New York, NYNCT06793488Now EnrollingIRB Ready

Alcohol Use Disorder Clinical Trial in New York, NY

Access cutting-edge alcohol use disorder treatment through this clinical trial at a research site in New York. Study-provided care at no cost to qualified participants.

Sponsored by Columbia University

Quick Self-Assessment

See if you qualify for this New York location

Preparing your pre-screening questions…

Expert Care in New York

Access alcohol use disorder specialists at no cost

IRB Approved

This study follows strict safety protocols and ethical guidelines

No-Cost Care

All study-related alcohol use disorder treatment provided free

Apply for This New York Location

Check if you qualify for this alcohol use disorder clinical trial in New York, NY

Secure & Confidential

Your information is protected and will only be shared with the research team.

Why Participate?

  • No-Cost Study Care

  • Local to New York

    Convenient for NY residents

  • Cutting-Edge Treatment

    Access to innovative therapies

  • Expert Medical Care

    Close monitoring by specialists

  • Possible Compensation*

    For time and travel

*Compensation varies by study. Confirm details with coordinator.

Simple Process

  1. 1Submit this form
  2. 2Phone screening
  3. 3Visit New York site if eligible
  4. 4Begin participation

About This Alcohol Use Disorder Study in New York

The goal of this study is to better understand the underlying neurobiological basis of anxiety that emerges during abstinence in patients with alcohol use disorder (AUD). The main questions it aims to answer are: 1. To characterize anxiety itself as well as anxiety related-neurobiological circuitry in early abstinence in AUD 2. To examine how anxiety and anxiety related-neurobiological circuitry change over the course of abstinence in AUD Researchers will recruit both participants with AUD and healthy volunteers. The participants with AUD will be prescribed disulfiram, a medication that helps participants with AUD stay abstinent. Healthy volunteers will not receive antabuse. Patients with AUD will undergo fMRI scanning both after 1 week and 3 months of disulfiram treatment. Healthy volunteers will undergo fMRI once.

Sponsor: Columbia University

Who Can Participate

Inclusion Criteria

(Participants with Alcohol use Disorder):
Between the ages of 21 and 55
Right-handed
Able to perform informed consent and comply with study
Seeking treatment for AUD
Meets The Diagnostic and Statistical Manual of Mental Disorders (DSM-5) criteria for AUD of at least moderate severity (\>3 symptoms) Inclusion Criteria (Healthy Volunteer Participants):
Between the ages of 21 and 55
Right-handed
Able to perform informed consent and comply with study
Report drinking an average of fewer than 8/15 standard drinks per week for women/men and no more than 1 HDD (heavy drinking days) during the previous 28 days.

Exclusion Criteria

(Participants with Alcohol use Disorder):
Neurological, medical or other conditions that would interfere with MRI scanning (e.g., history of stroke, seizure, brain tumor, brain infection, traumatic brain injury, multiple sclerosis, dementia, non MRI-compliant metal device in body, pregnancy, claustrophobia, color blindness, severe hearing impairment, weight\>300 lbs., wheelchair-bound, tattoos as indicated by the guidelines established by the Zuckerman Institute MRI unit: https://mr.research.columbia.edu/
DSM 5 diagnoses of schizophrenia, schizoaffective disorder, or bipolar disorder
Any non-AUD psychiatric disorder that may, according to the investigator's judgment, require treatment over the course of the study
Significant suicide or violence risk
Currently taking psychotropic medication
Current substance use disorder other than AUD, tobacco use disorder or mild cannabis use disorder
Currently pregnant, attempting to become pregnant or nursing
Sufficiently socially unstable as to preclude participation (e.g. homeless).
Known history of allergy, intolerance, or hypersensitivity to disulfiram or its derivates
Contraindications to disulfiram treatment (e.g. liver disease, kidney disease, cardiac disease, seizure disorder, hypothyroidism, diabetes mellitus, pregnancy or lactation, allergy to disulfiram or thiuram derivatives)
Currently taking medications containing alcohol, metronidazole, isoniazid, paraldehyde, phenytoin, warfarin, or theophylline.
Treatment with concomitant medications that might interfere with disulfiram
A history of alcohol withdrawal seizures, delirium tremens or resistant alcohol withdrawal
Current moderate or severe alcohol withdrawal (CIWA \>9 with BAL\<0.05)
History of prior disulfiram treatment failure
Being abstinent for \> 7 days at the time of screening Exclusion Criteria (Healthy Volunteer Participants):
Neurological, medical or other conditions that would interfere with MRI scanning (e.g., history of stroke, seizure, brain tumor, brain infection, traumatic brain injury, multiple sclerosis, dementia, non MRI-compliant metal device in body, pregnancy, claustrophobia, color blindness, severe hearing impairment, weight\>300 lbs., wheelchair- bound, tattoos as indicated by the guidelines established by the ZI MRI unit: https://mr.research.columbia.edu/
DSM 5 diagnoses of schizophrenia, schizoaffective disorder, or bipolar disorder
Any psychiatric disorder that may, according to the investigator's judgment, require treatment over the course of the study
Significant suicide or violence risk
Currently taking psychotropic medication
Current substance use disorder other than tobacco use disorder or mild cannabis use disorder
Currently pregnant, attempting to become pregnant or nursing
Sufficiently socially unstable as to preclude participation (e.g., homeless).
A diagnosis of AUD of any severity

Not sure if you qualify? Submit your interest and a study coordinator will help determine your eligibility.

Frequently Asked Questions

Q:Is this study available in New York?

Yes, this clinical trial (NCT06793488) has an active research site in New York, NY that is currently enrolling participants.

Q:Is it safe to participate?

Clinical trials follow strict safety guidelines and ethical standards. This study has been reviewed and approved, and participants are closely monitored by medical professionals. You can withdraw at any time.

Q:Will I be compensated?

Many clinical trials offer compensation for your time and travel expenses. Specific compensation details will be discussed during the screening process. All study-related medical care is provided at no cost.

Q:Can I leave the trial if I change my mind?

Absolutely. Participation is completely voluntary. You have the right to withdraw from the study at any time, for any reason, without penalty.

Still have questions? Our study coordinators are here to help.

Alcohol Use Disorder Treatment Options in New York, NY

If you're searching for alcohol use disorder treatment options in New York, NY, this clinical trial (NCT06793488) may be an excellent opportunity. Clinical trials provide access to cutting-edge treatments that aren't yet available to the general public, often at no cost to participants.

Our New York research site is actively enrolling participants for this clinical trial. You'll receive care from experienced alcohol use disorder specialists who are at the forefront of medical research. All study-related care, including examinations, treatments, and monitoring, is provided at no cost to qualified participants.

Looking for more options? Browse all alcohol use disorder clinical trials near you to find additional studies recruiting in your area.

More Substance Use Disorder Trials in New York, NY

See all substance use disorder clinical trials recruiting in New York — not just this study.

Browse Substance Use Disorder Trials in New York →

Browse More Trials by Condition

Substance Use Disorder TrialsAll Conditions →

Ready to Join in New York?

Take the first step toward participating in this groundbreaking clinical trial

Secure · Expert Care · New York, NY