill, NC

If you're searching for pouchitis treatment options in Chapel Hill, NC, this clinical trial (NCT06312683) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our Chapel Hill research site is actively enrolling participants for this clinical trial. You'll receive care from experienced pouchitis specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all pouchitis clinical trials near you to find additional studies recruiting in your area.

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Secure · Expert Care · Chapel Hill, NC